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Paid Clinical Trials in Missouri

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  • Clinical Evaluation of a Multifocal Contact Lens on Symptomatic Patients

    Condition:   Presbyopia
    Interventions:   Device: Etafilcon A Multifocal Contact Lens;   Device: Etafilcon A Contact Lens
    Sponsors:   Vistakon;   Visioncare Research Ltd.
    Recruiting - verified November 2009

  • Evaluation of Treatment Satisfaction and Preference for Sumavel DosePro in the Treatment of Migraine

    Condition:   Migraine
    Intervention:   Device: Sumavel DosePro
    Sponsor:   Zogenix, Inc.
    Not yet recruiting - verified November 2009

  • Clinical Evaluation of a Silicone Hydrogel Lens

    Condition:   Lotrafilcon A Contact Lens Use
    Intervention:  
    Sponsor:   Novartis
    Recruiting - verified November 2009

  • Azacitidine and Lenalidomide for Acute Myeloid Leukemia

    Condition:   Leukemia, Myeloid, Acute
    Interventions:   Drug: Azacitidine and Lenalidomide;   Drug: Azacitidine and Lenalidomide;   Drug: Azacitidine and Lenalidomide;   Drug: Azacitidine and Lenalidomide
    Sponsor:   Washington University School of Medicine
    Not yet recruiting - verified November 2009

  • Intermittent Versus Continuous Pulse Oximetry Monitoring of Infants Admitted for Bronchiolitis

    Conditions:   Bronchiolitis;   Hypoxia
    Intervention:   Other: Pulse oximetry monitoring
    Sponsors:   Lifespan;   University of Missouri-Columbia
    Not yet recruiting - verified November 2009

  • A Four Week Study of Azithromycin Ophthalmic Solution, 1% Versus Placebo in Subjects With Dry Eye Disease

    Condition:   Dry Eye Disease
    Interventions:   Drug: Azithromycin Ophthalmic Solution, 1%;   Drug: Placebo
    Sponsor:   Inspire Pharmaceuticals
    Recruiting - verified November 2009

  • Clinical Study to Evaluate the Efficacy, Pharmacokinetics, and Safety of Immunoglobulin Intravenous (Human) 10% (NewGam) in Patients With Primary Immunodeficiency Diseases

    Condition:   Primary Immunodeficiency Diseases
    Interventions:   Biological: NewGam;   Biological: NewGam
    Sponsors:   Octapharma;   Premeir Research
    Recruiting - verified November 2009

  • A Phase IIb 78-week Study in Patients on a Basal Insulin +/- Metformin and/or Sulfonylurea and Are Not at Goal to Add BI 10773 vs. Placebo

    Condition:   Diabetes Mellitus, Type 2
    Intervention:   Drug: BI 10773
    Sponsor:   Boehringer Ingelheim Pharmaceuticals
    Recruiting - verified November 2009

  • AZD6244 in Treating Patients With Recurrent or Persistent Endometrial Cancer

    Condition:   Endometrial Cancer
    Interventions:   Drug: MEK inhibitor AZD6244;   Other: laboratory biomarker analysis
    Sponsors:   Gynecologic Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of Ataluren (PTC124®) in Nonambulatory Patients With Nonsense-Mutation-Mediated Duchenne/Becker Muscular Dystrophy (nmDMD/BMD)

    Conditions:   Duchenne Muscular Dystrophy;   Becker Muscular Dystrophy
    Intervention:   Drug: Ataluren (PTC124)
    Sponsors:   PTC Therapeutics;   Genzyme
    Not yet recruiting - verified November 2009

  • A Study to Evaluate the Efficacy and Safety of Fluticasone Furoate (FF)/GW642444 Inhalation Powder in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

    Condition:   Pulmonary Disease, Chronic Obstructive
    Interventions:   Drug: GW642444 Inhalation Powder;   Drug: FF/GW642444 Inhalation Powder
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Efficacy and Safety of Budesonide Foam for Patients With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis

    Conditions:   Proctitis;   Proctosigmoiditis
    Interventions:   Drug: Budesonide;   Drug: Placebo
    Sponsor:   Salix Pharmaceuticals
    Not yet recruiting - verified November 2009

  • A Comparison of Casting and Splinting in Pediatric Radial Buckle Fractures

    Condition:   Distal Radial Buckle Fractures
    Interventions:   Procedure: Volar Splint;   Procedure: Cast
    Sponsor:   Washington University School of Medicine
    Recruiting - verified November 2009

  • A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: tocilizumab;   Drug: methotrexate
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009

  • Alfentanil: Simultaneous Testing Pilot

    Condition:   To Evaluate Two Paradigms for Simultaneous Assessment of Hepatic and Intestinal CYP3A Activity
    Intervention:  
    Sponsor:   Washington University School of Medicine
    Recruiting - verified November 2009

  • Study Evaluating Two Dose Levels of Targetin Capsules in Patients With Refractory Cutaneous T-cell Lymphoma (CTCL)

    Condition:   Refractory Cutaneous T-cell Lymphoma
    Interventions:   Drug: bexarotene;   Drug: bexarotene
    Sponsor:   Eisai Inc.
    Not yet recruiting - verified November 2009

  • Creighton Model Effectiveness, Intentions and Behaviors Assessment (CEIBA)

    Conditions:   Pregnancy;   Fertility
    Intervention:  
    Sponsors:   University of Utah;   Department of Health and Human Services
    Recruiting - verified November 2009

  • Safety and Immunogenicity of Replication-Competent Adenovirus 4-vectored Vaccine for Avian Influenza H5N1

    Conditions:   Bird Flu;   Influenza
    Interventions:   Other: Placebo;   Biological: Ad4-H5-Vtn
    Sponsor:   PaxVax, Inc.
    Recruiting - verified November 2009

  • Comparison of Allogenix Plus Demineralized Bone Matrix and Autogenous Bone Dust Versus Autogenous Bone Dust Alone in Ossification of Small Calvarial Defects, a Pilot Study.

    Condition:   Metopic Craniosynostosis
    Intervention:   Biological: Allogenix Plus
    Sponsors:   University of Missouri-Columbia;   Biomet, Inc.
    Recruiting - verified October 2009

  • Genetics Informatics Trial of Warfarin to Prevent Deep Venous Thrombosis (DVT)

    Condition:   Thromboembolism
    Interventions:   Other: Pharmacogenetic Warfarin Initiation;   Other: Clinical Warfarin Initiation (non-pharmacogenetic)
    Sponsors:   Washington University School of Medicine;   Intermountain Health Care, Inc.;   University of Utah;   National Heart, Lung, and Blood Institute (NHLBI)
    Not yet recruiting - verified October 2009

  • Study of Bone Marrow and Blood Samples in Patients With Untreated Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia Enrolled on Clinical Trial CALGB-9621 or CALGB-9720

    Condition:   Leukemia
    Intervention:   Other: laboratory biomarker analysis
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of Biomarkers in Blood and Bone Marrow Samples From Patients With Previously Untreated Chronic Lymphocytic Leukemia

    Condition:   Leukemia
    Interventions:   Genetic: fluorescence in situ hybridization;   Genetic: mutation analysis;   Genetic: nucleic acid sequencing;   Genetic: polymerase chain reaction;   Genetic: western blotting;   Other: flow cytometry;   Other: laboratory biomarker analysis
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of Blood and Bone Marrow Samples in Patients With Chronic Myelogenous Leukemia Enrolled on a CALGB Clinical Trial

    Condition:   Leukemia
    Interventions:   Genetic: DNA analysis;   Genetic: Southern blotting;   Genetic: cytogenetic analysis;   Genetic: polymerase chain reaction
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • 64CuATSM and Hypoxia in Stage IIIB/IV Non-small Cell Lung Cancer With Carboplatin, Paclitaxel, and Bevacizumab

    Condition:   Carcinoma, Non-Small-Cell Lung
    Intervention:   Drug: 64Cu-ATSM PET
    Sponsor:   Washington University School of Medicine
    Not yet recruiting - verified October 2009

  • Reduced Intensity Transplant Conditioning Regimen for Severe Thalassemia

    Condition:   Severe Thalassemia
    Intervention:   Drug: Transplant conditioning regimen of alemtuzumab, fludarabine, and melphalan
    Sponsors:   Washington University School of Medicine;   New England Research Institutes;   Pediatric Blood and Marrow Transplant Consortium
    Not yet recruiting - verified October 2009

  • Allo-antibodies in Pediatric Heart Transplantation

    Condition:   Heart Transplantation
    Intervention:  
    Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   National Heart, Lung, and Blood Institute (NHLBI)
    Not yet recruiting - verified October 2009

  • Assessing the Safety/Efficacy of Asacol® Given Every 12 Hours to Children and Adolescents for the Maintenance of Remission of Ulcerative Colitis

    Condition:   Ulcerative Colitis
    Interventions:   Drug: Asacol (mesalamine), High Dose;   Drug: Asacol (mesalamine), Low Dose
    Sponsor:   Procter and Gamble
    Recruiting - verified October 2009

  • Acute Graft-versus-Host Disease Treatment (BMT CTN 0802)

    Conditions:   Graft-Versus-Host Disease;   Immune System Disorders
    Interventions:   Drug: Mycophenolate Mofetil;   Drug: Placebo
    Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI);   Blood and Marrow Transplant Clinical Trials Newtwork (BMT CTN)
    Not yet recruiting - verified October 2009

  • Collecting and Storing Blood Samples From Patients With Previously Untreated Non-Hodgkin Lymphoma

    Condition:   Lymphoma
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma

    Conditions:   Lymphoma;   Lymphoproliferative Disorder
    Interventions:   Other: biologic sample preservation procedure;   Other: informational intervention
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Preventative Osteopathic Manipulative Treatment (OMT) and the Nursing Home Patient

    Condition:   General Health Status
    Interventions:   Procedure: Osteopathic Manipulative Treatment;   Procedure: Light Touch
    Sponsor:   A.T. Still University of Health Sciences
    Recruiting - verified October 2009

  • EPOCH Chemotherapy and Bortezomib for Associated T-Cell Leukemia Lymphoma

    Condition:   Leukemia-Lymphoma, Adult T-Cell
    Intervention:   Drug: Etoposide, Vincristine, Doxorubicin, Prednisone, Cyclophosphamide (EPOCH) with Bortezomib and Raltegravir
    Sponsor:   Washington University School of Medicine
    Not yet recruiting - verified October 2009

  • Intravenous (IV) Decitabine and Oral Bexarotene for Acute Myelogenous Leukemia (AML)

    Condition:   Leukemia, Myeloid, Acute
    Interventions:   Drug: Decitabine and Bexarotene;   Drug: Decitabine and Bexarotene;   Drug: Decitabine and Bexarotene
    Sponsor:   Washington University School of Medicine
    Not yet recruiting - verified October 2009

  • Study of Bone Marrow and Blood Samples From Patients With Leukemia or Other Hematopoietic Cancers

    Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
    Interventions:   Genetic: cytogenetic analysis;   Genetic: fluorescence in situ hybridization
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI);   Eastern Cooperative Oncology Group
    Recruiting - verified November 2009

  • A Study to Evaluate the Efficacy and Safety of DR-103 for the Prevention of Pregnancy

    Condition:   Pregnancy Prevention
    Intervention:   Drug: DR-103
    Sponsor:   Teva Women's Health
    Recruiting - verified October 2009

  • TAXUS Libertē Post Approval Study

    Condition:   Coronary Artery Disease
    Interventions:   Device: TAXUS Liberté Paclitaxel-Eluting Coronary Stent;   Drug: prasugrel;   Drug: placebo;   Drug: aspirin
    Sponsors:   Boston Scientific Corporation;   Eli Lilly and Company;   Daiichi Sankyo Inc.
    Not yet recruiting - verified November 2009

  • Post Approval Study of Coaptite® in the Treatment of Female Urinary Incontinence

    Condition:   Female Stress Urinary Incontinence Due to Intrinsic Sphincter Deficiency
    Intervention:   Device: Coaptite®
    Sponsor:   BioForm Medical, Inc.
    Recruiting - verified November 2009

  • Safety and Tolerability of TAK-491 Plus Chlorthalidone Compared to Olmesartan Medoxomil-Hydrochlorothiazide in Subjects With Essential Hypertension

    Condition:   Essential Hypertension
    Interventions:   Drug: TAK-491 and chlorthalidone;   Drug: Olmesartan medoxomil-hydrochlorothiazide
    Sponsor:   Takeda Global Research & Development Center, Inc.
    Recruiting - verified November 2009

  • The Use of Certolizumab Pegol in Adult Subjects With Rheumatoid Arthritis to Assess the Antibody Response When Receiving Influenza Virus and Pneumococcal Vaccines

    Condition:   Rheumatoid Arthritis
    Interventions:   Biological: Placebo;   Biological: Certolizumab pegol
    Sponsor:   UCB, Inc.
    Recruiting - verified November 2009

  • H1N1 Vaccine at Two Dose Levels in HIV Positive Adults

    Condition:   Influenza
    Intervention:   Biological: Inactivated Influenza H1N1 vaccine
    Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
    Recruiting - verified October 2009

  • Novartis H1N1 Vaccine in Pregnant Women

    Condition:   Influenza
    Intervention:   Biological: Inactivated H1N1 Vaccine
    Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
    Recruiting - verified November 2009

  • Study of Plerixafor Combined With Cytarabine and Daunorubicin in Patients With De Novo Acute Myeloid Leukemia

    Condition:   De Novo Acute Myeloid Leukemia
    Intervention:   Drug: Plerixafor
    Sponsor:   Genzyme
    Recruiting - verified October 2009

  • A Phase 3b Study of Vernakalant Injection in Patients With Recent Onset Symptomatic Atrial Fibrillation (AF)

    Condition:   Atrial Fibrillation
    Interventions:   Drug: Vernakalant;   Drug: Placebo
    Sponsors:   Astellas Pharma Inc;   Cardiome Pharma
    Recruiting - verified November 2009

  • A Study of YM155 Plus Rituximab in Subjects With Non-Hodgkin's Lymphoma Who Have Received Prior Treatment

    Condition:   Non-Hodgkin's Lymphoma
    Interventions:   Drug: YM155;   Biological: Rituximab
    Sponsor:   Astellas Pharma Inc
    Recruiting - verified November 2009

  • Nexavar® Versus Placebo in Locally Advance RAI-Refractory Differentiated Thyroid Cancer

    Condition:   Thyroid Neoplasm
    Interventions:   Drug: Nexavar (Sorafenib, BAY43-9006);   Drug: Placebo
    Sponsors:   Bayer;   Onyx
    Recruiting - verified November 2009

  • Dapagliflozin DPPIV Inhibitor add-on Study

    Condition:   Type 2 Diabetes
    Interventions:   Drug: Dapagliflozin;   Drug: Placebo
    Sponsors:   AstraZeneca;   Bristol-Myers Squibb
    Recruiting - verified November 2009

  • Study to Assess the Immunogenicity and Safety of an Investigational Influenza Vaccine in Children

    Condition:   Influenza Infection
    Interventions:   Biological: GSK investigational vaccine GSK1557482A;   Biological: Fluzone®
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

    Conditions:   Brain and Central Nervous System Tumors;   Neurotoxicity
    Interventions:   Drug: temozolomide;   Radiation: 3-dimensional conformal radiation therapy;   Radiation: intensity-modulated radiation therapy
    Sponsors:   Eastern Cooperative Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study in Adolescents With Schizophrenia or Bipolar Disorder

    Conditions:   Bipolar I Disorder;   Schizophrenia
    Interventions:   Drug: Olanzapine;   Behavioral: Standard behavioral weight intervention;   Behavioral: Intense behavioral weight intervention
    Sponsor:   Eli Lilly and Company
    Recruiting - verified November 2009

  • The Dual Antiplatelet Therapy Study (DAPT Study)

    Condition:   Coronary Artery Disease
    Interventions:   Drug: Placebo & Aspirin;   Drug: Clopidogrel & Aspirin, Prasugrel & Aspirin
    Sponsors:   Harvard Clinical Research Institute;   Abbott;   Boston Scientific Corporation;   Bristol-Myers Squibb;   Sanofi-Synthelabo;   Cordis Corporation;   Eli Lilly and Company;   Daiichi Sankyo Inc.;   Medtronic
    Recruiting - verified November 2009

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