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Paid Clinical Trials in Pennsylvania

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  • A Randomized Double Blind Placebo Controlled Study of the Effect of Swallowed Beclomethasone Dipropionate on Inflammatory Markers in Adult Patients With Eosinophilic Esophagitis

    Condition:   Eosinophilic Esophagitis
    Interventions:   Drug: Beclomethasone dipropionate;   Drug: placebo
    Sponsor:   Penn State University
    Not yet recruiting - verified November 2009

  • Safety and Efficacy of a Glaucoma Drug Delivery System

    Conditions:   Open-Angle Glaucoma;   Ocular Hypertension
    Interventions:   Drug: bimatoprost;   Drug: bimatoprost;   Drug: Placebo
    Sponsor:   Vistakon Pharmaceuticals
    Recruiting - verified November 2009

  • Clinical Evaluation of a Multifocal Contact Lens on Symptomatic Patients

    Condition:   Presbyopia
    Interventions:   Device: Etafilcon A Multifocal Contact Lens;   Device: Etafilcon A Contact Lens
    Sponsors:   Vistakon;   Visioncare Research Ltd.
    Recruiting - verified November 2009

  • Fluorine F18-EF5 and Fludeoxyglucose F18 Positron Emission Tomography in Assessing Hypoxia and Glycolysis in Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer

    Condition:   Non-small Cell Lung Cancer
    Interventions:   Radiation: fludeoxyglucose F 18;   Radiation: Fluorine F 18 EF5;   Procedure: Positron emission tomography
    Sponsor:   Abramson Cancer Center of the University of Pennsylvania
    Recruiting - verified November 2009

  • Magnetic Resonance Imaging-Based Radiation Therapy and Cisplatin in Patients With Stage I, Stage II, Stage III, or Stage IV Cervical Cancer

    Condition:   Cervical Cancer
    Interventions:   Radiation: intracavitary balloon brachytherapy;   Radiation: external beam radiation therapy;   Radiation: intensity-modulated radiation therapy;   Radiation: radiation therapy treatment planning/simulation;   Radiation: 3-dimensional conformal radiation therapy;   Drug: Cisplatin
    Sponsor:   Abramson Cancer Center of the University of Pennsylvania
    Recruiting - verified November 2009

  • Clinical Evaluation of a Silicone Hydrogel Lens

    Condition:   Lotrafilcon A Contact Lens Use
    Intervention:  
    Sponsor:   Novartis
    Recruiting - verified November 2009

  • Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease

    Conditions:   Coronary Artery Disease;   Chronic Kidney Disease;   Hypovitaminosis D;   Secondary Hyperparathyroidism
    Interventions:   Drug: paricalcitol;   Drug: placebo
    Sponsors:   Thomas Jefferson University;   Abbott
    Recruiting - verified November 2009

  • A Phase IIb 78-week Study in Patients on a Basal Insulin +/- Metformin and/or Sulfonylurea and Are Not at Goal to Add BI 10773 vs. Placebo

    Condition:   Diabetes Mellitus, Type 2
    Intervention:   Drug: BI 10773
    Sponsor:   Boehringer Ingelheim Pharmaceuticals
    Recruiting - verified November 2009

  • AZD6244 in Treating Patients With Recurrent or Persistent Endometrial Cancer

    Condition:   Endometrial Cancer
    Interventions:   Drug: MEK inhibitor AZD6244;   Other: laboratory biomarker analysis
    Sponsors:   Gynecologic Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • BIBF 1120 or Placebo in Combination With Paclitaxel and Carboplatin in First Line Treatment of Ovarian Cancer

    Conditions:   Ovarian Neoplasms;   Peritoneal Neoplasms
    Interventions:   Drug: BIBF 1120;   Drug: Placebo
    Sponsor:   Boehringer Ingelheim Pharmaceuticals
    Not yet recruiting - verified November 2009

  • Ultrasound Visualization Versus Electrical Nerve Stimulation

    Condition:   Trauma to the Arm, Shoulder, Elbow, Forearm, or Hand
    Interventions:   Device: Ultrasound (Sonosite Titan T-shaped ultrasound probe);   Device: Electrical Nerve Stimulation (Stimuplex (B Braun) needle)
    Sponsors:   Allentown Anesthesia Associates;   SonoSite, Inc.
    Recruiting - verified November 2009

  • The Effects of Physiologic Oxygen Tension on Clinical In Vitro Fertilization Outcomes

    Conditions:   Pregnancy;   Infertility
    Interventions:   Procedure: Atmospheric oxygen tension;   Procedure: Physiologic oxygen tension
    Sponsors:   Yale University;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   University of Pennsylvania;   University of California, San Francisco;   University of Michigan;   Wayne State University
    Not yet recruiting - verified November 2009

  • Cixutumumab and Sorafenib Tosylate in Treating Patients With Advanced Liver Cancer

    Condition:   Liver Cancer
    Interventions:   Biological: cixutumumab;   Drug: sorafenib tosylate;   Other: laboratory biomarker analysis
    Sponsors:   California Cancer Consortium;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • A Study to Evaluate the Efficacy and Safety of Fluticasone Furoate (FF)/GW642444 Inhalation Powder in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

    Condition:   Pulmonary Disease, Chronic Obstructive
    Interventions:   Drug: GW642444 Inhalation Powder;   Drug: FF/GW642444 Inhalation Powder
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Varenicline Treatment for Smoking Cessation in Patients With Bipolar Disorder

    Conditions:   Smoking Cessation;   Bipolar Disorder
    Interventions:   Drug: Varenicline (Chantix);   Drug: Placebo
    Sponsors:   University of Pittsburgh;   National Institute of Mental Health (NIMH);   Pfizer
    Not yet recruiting - verified November 2009

  • CD3/CD28 Bead Activated T-Cells Following Chemo-Immunotherapy in Patients With Chronic Lymphocytic Leukemia

    Condition:   Chronic Lymphocytic Leukemia
    Intervention:   Biological: Infusion of CD3/CD28 stimulated T cells
    Sponsors:   University of Pennsylvania;   M.D. Anderson Cancer Center
    Recruiting - verified November 2009

  • Human Tumor Necrosis Factor Alpha (TNFa)-Induced Pre-B Cell Bone Marrow Emigrants

    Condition:   Rheumatoid Arthritis
    Intervention:   Drug: Etanercept
    Sponsors:   University of Pittsburgh;   Amgen
    Recruiting - verified November 2009

  • A Pharmacokinetic/Pharmacodynamic Study of Intravenous and Subcutaneous CDP6038 in Subjects With Rheumatoid Arthritis on Methotrexate

    Conditions:   Arthritis;   Rheumatoid Arthritis
    Interventions:   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Other: Placebo IV;   Other: Placebo SC
    Sponsor:   UCB, Inc.
    Recruiting - verified November 2009

  • Reduction of Night-time Blood Pressure in Pediatric Renal Transplant Recipients

    Conditions:   Non-dipper;   Nocturnal Hypertension
    Interventions:   Drug: Time change;   Drug: Enalapril, Isradapine, Propranolol
    Sponsors:   North Shore Long Island Jewish Health System;   Children's Hospital of Philadelphia
    Recruiting - verified November 2009

  • A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: tocilizumab;   Drug: methotrexate
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009

  • Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosis

    Condition:   Onychomycosis
    Interventions:   Drug: IDP-108;   Drug: Vehicle
    Sponsor:   Dow Pharmaceutical Sciences
    Not yet recruiting - verified November 2009

  • A Multi-center Study to Investigate the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of R7103 Following Repeated Inhalation in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease

    Condition:   COPD
    Intervention:   Drug: R7103
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009

  • Creighton Model Effectiveness, Intentions and Behaviors Assessment (CEIBA)

    Conditions:   Pregnancy;   Fertility
    Intervention:  
    Sponsors:   University of Utah;   Department of Health and Human Services
    Recruiting - verified November 2009

  • Study of A3309 in Patients With Chronic Idiopathic Constipation

    Conditions:   Constipation;   Chronic Constipation
    Intervention:   Drug: A3309
    Sponsor:   Albireo
    Recruiting - verified November 2009

  • A Study Of A Novel Compound For Excessive Daytime Sleepiness Associated With Narcolepsy

    Conditions:   Excessive Daytime Sleepiness;   Narcolepsy
    Interventions:   Drug: Placebo;   Drug: PF-03654746
    Sponsor:   Pfizer
    Recruiting - verified November 2009

  • Acupuncture and Gabapentin for Hot Flashes Among Breast Cancer Survivors

    Condition:   Hot Flashes
    Intervention:   Drug: Gabapentin
    Sponsor:   Abramson Cancer Center of the University of Pennsylvania
    Recruiting - verified October 2009

  • Study of Blood and Bone Marrow Samples in Patients With Chronic Myelogenous Leukemia Enrolled on a CALGB Clinical Trial

    Condition:   Leukemia
    Interventions:   Genetic: DNA analysis;   Genetic: Southern blotting;   Genetic: cytogenetic analysis;   Genetic: polymerase chain reaction
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Golimumab in Rheumatoid Arthritis Patients With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)

    Conditions:   Arthritis;   Arthritis, Rheumatoid;   Autoimmune Diseases
    Interventions:   Drug: golimumab;   Drug: golimumab or placebo;   Drug: golimumab or placebo
    Sponsors:   Centocor, Inc.;   Schering-Plough
    Recruiting - verified November 2009

  • Detection and Quant of Differences in Hodgkin Lymphoma and Diffuse Large B-cell Lymphoma Using Positron Emission Tomography/Computed Tomography (PET/CT)

    Condition:   Lymphoma
    Interventions:   Radiation: Fludeoxyglucose F18;   Procedure: Computed Tomography;   Procedure: Positron emission tomography
    Sponsor:   Abramson Cancer Center of the University of Pennsylvania
    Recruiting - verified October 2009

  • A Study to Evaluate the Safety and Tolerability of Rizatriptan for Long Term Treatment of Acute Migraine in Children and Adolescents

    Condition:   Acute Migraine With or Without Aura
    Intervention:   Drug: rizatriptan benzoate
    Sponsor:   Merck
    Recruiting - verified November 2009

  • A Safety, Tolerability, And Pharmacokinetic Trial With CVX-241 In Patients With Advanced Solid Tumors

    Condition:   Advanced Solid Tumors
    Interventions:   Drug: CVX-241;   Drug: CVX-241;   Drug: CVX-241;   Drug: CVX-241;   Drug: CVX-241;   Drug: CVX-241
    Sponsor:   Pfizer
    Not yet recruiting - verified November 2009

  • Allo-antibodies in Pediatric Heart Transplantation

    Condition:   Heart Transplantation
    Intervention:  
    Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   National Heart, Lung, and Blood Institute (NHLBI)
    Not yet recruiting - verified October 2009

  • A Dose Escalation Study in Adult Patients With Advanced Solid Malignancies

    Condition:   Solid Tumors
    Intervention:   Drug: BGJ398
    Sponsor:   Novartis Pharmaceuticals
    Not yet recruiting - verified October 2009

  • A Study to Evaluate the Efficacy and Tolerability of Rizatriptan for Treatment of Acute Migraine in Children and Adolescents

    Condition:   Acute Migraine With or Without Aura in Children and Adolescents.
    Interventions:   Drug: rizatriptan benzoate;   Drug: Comparator: Placebo
    Sponsor:   Merck
    Recruiting - verified November 2009

  • A Comparison of Peak Aqueous Penetration and PEG2 Inhibition of Acuvail, Xibrom, and Nevanac in Patients Undergoing Phacoemulsification

    Condition:   Cataracts
    Interventions:   Drug: Ketorolac Tromethamine 0.45%;   Drug: bromfenac 0.09%;   Drug: nepafenac 0.1%
    Sponsors:   Bucci Laser Vision Institute;   Allergan
    Recruiting - verified October 2009

  • Acute Graft-versus-Host Disease Treatment (BMT CTN 0802)

    Conditions:   Graft-Versus-Host Disease;   Immune System Disorders
    Interventions:   Drug: Mycophenolate Mofetil;   Drug: Placebo
    Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI);   Blood and Marrow Transplant Clinical Trials Newtwork (BMT CTN)
    Not yet recruiting - verified October 2009

  • Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma

    Conditions:   Lymphoma;   Lymphoproliferative Disorder
    Interventions:   Other: biologic sample preservation procedure;   Other: informational intervention
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Safety and Efficacy of Direct Blood Volume Measurement in the Treatment of Heart Failure

    Condition:   Heart Failure
    Interventions:   Other: Daxor Blood Volume Analysis;   Other: Clinical volume status assessment
    Sponsors:   New York University School of Medicine;   Daxor Corporation
    Not yet recruiting - verified October 2009

  • A Study of Duloxetine in Major Depressive Disorder (MDD) and Associated Painful Symptoms

    Condition:   Major Depressive Disorder
    Interventions:   Drug: Duloxetine;   Drug: Placebo
    Sponsor:   Eli Lilly and Company
    Not yet recruiting - verified November 2009

  • Neural Substrates in Nicotine Withdrawal

    Condition:   Tobacco Use Disorder
    Interventions:   Drug: Tolcapone;   Drug: Placebo
    Sponsors:   University of Pennsylvania;   National Institutes of Health (NIH)
    Not yet recruiting - verified October 2009

  • Safety and Efficacy Study in Subjects With Leber Congenital Amaurosis

    Condition:   Leber Congenital Amaurosis Due to RPE65 Mutations
    Intervention:   Biological: AAV2-hRPE65v2
    Sponsors:   Children's Hospital of Philadelphia;   University of Iowa
    Not yet recruiting - verified October 2009

  • CALIPSO: Calfactant for Acute Lung Injury in Pediatric Stem Cell Transplant and Oncology Patients

    Condition:   Acute Lung Injury
    Interventions:   Drug: Calfactant;   Other: Air placebo
    Sponsor:   Penn State University
    Not yet recruiting - verified October 2009

  • A Study to Evaluate the Efficacy and Safety of DR-103 for the Prevention of Pregnancy

    Condition:   Pregnancy Prevention
    Intervention:   Drug: DR-103
    Sponsor:   Teva Women's Health
    Recruiting - verified October 2009

  • Study of Bone Marrow and Blood Samples From Patients With Leukemia or Other Hematopoietic Cancers

    Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
    Interventions:   Genetic: cytogenetic analysis;   Genetic: fluorescence in situ hybridization
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI);   Eastern Cooperative Oncology Group
    Recruiting - verified November 2009

  • TAXUS Libertē Post Approval Study

    Condition:   Coronary Artery Disease
    Interventions:   Device: TAXUS Liberté Paclitaxel-Eluting Coronary Stent;   Drug: prasugrel;   Drug: placebo;   Drug: aspirin
    Sponsors:   Boston Scientific Corporation;   Eli Lilly and Company;   Daiichi Sankyo Inc.
    Not yet recruiting - verified November 2009

  • Efficacy and Safety Study of JTT-654 in Type 2 Diabetic Patients

    Condition:   Type II Diabetes Mellitus
    Interventions:   Drug: JTT-654;   Drug: JTT-654 Placebo
    Sponsor:   Akros Pharma Inc.
    Recruiting - verified November 2009

  • Post Approval Study of Coaptite® in the Treatment of Female Urinary Incontinence

    Condition:   Female Stress Urinary Incontinence Due to Intrinsic Sphincter Deficiency
    Intervention:   Device: Coaptite®
    Sponsor:   BioForm Medical, Inc.
    Recruiting - verified November 2009

  • Safety and Tolerability of TAK-491 Plus Chlorthalidone Compared to Olmesartan Medoxomil-Hydrochlorothiazide in Subjects With Essential Hypertension

    Condition:   Essential Hypertension
    Interventions:   Drug: TAK-491 and chlorthalidone;   Drug: Olmesartan medoxomil-hydrochlorothiazide
    Sponsor:   Takeda Global Research & Development Center, Inc.
    Recruiting - verified November 2009

  • Safety and Efficacy of Once-Daily KRP-104 in Type 2 Diabetic Patients That Cannot Control Their Diabetes on Metformin Alone

    Condition:   Type 2 Diabetes
    Interventions:   Drug: KRP-104;   Drug: Placebo
    Sponsors:   ActivX Biosciences, Inc.;   Kyorin Pharmaceutical Co.,Ltd
    Recruiting - verified October 2009

  • The Use of Certolizumab Pegol in Adult Subjects With Rheumatoid Arthritis to Assess the Antibody Response When Receiving Influenza Virus and Pneumococcal Vaccines

    Condition:   Rheumatoid Arthritis
    Interventions:   Biological: Placebo;   Biological: Certolizumab pegol
    Sponsor:   UCB, Inc.
    Recruiting - verified November 2009

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