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Paid Clinical Trials in Tennessee

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  • A Study to Evaluate the Safety and Efficacy of Tazarotene Foam, 0.1%, in Subjects With Common Facial Acne

    Condition:   Acne Vulgaris
    Interventions:   Drug: Tazarotene foam;   Drug: Vehicle Foam
    Sponsor:   Stiefel, a GSK Company
    Recruiting - verified November 2009

  • Safety and Efficacy of a Glaucoma Drug Delivery System

    Conditions:   Open-Angle Glaucoma;   Ocular Hypertension
    Interventions:   Drug: bimatoprost;   Drug: bimatoprost;   Drug: Placebo
    Sponsor:   Vistakon Pharmaceuticals
    Recruiting - verified November 2009

  • A Study With RO4917523 in Patients With Fragile X Syndrome

    Condition:   Fragile X Syndrome
    Interventions:   Drug: RO4917523;   Drug: Placebo;   Drug: RO4917523;   Drug: Placebo
    Sponsor:   Hoffmann-La Roche
    Not yet recruiting - verified November 2009

  • Combination of Cisplatin, Cetuximab and Temsirolimus in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

    Condition:   Squamous Cell Carcinoma of the Head and Neck
    Interventions:   Drug: temsirolimus;   Drug: cisplatin;   Drug: cetuximab
    Sponsors:   University of Tennessee Cancer Institute;   National Comprehensive Cancer Network (NCCN)
    Not yet recruiting - verified November 2009

  • Clinical Evaluation of a Silicone Hydrogel Lens

    Condition:   Lotrafilcon A Contact Lens Use
    Intervention:  
    Sponsor:   Novartis
    Recruiting - verified November 2009

  • Multi-Site Evaluation of Progressive Tinnitus Management

    Condition:   Tinnitus
    Interventions:   Procedure: Progressive Tinnitus Management;   Procedure: Usual Care
    Sponsor:   Department of Veterans Affairs
    Not yet recruiting - verified November 2009

  • Risk of Psychopathology and Neurocognitive Impairment in Leukemia Survivors

    Conditions:   Neurocognitive Impairment;   Acute Lymphoblastic Leukemia
    Intervention:   Other: Neurocognitive and behavioral evaluation
    Sponsors:   St. Jude Children's Research Hospital;   National Cancer Institute (NCI);   National Institute of Mental Health (NIMH)
    Not yet recruiting - verified November 2009

  • A Dose-escalation Trial of SGN-75 in CD70-positive Non-Hodgkin Lymphoma or Renal Cell Carcinoma

    Conditions:   Carcinoma, Renal Cell;   Lymphoma, Non-Hodgkin
    Intervention:   Drug: SGN-75
    Sponsor:   Seattle Genetics, Inc.
    Recruiting - verified November 2009

  • Developmental and Augmented Intervention for Facilitating Expressive Language

    Conditions:   Joint Engagement;   Enhanced Milieu Training;   Augmentative Communication (AAC)
    Intervention:   Behavioral: JAE Intervention
    Sponsors:   Autism Speaks;   Hugo W. Moser Research Institute at Kennedy Krieger, Inc.;   Vanderbilt University;   University of California, Los Angeles
    Recruiting - verified November 2009

  • A Phase IIb 78-week Study in Patients on a Basal Insulin +/- Metformin and/or Sulfonylurea and Are Not at Goal to Add BI 10773 vs. Placebo

    Condition:   Diabetes Mellitus, Type 2
    Intervention:   Drug: BI 10773
    Sponsor:   Boehringer Ingelheim Pharmaceuticals
    Recruiting - verified November 2009

  • BIBF 1120 or Placebo in Combination With Paclitaxel and Carboplatin in First Line Treatment of Ovarian Cancer

    Conditions:   Ovarian Neoplasms;   Peritoneal Neoplasms
    Interventions:   Drug: BIBF 1120;   Drug: Placebo
    Sponsor:   Boehringer Ingelheim Pharmaceuticals
    Not yet recruiting - verified November 2009

  • Vibration Intervention For Bone Enhancement In Childhood Cancer Survivors

    Conditions:   Bone Mineral Density;   Bone Strength
    Interventions:   Device: LMHF mechanical stimulation active device;   Device: LMHF mechanical stimulation placebo device
    Sponsors:   St. Jude Children's Research Hospital;   National Institutes of Health (NIH)
    Not yet recruiting - verified November 2009

  • Asparaginase-Erwinia in Treating Patients With Acute Lymphoblastic Leukemia, T- Cell Lymphoma, or B-Cell Lymphoma Who Are Allergic to Asparaginase or Pegaspargase

    Conditions:   Leukemia;   Lymphoma;   Lymphoproliferative Disorder
    Intervention:   Drug: asparaginase-Erwinia
    Sponsors:   Vanderbilt-Ingram Cancer Center;   National Cancer Institute (NCI)
    Recruiting - verified January 2009

  • Study Evaluating the Efficacy and Safety of SBI-087 in Seropositive Subjects With Active Rheumatoid Arthritis

    Condition:   Active Rheumatoid Arthritis
    Intervention:   Drug: SBI-087
    Sponsor:   Wyeth
    Recruiting - verified November 2009

  • A Study to Evaluate the Efficacy and Safety of Fluticasone Furoate (FF)/GW642444 Inhalation Powder in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

    Condition:   Pulmonary Disease, Chronic Obstructive
    Interventions:   Drug: GW642444 Inhalation Powder;   Drug: FF/GW642444 Inhalation Powder
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Identification of the Pericardiophrenic Vein During Cardiac Device Implant Procedures to Prevent Extracardiac Stimulation

    Condition:   Heart Failure
    Intervention:  
    Sponsor:   Cardiac Concepts, Inc.
    Recruiting - verified November 2009

  • The Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosis

    Condition:   Onychomycosis
    Interventions:   Drug: IDP-108;   Drug: Vehicle
    Sponsor:   Dow Pharmaceutical Sciences
    Not yet recruiting - verified November 2009

  • Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosis

    Condition:   Onychomycosis
    Interventions:   Drug: IDP-108;   Drug: Vehicle
    Sponsor:   Dow Pharmaceutical Sciences
    Not yet recruiting - verified November 2009

  • Study of A3309 in Patients With Chronic Idiopathic Constipation

    Conditions:   Constipation;   Chronic Constipation
    Intervention:   Drug: A3309
    Sponsor:   Albireo
    Recruiting - verified November 2009

  • Daily Everolimus in Combination With Trastuzumab and Vinorelbine in HER2/Neu Positive Women With Locally Advanced or Metastatic Breast Cancer

    Conditions:   HER2/Neu Over-expressing Locally Advanced Breast Cancer;   Metastatic Breast Cancer
    Interventions:   Drug: everolimus, vinorelbine, trastuzumab;   Drug: vinorelbine + trastuzumab
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified November 2009

  • Subjective Evaluation of Air Optix Aqua Amongst a Subset of the Contact Lens Wearing Population

    Condition:   Myopia
    Interventions:   Device: Air Optix Aqua (lotrafilcon B);   Device: habitual contact lenses
    Sponsor:   Novartis
    Recruiting - verified November 2009

  • Comparison Study of Two Different Surgical Clips During Laparoscopic Urologic Surgery

    Conditions:   Prostatectomy;   Nephrectomy;   Laparoscopy;   Robotics
    Interventions:   Device: Teleflex HemoLock clip;   Device: Aesculap U-clip
    Sponsor:   Vanderbilt University
    Recruiting - verified November 2009

  • Golimumab in Rheumatoid Arthritis Patients With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)

    Conditions:   Arthritis;   Arthritis, Rheumatoid;   Autoimmune Diseases
    Interventions:   Drug: golimumab;   Drug: golimumab or placebo;   Drug: golimumab or placebo
    Sponsors:   Centocor, Inc.;   Schering-Plough
    Recruiting - verified November 2009

  • Evaluation of Cardiovascular Health Outcomes Among Survivors

    Conditions:   Cardiovascular Risk;   Cancer
    Interventions:   Behavioral: lifestyle modification and telephone counseling;   Behavioral: lifestyle modification and telephone counseling
    Sponsors:   St. Jude Children's Research Hospital;   National Institutes of Health (NIH)
    Not yet recruiting - verified October 2009

  • Assessing the Safety/Efficacy of Asacol® Given Every 12 Hours to Children and Adolescents for the Maintenance of Remission of Ulcerative Colitis

    Condition:   Ulcerative Colitis
    Interventions:   Drug: Asacol (mesalamine), High Dose;   Drug: Asacol (mesalamine), Low Dose
    Sponsor:   Procter and Gamble
    Recruiting - verified October 2009

  • Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma

    Conditions:   Lymphoma;   Lymphoproliferative Disorder
    Interventions:   Other: biologic sample preservation procedure;   Other: informational intervention
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • The Effects of Ankle Foot Orthoses on Gait Efficiency in Children With Acute Lymphoblastic Leukemia and Foot Drop

    Conditions:   Foot Drop;   Acute Lymphoblastic Leukemia
    Interventions:   Device: AFO Device;   Device: AFO Device
    Sponsor:   St. Jude Children's Research Hospital
    Recruiting - verified October 2009

  • Collecting and Storing Blood Samples From Patients With Previously Untreated Non-Hodgkin Lymphoma

    Condition:   Lymphoma
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Consistency & Immunogenicity Study of 3 Lots of GSK's Hib Conjugate Vaccine Versus ActHIB & Pentacel in Healthy Infants

    Conditions:   Haemophilus Influenzae Type B Related Disease;   Pneumonia;   Meningitis;   Cellulitis;   Osteomyelitis;   Epiglottis
    Interventions:   Biological: GSK Biologicals' Haemophilus inluenzae type b vaccine (GSK 208108);   Biological: ActHIBTM;   Biological: PentacelTM;   Biological: PediarixTM;   Biological: PrevnarTM;   Biological: RotarixTM;   Biological: EngerixTM-B;   Biological: InfanrixTM
    Sponsor:   GlaxoSmithKline
    Not yet recruiting - verified November 2009

  • A Pharmacokinetic Study of RO5185426 in Combination With a Drug Cocktail in Patients With Metastatic Melanoma

    Condition:   Malignant Melanoma
    Interventions:   Drug: RO5185426;   Drug: Drug cocktail
    Sponsor:   Hoffmann-La Roche
    Not yet recruiting - verified October 2009

  • Intravenous (IV) Saline and Exercise in Postural Tachycardia Syndrome (POTS)

    Condition:   Postural Tachycardia Syndrome
    Interventions:   Drug: Saline;   Other: Placebo
    Sponsor:   Vanderbilt University
    Recruiting - verified October 2009

  • Efficacy and Safety of FS VH S/D 4 S-apr for Flap Adherence in Rhytidectomy

    Conditions:   Face-lift;   Facial Rhytidectomy
    Intervention:   Procedure: FS VH S/D 4 s-apr
    Sponsor:   Baxter Healthcare Corporation
    Recruiting - verified October 2009

  • Shanghai Parkinson's Study

    Condition:   Parkinson's Disease
    Intervention:  
    Sponsor:   National Institute of Environmental Health Sciences (NIEHS)
    Recruiting - verified September 2009

  • Immunogenicity and Safety of Inactivated H1N1 Swine-origin Influenza Monovalent Vaccine in Immunocompromised Children and Young Adults

    Condition:   H1N1 Pandemic Flu
    Intervention:  
    Sponsor:   St. Jude Children's Research Hospital
    Recruiting - verified October 2009

  • A Study to Evaluate the Efficacy and Safety of DR-103 for the Prevention of Pregnancy

    Condition:   Pregnancy Prevention
    Intervention:   Drug: DR-103
    Sponsor:   Teva Women's Health
    Recruiting - verified October 2009

  • The Efficacy and Safety of Adding Methotrexate to Etanercept in Psoriasis

    Condition:   Psoriasis
    Interventions:   Drug: Methotrexate and Etanercept;   Drug: Etanercept ONLY
    Sponsors:   Amgen;   Immunex Corporation
    Not yet recruiting - verified November 2009

  • Study of Bone Marrow and Blood Samples From Patients With Leukemia or Other Hematopoietic Cancers

    Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
    Interventions:   Genetic: cytogenetic analysis;   Genetic: fluorescence in situ hybridization
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI);   Eastern Cooperative Oncology Group
    Recruiting - verified November 2009

  • TAXUS Libertē Post Approval Study

    Condition:   Coronary Artery Disease
    Interventions:   Device: TAXUS Liberté Paclitaxel-Eluting Coronary Stent;   Drug: prasugrel;   Drug: placebo;   Drug: aspirin
    Sponsors:   Boston Scientific Corporation;   Eli Lilly and Company;   Daiichi Sankyo Inc.
    Not yet recruiting - verified November 2009

  • SB-681323 IV for Subjects at Risk of Acute Lung Injury or ARDS

    Conditions:   Acute Lung Injury (ALI);   Acute Respiratory Distress Syndrome (ARDS)
    Interventions:   Drug: SB-681323 Intravenous 7.5mg;   Drug: SB-681323 Intravenous 3mg;   Drug: SB-681323 Intravenous 7.5 mg;   Drug: SB-681323 Intravenous 10mg;   Other: Placebo
    Sponsor:   GlaxoSmithKline
    Not yet recruiting - verified November 2009

  • Treatment of Traumatic Brain Injury (TBI)-Related Attention Deficits

    Conditions:   Traumatic Brain Injury;   Attention Deficit Disorder
    Interventions:   Drug: Vyvanse;   Procedure: fMRI
    Sponsors:   Vanderbilt University;   Shire Pharmaceutical Development
    Recruiting - verified October 2009

  • Efficacy and Safety Study of JTT-654 in Type 2 Diabetic Patients

    Condition:   Type II Diabetes Mellitus
    Interventions:   Drug: JTT-654;   Drug: JTT-654 Placebo
    Sponsor:   Akros Pharma Inc.
    Recruiting - verified November 2009

  • Safety and Tolerability of TAK-491 Plus Chlorthalidone Compared to Olmesartan Medoxomil-Hydrochlorothiazide in Subjects With Essential Hypertension

    Condition:   Essential Hypertension
    Interventions:   Drug: TAK-491 and chlorthalidone;   Drug: Olmesartan medoxomil-hydrochlorothiazide
    Sponsor:   Takeda Global Research & Development Center, Inc.
    Recruiting - verified November 2009

  • A Study in Cancer Patients to Evaluate the Bioequivalence of Alternative Formulations of Lapatinib

    Conditions:   ErbB2 Overexpressing;   Metastatic Breast Cancer;   Solid Tumors
    Intervention:   Drug: lapatinib
    Sponsor:   GlaxoSmithKline
    Recruiting - verified October 2009

  • Safety of and Immune Response to an H1N1 Influenza Virus Vaccine in HIV Infected Children and Youth

    Conditions:   HIV Infections;   H1N1 Influenza Virus
    Intervention:   Biological: Influenza A (H1N1) 2009 monovalent vaccine
    Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
    Not yet recruiting - verified October 2009

  • Novartis H1N1 Vaccine in Pregnant Women

    Condition:   Influenza
    Intervention:   Biological: Inactivated H1N1 Vaccine
    Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
    Recruiting - verified November 2009

  • A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42160443 in Patients With Diabetic Painful Neuropathy

    Conditions:   Pain;   Diabetic Neuropathy, Painful
    Interventions:   Drug: JNJ-42160443;   Drug: Placebo
    Sponsor:   Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
    Recruiting - verified November 2009

  • Safety of and Immune Response to an H1N1 Influenza Vaccine in HIV Infected Pregnant Women

    Conditions:   HIV Infections;   H1N1 Influenza Virus
    Intervention:   Biological: Influenza A (H1N1) monovalent vaccine
    Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
    Recruiting - verified October 2009

  • A Study of LY573636 in Patients With Metastatic Breast Cancer

    Condition:   Breast Cancer
    Intervention:   Drug: LY573636
    Sponsor:   Eli Lilly and Company
    Recruiting - verified November 2009

  • Safety of and Immune Response to the PENNVAX-B DNA Vaccine With and Without IL-12 in HIV-uninfected Adults

    Condition:   HIV Infections
    Interventions:   Biological: PENNVAX-B;   Biological: IL-12 DNA plasmids
    Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
    Recruiting - verified August 2009

  • A Phase 3b Study of Vernakalant Injection in Patients With Recent Onset Symptomatic Atrial Fibrillation (AF)

    Condition:   Atrial Fibrillation
    Interventions:   Drug: Vernakalant;   Drug: Placebo
    Sponsors:   Astellas Pharma Inc;   Cardiome Pharma
    Recruiting - verified November 2009

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