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Paid Clinical Trials in West Virginia

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  • Study Evaluating the Efficacy and Safety of SBI-087 in Seropositive Subjects With Active Rheumatoid Arthritis

    Condition:   Active Rheumatoid Arthritis
    Intervention:   Drug: SBI-087
    Sponsor:   Wyeth
    Recruiting - verified November 2009

  • Assessing the Safety/Efficacy of Asacol® Given Every 12 Hours to Children and Adolescents for the Maintenance of Remission of Ulcerative Colitis

    Condition:   Ulcerative Colitis
    Interventions:   Drug: Asacol (mesalamine), High Dose;   Drug: Asacol (mesalamine), Low Dose
    Sponsor:   Procter and Gamble
    Recruiting - verified October 2009

  • Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma

    Conditions:   Lymphoma;   Lymphoproliferative Disorder
    Interventions:   Other: biologic sample preservation procedure;   Other: informational intervention
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of Bone Marrow and Blood Samples From Patients With Leukemia or Other Hematopoietic Cancers

    Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
    Interventions:   Genetic: cytogenetic analysis;   Genetic: fluorescence in situ hybridization
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI);   Eastern Cooperative Oncology Group
    Recruiting - verified November 2009

  • Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Liver Cancer

    Condition:   Liver Cancer
    Interventions:   Drug: cisplatin;   Drug: doxorubicin hydrochloride;   Drug: fluorouracil;   Drug: irinotecan hydrochloride;   Drug: vincristine sulfate;   Procedure: liver transplantation;   Procedure: observation
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Adaptive Cardiac Resynchronization Therapy Study

    Condition:   Heart Failure
    Interventions:   Device: Cardiac Resynchronization Therapy-Defibrillator (CRT-D);   Other: Adaptive CRT (aCRT) Pacing
    Sponsor:   Medtronic Cardiac Rhythm Disease Management
    Recruiting - verified November 2009

  • A Study to Determine the Safety and Efficacy of Albiglutide Administered in Combination With Insulin Glargine

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Drug: insulin glargine + preprandial lispro insulin;   Biological: albiglutide + insulin glargine
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Study of Blood Samples From Newborns With Down Syndrome

    Condition:   Leukemia
    Interventions:   Genetic: DNA analysis;   Genetic: RNA analysis;   Genetic: cytogenetic analysis;   Genetic: fluorescence in situ hybridization;   Genetic: gene expression analysis;   Genetic: microarray analysis;   Genetic: mutation analysis;   Genetic: polymerase chain reaction;   Genetic: polymorphism analysis;   Other: flow cytometry;   Other: laboratory biomarker analysis;   Other: pharmacological study
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of Patients With Advanced Non-Small Cell Lung Cancer

    Condition:   Advanced Non-Small Cell Lung Cancer
    Interventions:   Drug: Pemetrexed;   Drug: Carboplatin;   Drug: Paclitaxel;   Biological: Bevacizumab
    Sponsor:   Eli Lilly and Company
    Recruiting - verified November 2009

  • An Extension To The B1451027 Protocol To Evaluate The Long Term Safety And Tolerability Of Dimebon In Patients With Alzheimer's Disease

    Condition:   Alzheimer's Disease
    Intervention:   Drug: Dimebon
    Sponsors:   Pfizer;   Medivation, Inc.
    Recruiting - verified November 2009

  • A Study to Evaluate the Safety and Efficacy of Denosumab and Ibandronate in Postmenopausal Women Sub-Optimally Treated With Daily or Weekly Bisphosphonates

    Condition:   Postmenopausal Osteoporosis
    Interventions:   Drug: Ibandronate;   Drug: Denosumab
    Sponsor:   Amgen
    Not yet recruiting - verified November 2009

  • Abatacept Versus Adalimumab Head-to-Head

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: Abatacept;   Drug: Adalimumab
    Sponsor:   Bristol-Myers Squibb
    Recruiting - verified November 2009

  • Collecting and Storing Blood and Bone Marrow Samples From Patients With Hematologic Cancer

    Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma

    Conditions:   Chordoma;   Desmoid Tumor;   Sarcoma
    Interventions:   Genetic: reverse transcriptase-polymerase chain reaction;   Other: biologic sample preservation procedure;   Other: laboratory biomarker analysis
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of VX-770 in Cystic Fibrosis Subjects Age 12 and Older With the G551D Mutation

    Condition:   Cystic Fibrosis
    Interventions:   Drug: VX-770;   Drug: Placebo
    Sponsors:   Vertex Pharmaceuticals Incorporated;   Cystic Fibrosis Foundation
    Recruiting - verified November 2009

  • Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma

    Condition:   Neuroblastoma
    Interventions:   Genetic: loss of heterozygosity analysis;   Other: cytology specimen collection procedure;   Procedure: biopsy
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

    Conditions:   Leukemia;   Lymphoma
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Biological Samples From Patients With Ewing Sarcoma

    Condition:   Sarcoma
    Interventions:   Other: biologic sample preservation procedure;   Other: medical chart review
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of Kidney Tumors in Young Patients

    Conditions:   Kidney Cancer;   Precancerous/Nonmalignant Condition
    Interventions:   Genetic: loss of heterozygosity analysis;   Genetic: polymerase chain reaction;   Genetic: polymorphism analysis;   Other: immunohistochemistry staining method;   Procedure: computed tomography;   Procedure: magnetic resonance imaging
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma

    Condition:   Sarcoma
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Biological Samples From Young Patients With Hodgkin's Lymphoma

    Condition:   Lymphoma
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer

    Conditions:   Leukemia;   Neoplasm of Uncertain Malignant Potential;   Unspecified Childhood Solid Tumor, Protocol Specific
    Intervention:   Other: cytology specimen collection procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • A Study Of Tocilizumab in Patients With Moderate to Severe Active Rheumatoid Arthritis Who Have an Inadequate Response to or Are Unable to Tolerate Biologic and Non-Biologic DMARDs

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: tocilizumab;   Drug: Nonbiologic DMARDs of investigator's choice
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009

  • A Clinical Trial Comparing the Combination of TC Plus Bevacizumab to TC Alone and to TAC for Women With Node-Positive or High-Risk Node-Negative, HER2-Negative Breast Cancer

    Condition:   Breast Cancer
    Interventions:   Drug: bevacizumab;   Drug: docetaxel;   Drug: doxorubicin;   Drug: cyclophosphamide;   Drug: cyclophosphamide;   Drug: pegfilgrastim
    Sponsors:   National Surgical Adjuvant Breast and Bowel Project (NSABP);   Genentech;   US Oncology Research
    Recruiting - verified October 2009

  • Cisplatin and Etoposide Phosphate With or Without GDC-0449 or Cixutumumab in Treating Patients With Extensive-Stage Small Cell Lung Cancer

    Condition:   Lung Cancer
    Interventions:   Biological: cixutumumab;   Drug: Hedgehog antagonist GDC-0449;   Drug: cisplatin;   Drug: etoposide phosphate
    Sponsors:   Eastern Cooperative Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study Evaluating the Effects of Neratinib in Women With Early Stage Breast Cancer

    Condition:   Breast Cancer
    Interventions:   Drug: neratinib;   Other: placebo
    Sponsor:   Wyeth
    Recruiting - verified November 2009

  • The Effect Of Acadesine On Reducing Cardiovascular and Cerebrovascular Adverse Events In Coronary Artery Bypass Graft (CABG) Surgery (Study P05633AM1)

    Conditions:   Coronary Artery Bypass;   Myocardial Infarction;   Ventricular Dysfunction, Left;   Stroke;   Cardiopulmonary Bypass
    Interventions:   Drug: Acadesine;   Drug: Normal Saline
    Sponsor:   Schering-Plough
    Recruiting - verified October 2009

  • Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement

    Conditions:   Breast Cancer;   Metastatic Cancer;   Multiple Myeloma and Plasma Cell Neoplasm;   Musculoskeletal Complications;   Pain;   Prostate Cancer;   Urinary Complications
    Intervention:   Drug: zoledronic acid
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of Immunotherapy to Treat Advanced Prostate Cancer

    Condition:   Prostate Cancer
    Interventions:   Drug: Ipilimumab;   Drug: Placebo
    Sponsor:   Bristol-Myers Squibb
    Recruiting - verified September 2009

  • Immunogenicity of GSKs' MMR Vaccine (209762) vs. M-M-R® II, When Given With Routine Vaccines at 12-15 Months of Age

    Condition:   Diseases Caused by Measles, Mumps, Rubella and Varicella Viruses
    Interventions:   Biological: Havrix®;   Biological: Prevnar®;   Biological: M-M-R® II (Merck and Co);   Biological: Varivax®;   Biological: GSK Biological's investigational vaccine 209762
    Sponsor:   GlaxoSmithKline
    Recruiting - verified October 2009

  • A Phase 3 Study Comparing 2 Doses of CP-690,550 vs. Placebo for the Treatment of Rheumatoid Arthritis in Patients on Other Background Arthritis Medications

    Condition:   Arthritis, Rheumatoid
    Interventions:   Drug: CP-690,550;   Drug: CP-690,550;   Drug: Placebo;   Drug: Placebo
    Sponsor:   Pfizer
    Recruiting - verified November 2009

  • Phase 3 Study Comparing 2 Doses of CP-690,550 and the Active Comparator, Humira (Adalimumab) vs. Placebo for Treatment of Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: CP 690,550;   Drug: CP-690,550;   Other: Placebo;   Other: Placebo;   Biological: Biologic TNFi
    Sponsor:   Pfizer
    Recruiting - verified November 2009

  • 2-Year Phase 3 Study Of CP-690,550 In Patients With Active Rheumatoid Arthritis On Background Methotrexate

    Condition:   Arthritis, Rheumatoid
    Interventions:   Drug: CP-690,550;   Drug: CP-690,550;   Drug: CP-690,550;   Drug: CP-690,550;   Drug: Placebo;   Drug: CP-690,550;   Drug: Placebo;   Drug: CP-690,550
    Sponsor:   Pfizer
    Recruiting - verified November 2009

  • Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

    Conditions:   Anemia;   Leukemia;   Myelodysplastic Syndromes
    Interventions:   Biological: epoetin alfa;   Drug: lenalidomide
    Sponsors:   Eastern Cooperative Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes.

    Condition:   Type 2 Diabetes Mellitus
    Interventions:   Drug: metformin + glimepiride + pioglitazone placebo + albiglutide placebo;   Drug: metformin + glimepiride + pioglitazone + albiglutide placebo;   Biological: metformin + glimepiride + pioglitazone placebo + albiglutide
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes

    Condition:   Type 2 Diabetes Mellitus
    Interventions:   Drug: glimepiride;   Drug: metformin;   Drug: sitagliptin;   Biological: albiglutide
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • A Phase 3 Study To Evaluate The Safety And Tolerability Of Dimebon Patients With Mild To Moderate Alzheimer's Disease

    Condition:   Alzheimer's Disease
    Interventions:   Drug: Dimebon;   Drug: Placebo;   Drug: Dimebon;   Drug: Placebo
    Sponsors:   Pfizer;   Medivation, Inc.
    Recruiting - verified November 2009

  • PF-00299804 As a Single Oral Agent In Untreated Adenocarcinoma Of The Lung In Non-Smokers Or Former Light Smokers

    Condition:   Carcinoma, Non-small Cell
    Intervention:   Drug: PF-00299804
    Sponsor:   Pfizer
    Recruiting - verified November 2009

  • A Dose-ranging Safety and Efficacy Study of Ecallantide to Reduce Surgical Blood Loss Volume

    Conditions:   Bloodloss;   Surgical Procedures, Operative
    Interventions:   Drug: ecallantide;   Drug: placebo
    Sponsor:   Cubist Pharmaceuticals
    Recruiting - verified November 2009

  • A Phase 3 Study Comparing 2 Doses of CP-690,550 vs. Placebo for Treatment of Rheumatoid Arthritis

    Condition:   Arthritis, Rheumatoid
    Interventions:   Drug: CP-690,550;   Drug: CP-690,550;   Drug: Placebo;   Drug: Placebo
    Sponsor:   Pfizer
    Recruiting - verified November 2009

  • Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer

    Conditions:   Endometrial Cancer;   Fatigue;   Neurotoxicity
    Interventions:   Drug: carboplatin;   Drug: paclitaxel;   Radiation: brachytherapy;   Radiation: intensity-modulated radiation therapy;   Radiation: radiation therapy
    Sponsors:   Gynecologic Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of NNZ-2566 in Patients With Traumatic Brain Injury

    Condition:   Brain Injuries
    Intervention:   Drug: NNZ-2566
    Sponsor:   Neuren Pharmaceuticals Limited
    Not yet recruiting - verified November 2009

  • Post-marketing, Observational Study of HUMIRA® (Adalimumab) in Patients With Chronic Plaque Psoriasis (Ps)

    Condition:   Chronic Plaque Psoriasis
    Intervention:   Biological: HUMIRA® (adalimumab)
    Sponsor:   Abbott
    Recruiting - verified October 2009

  • A Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their Tumor.

    Condition:   Resected Stage III Melanoma With Macroscopic Involvement
    Interventions:   Drug: GSK 2132231A;   Drug: Placebo
    Sponsor:   GlaxoSmithKline
    Recruiting - verified July 2009

  • Bevacizumab and Paclitaxel, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, or Ixabepilone in Treating Patients With Locally Recurrent, Stage IIIB, or Stage IV Breast Cancer

    Conditions:   Breast Cancer;   Chemotherapeutic Agent Toxicity;   Long-term Effects Secondary to Cancer Therapy in Adults;   Neurotoxicity;   Psychosocial Effects of Cancer and Its Treatment
    Interventions:   Biological: bevacizumab;   Drug: ixabepilone;   Drug: paclitaxel;   Drug: paclitaxel albumin-stabilized nanoparticle formulation
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Global Study to Assess the Safety and Effectiveness of DU-176b vs Standard Practice of Dosing With Warfarin in Patients With Atrial Fibrillation

    Conditions:   Stroke;   Atrial Fibrillation;   Embolism
    Interventions:   Drug: warfarin tablets;   Drug: DU-176b tablets (high dose regimen);   Drug: DU-176b tablets (low dose regimen)
    Sponsors:   Daiichi Sankyo Inc.;   The TIMI Study Group
    Recruiting - verified November 2009

  • Neuropsychological and Behavioral Testing in Young Patients With Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET)

    Conditions:   Brain and Central Nervous System Tumors;   Chemotherapeutic Agent Toxicity;   Cognitive/Functional Effects;   Neurotoxicity;   Psychosocial Effects of Cancer and Its Treatment;   Radiation Toxicity;   Therapy-related Toxicity
    Interventions:   Other: questionnaire administration;   Procedure: cognitive assessment;   Procedure: psychosocial assessment and care;   Procedure: quality-of-life assessment
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Phase 2 Study of Efficacy and Safety of Apricoxib/Placebo With Either Docetaxel or Pemetrexed in Non-Small Cell Lung Cancer Patients

    Conditions:   Lung Cancer;   Non Small Cell Lung Cancer
    Interventions:   Drug: apricoxib;   Drug: Placebo
    Sponsors:   University of Maryland;   Tragara Pharmaceuticals, Inc.
    Recruiting - verified November 2009

  • Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy

    Condition:   Breast Cancer
    Interventions:   Biological: trastuzumab;   Radiation: radiation therapy
    Sponsors:   National Surgical Adjuvant Breast and Bowel Project (NSABP);   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • A Randomized Trial Of PF-00299804 Taken Orally Versus Erlotinib Taken Orally For Treatment Of Advanced Non-Small Cell Lung Cancer That Has Progressed After One Or Two Prior Chemotherapy Regimen.

    Condition:   Non-small Cell Lung Cancer
    Interventions:   Drug: Erlotinib;   Drug: PF-00299804
    Sponsor:   Pfizer
    Recruiting - verified November 2009

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