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Paid Clinical Trials in Vermont

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  • Clinical Evaluation of a Multifocal Contact Lens on Symptomatic Patients

    Condition:   Presbyopia
    Interventions:   Device: Etafilcon A Multifocal Contact Lens;   Device: Etafilcon A Contact Lens
    Sponsors:   Vistakon;   Visioncare Research Ltd.
    Recruiting - verified November 2009

  • Study to Investigate the Efficacy and Tolerability of AZD1446 in Adult ADHD Patients.

    Condition:   Adult ADHD
    Interventions:   Drug: AZD1446;   Drug: AZD1446;   Drug: AZD1446;   Drug: Placebo
    Sponsor:   AstraZeneca
    Recruiting - verified November 2009

  • Treatment of Claudication With a Peristaltic Pulse Pneumatic Device

    Condition:   Intermittent Claudication
    Interventions:   Device: Peristaltic pulse PCD;   Other: Exercise and lifestyle counseling
    Sponsors:   White River Junction VAMC;   NormaTec Industries LP
    Not yet recruiting - verified November 2009

  • Outcomes of Oncology Therapy in the Elderly: Trajectory of Functional Decline and Correlates of Change

    Condition:   Cancer
    Intervention:  
    Sponsor:   University of Vermont
    Recruiting - verified November 2009

  • Study of Bone Marrow and Blood Samples in Patients With Untreated Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia Enrolled on Clinical Trial CALGB-9621 or CALGB-9720

    Condition:   Leukemia
    Intervention:   Other: laboratory biomarker analysis
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of Biomarkers in Blood and Bone Marrow Samples From Patients With Previously Untreated Chronic Lymphocytic Leukemia

    Condition:   Leukemia
    Interventions:   Genetic: fluorescence in situ hybridization;   Genetic: mutation analysis;   Genetic: nucleic acid sequencing;   Genetic: polymerase chain reaction;   Genetic: western blotting;   Other: flow cytometry;   Other: laboratory biomarker analysis
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of Blood and Bone Marrow Samples in Patients With Chronic Myelogenous Leukemia Enrolled on a CALGB Clinical Trial

    Condition:   Leukemia
    Interventions:   Genetic: DNA analysis;   Genetic: Southern blotting;   Genetic: cytogenetic analysis;   Genetic: polymerase chain reaction
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Methylnaltrexone for Opioid-induced Constipation in Cancer Patients

    Conditions:   Neoplasms;   Constipation;   Opioid-Related Disorders
    Intervention:   Drug: Methylnaltrexone bromide
    Sponsor:   University of Vermont
    Recruiting - verified October 2009

  • ActiveStep Comparative Effectiveness Trial

    Condition:   Balance
    Interventions:   Device: ActiveStep Treadmill;   Other: Physical Therapy
    Sponsor:   Dartmouth-Hitchcock Medical Center
    Not yet recruiting - verified November 2009

  • Natural History of Attempts to Stop Smoking

    Condition:   Tobacco Use Cessation
    Intervention:  
    Sponsors:   University of Vermont;   National Institute on Drug Abuse (NIDA)
    Recruiting - verified November 2009

  • A Phase 3b Study of Vernakalant Injection in Patients With Recent Onset Symptomatic Atrial Fibrillation (AF)

    Condition:   Atrial Fibrillation
    Interventions:   Drug: Vernakalant;   Drug: Placebo
    Sponsors:   Astellas Pharma Inc;   Cardiome Pharma
    Recruiting - verified November 2009

  • A Study in Relapse Prevention of Treatment-resistant Depression

    Condition:   Treatment Resistant Depression
    Interventions:   Drug: Olanzapine and Fluoxetine combination;   Drug: Fluoxetine
    Sponsor:   Eli Lilly and Company
    Recruiting - verified November 2009

  • A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis

    Condition:   Sarcoidosis
    Interventions:   Drug: golimumab;   Drug: ustekinumab;   Drug: Placebo
    Sponsor:   Centocor, Inc.
    Recruiting - verified November 2009

  • Study of VX-770 in Cystic Fibrosis Subjects Age 12 and Older Homozygous for the F508del-CFTR Mutation

    Condition:   Cystic Fibrosis
    Interventions:   Drug: VX-770;   Drug: Placebo
    Sponsors:   Vertex Pharmaceuticals Incorporated;   Cystic Fibrosis Foundation
    Recruiting - verified November 2009

  • COntrolled MyeloFibrosis Study With ORal JAK Inhibitor Treatment: The COMFORT-I Trial

    Condition:   Myelofibrosis
    Interventions:   Drug: INCB018424;   Drug: Placebo
    Sponsor:   Incyte Corporation
    Recruiting - verified November 2009

  • Safety of QMF149 Twisthaler® in Adolescent and Adult Patients With Asthma

    Condition:   Asthma
    Interventions:   Drug: QMF149 Twisthaler®;   Drug: Mometasone Twisthaler®
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified November 2009

  • Adult Study / OROS Methylphenidate Hydrochloride (HCL) (OROS MPH) in Adults With Attention Deficit Hyperactivity Disorder (ADHD)

    Condition:   Attention Deficit Disorder With Hyperactivity
    Interventions:   Drug: OROS MPH;   Drug: Placebo
    Sponsor:   Ortho-McNeil Janssen Scientific Affairs, LLC
    Recruiting - verified November 2009

  • A Study of Pediatric Patients With Attention Deficit/Hyperactivity Disorder

    Condition:   Attention Deficit Hyperactivity Disorder
    Interventions:   Drug: LY2216684;   Drug: Methylphenidate;   Drug: Placebo (tablet);   Drug: Placebo (capsule)
    Sponsor:   Eli Lilly and Company
    Recruiting - verified November 2009

  • Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors

    Condition:   Brain and Central Nervous System Tumors
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma

    Conditions:   Chordoma;   Desmoid Tumor;   Sarcoma
    Interventions:   Genetic: reverse transcriptase-polymerase chain reaction;   Other: biologic sample preservation procedure;   Other: laboratory biomarker analysis
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study Evaluating the Safety and Efficacy of Bapineuzumab in Subjects With Alzheimer Disease

    Condition:   Alzheimer Disease
    Interventions:   Drug: bapineuzumab;   Drug: placebo
    Sponsor:   Wyeth
    Recruiting - verified November 2009

  • Effect of LY2062430 on the Progression of Alzheimer's Disease

    Condition:   Alzheimer's Disease
    Interventions:   Drug: LY2062430;   Drug: Placebo
    Sponsor:   Eli Lilly and Company
    Recruiting - verified November 2009

  • Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma

    Condition:   Neuroblastoma
    Interventions:   Genetic: loss of heterozygosity analysis;   Other: cytology specimen collection procedure;   Procedure: biopsy
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Blood, Bone Marrow, and Other Samples From Patients With Acute Leukemia, Chronic Leukemia, or Myelodysplastic Syndromes

    Conditions:   Leukemia;   Lymphoma;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Biological Samples From Patients With Ewing Sarcoma

    Condition:   Sarcoma
    Interventions:   Other: biologic sample preservation procedure;   Other: medical chart review
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting Tumor Samples From Patients With Gynecological Tumors

    Condition:   Cancer
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Gynecologic Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer

    Conditions:   Leukemia;   Neoplasm of Uncertain Malignant Potential;   Unspecified Childhood Solid Tumor, Protocol Specific
    Intervention:   Other: cytology specimen collection procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma

    Condition:   Sarcoma
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

    Conditions:   Leukemia;   Lymphoma
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Biological Samples From Young Patients With Hodgkin's Lymphoma

    Condition:   Lymphoma
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of Kidney Tumors in Young Patients

    Conditions:   Kidney Cancer;   Precancerous/Nonmalignant Condition
    Interventions:   Genetic: loss of heterozygosity analysis;   Genetic: polymerase chain reaction;   Genetic: polymorphism analysis;   Other: immunohistochemistry staining method;   Procedure: computed tomography;   Procedure: magnetic resonance imaging
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • A Boston Scientific Trial of the EPIC™ Nitinol Stent System in the Treatment of Atherosclerotic Lesions in Iliac Arteries

    Condition:   Iliac Stenoses
    Intervention:   Device: Epic™ Nitinol Stent System
    Sponsor:   Boston Scientific Corporation
    Recruiting - verified October 2009

  • Study Comparing 3 Dosage Levels of SAM-531 in Outpatients With Mild to Moderate Alzheimer Disease.

    Condition:   Alzheimer Disease
    Intervention:   Drug: Placebo
    Sponsor:   Wyeth
    Recruiting - verified November 2009

  • A Study Of Tocilizumab in Patients With Moderate to Severe Active Rheumatoid Arthritis Who Have an Inadequate Response to or Are Unable to Tolerate Biologic and Non-Biologic DMARDs

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: tocilizumab;   Drug: Nonbiologic DMARDs of investigator's choice
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009

  • Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

    Condition:   Brain and Central Nervous System Tumors
    Interventions:   Biological: bevacizumab;   Drug: temozolomide;   Other: placebo
    Sponsors:   Radiation Therapy Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • A Study to Evaluate 3 Different Doses of JNJ-31001074 in the Treatment of Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)

    Conditions:   Attention Deficit Hyperactivity Disorder;   Attention Deficit Disorders With Hyperactivity
    Interventions:   Drug: JNJ-31001074 1 mg/d;   Drug: JNJ-31001074 10 mg/d;   Drug: Atomoxetine 80 mg/d;   Drug: OROS methylphenidate HCl 54 mg/d;   Drug: JNJ-31001074 3 mg/d;   Drug: Placebo
    Sponsor:   Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
    Recruiting - verified November 2009

  • Study Evaluating the Effects of Neratinib in Women With Early Stage Breast Cancer

    Condition:   Breast Cancer
    Interventions:   Drug: neratinib;   Other: placebo
    Sponsor:   Wyeth
    Recruiting - verified November 2009

  • Prochymal® (Human Adult Stem Cells) Intravenous Infusion Following Acute Myocardial Infarction (AMI)

    Condition:   Myocardial Infarction
    Interventions:   Drug: Prochymal®;   Drug: Placebo
    Sponsor:   Osiris Therapeutics
    Recruiting - verified November 2009

  • Trial of TPI 287 as a Single Agent and in Combination With Temozolomide in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastoma

    Conditions:   Relapsed Neuroblastoma;   Refractory Neuroblastoma;   Relapsed Medulloblastoma;   Refractory Medulloblastoma
    Intervention:   Drug: TPI 287
    Sponsors:   University of Vermont;   Archer Biosciences, Inc.
    Recruiting - verified October 2009

  • Safety and Efficacy of Caripazine As Adjunctive Therapy In Major Depressive Disorder

    Condition:   Major Depressive Disorder
    Interventions:   Drug: Antidepressant + placebo;   Drug: Antidepressant + cariprazine (0.1-0.3 mg/day);   Drug: Antidepressant + cariprazine (1-2 mg/d)
    Sponsors:   Forest Laboratories;   Gedeon Richter Ltd.
    Recruiting - verified November 2009

  • Safety and Efficacy of RGH-188 (Cariprazine) in Bipolar Depression

    Condition:   Bipolar Depression
    Interventions:   Drug: cariprazine;   Drug: cariprazine;   Drug: placebo
    Sponsors:   Forest Laboratories;   Gedeon Richter Ltd.
    Recruiting - verified October 2009

  • Treatment for Aggression and Agitation in Patients With Alzheimer's Disease

    Condition:   Alzheimer's Disease
    Interventions:   Drug: LY451395;   Drug: Placebo
    Sponsor:   Eli Lilly and Company
    Recruiting - verified November 2009

  • Preliminary Efficacy and Safety Study of ST101 Plus Aricept in Alzheimer's Disease

    Condition:   Alzheimer's Disease
    Interventions:   Drug: ST101;   Drug: ST101;   Drug: ST101;   Drug: Placebo
    Sponsor:   Sonexa Therapeutics, Inc.
    Recruiting - verified November 2009

  • Preliminary Efficacy and Safety Study of ST101 in Alzheimer's Disease

    Condition:   Alzheimer's Disease
    Interventions:   Drug: ST101;   Drug: ST101;   Drug: ST101;   Drug: Placebo
    Sponsor:   Sonexa Therapeutics, Inc.
    Recruiting - verified November 2009

  • A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes.

    Condition:   Type 2 Diabetes Mellitus
    Interventions:   Drug: metformin + glimepiride + pioglitazone placebo + albiglutide placebo;   Drug: metformin + glimepiride + pioglitazone + albiglutide placebo;   Biological: metformin + glimepiride + pioglitazone placebo + albiglutide
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes

    Condition:   Type 2 Diabetes Mellitus
    Interventions:   Drug: glimepiride;   Drug: metformin;   Drug: sitagliptin;   Biological: albiglutide
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Phase 2b Study of Cetuximab With Platinum-Based Chemo as First Line Treatment of Recurrent or Advanced NSCLC

    Condition:   Non-small Cell Lung Cancer
    Interventions:   Drug: Cetuximab;   Drug: Paclitaxel;   Drug: Carboplatin;   Drug: Gemcitabine;   Drug: Cisplatin
    Sponsors:   Accelerated Community Oncology Research Network;   ImClone LLC;   Advanced Clinical Trial Solutions, LLC
    Recruiting - verified November 2009

  • An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome.

    Conditions:   Acute Coronary Syndrome;   Myocardial Infarction;   Myocardial Ischemia;   Unstable Angina
    Intervention:   Drug: Rivaroxaban; Placebo
    Sponsors:   Johnson & Johnson Pharmaceutical Research & Development, L.L.C.;   Bayer
    Recruiting - verified November 2009

  • Study Evaluating The Effects Of Bazedoxifene/Conjugated Estrogens On Endometrial Safety And Postmenopausal Osteoporosis

    Conditions:   Menopause;   Osteoporosis
    Interventions:   Drug: bazedoxifene 20 mg/ conjugated estrogens 0.45 mg;   Drug: bazedoxifene 20 mg/ conjugated estrogens 0.625 mg;   Drug: bazedoxifene 20 mg;   Drug: conjugated estrogens 0.45 mg/ medroxyprogesterone acetate 1.5 mg;   Drug: Placebo
    Sponsor:   Wyeth
    Recruiting - verified November 2009

  • Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer

    Conditions:   Endometrial Cancer;   Fatigue;   Neurotoxicity
    Interventions:   Drug: carboplatin;   Drug: paclitaxel;   Radiation: brachytherapy;   Radiation: intensity-modulated radiation therapy;   Radiation: radiation therapy
    Sponsors:   Gynecologic Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

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