Find Paid Clinical Trials in Massachusetts

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Paid Clinical Trials in Massachusetts

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  • Study of the Impact of Parental Note Taking on the Effectiveness of Anticipatory Guidance

    Conditions:   Health Education;   Sudden Infant Death
    Intervention:   Behavioral: Note taking
    Sponsors:   Boston Medical Center;   The Joel and Barbara Alpert Endowment For The Children of The City
    Not yet recruiting - verified November 2009

  • Postoperative Pain After Pediatric Umbilical Hernia Repair

    Condition:   Pediatric Postoperative Pain
    Interventions:   Procedure: bilateral ultrasound-guided rectus sheath block;   Procedure: Wound infiltration
    Sponsors:   Children's Hospital Boston;   Harvard Catalyst Pilot Grant;   The Harvard Clinical and Translational Science Center
    Recruiting - verified November 2009

  • Prospective Observational Long-term Safety Registry of Multiple Sclerosis Patients Who Have Participated in Cladribine Clinical Trials

    Condition:   Multiple Sclerosis
    Intervention:  
    Sponsor:   EMD Serono
    Recruiting - verified November 2009

  • The Biology of Resilience

    Condition:   Stress Response
    Interventions:   Drug: intranasal oxytocin;   Drug: Placebo;   Behavioral: Social support;   Behavioral: No Social Support;   Other: Female gender;   Other: Male Gender
    Sponsors:   Harvard School of Public Health;   Brigham and Women's Hospital
    Recruiting - verified November 2009

  • Genetic Mechanisms in Human Hypertension Renin-angiotensin-aldosterone System (RAAS) Inhibition Study

    Condition:   Hypertension
    Intervention:   Drug: Lisinopril, Atenolol
    Sponsors:   Brigham and Women's Hospital;   University of Utah
    Recruiting - verified November 2009

  • ABT-888 and Temozolomide for Metastatic Breast Cancer

    Conditions:   Breast Cancer;   Metastatic Breast Cancer
    Interventions:   Drug: ABT-888;   Drug: temozolomide
    Sponsors:   Massachusetts General Hospital;   Dana-Farber Cancer Institute;   Beth Israel Deaconess Medical Center;   Abbott
    Recruiting - verified November 2009

  • Harnessing Placebo Effects: Non-Deceptive Use of Placebo in Irritable Bowel Syndrome (IBS)

    Condition:   Irritable Bowel Syndrome
    Intervention:   Other: Sugar pill
    Sponsors:   Harvard University Faculty of Medicine;   Beth Israel Deaconess Medical Center
    Recruiting - verified November 2009

  • Study Evaluating the Efficacy and Safety of SBI-087 in Seropositive Subjects With Active Rheumatoid Arthritis

    Condition:   Active Rheumatoid Arthritis
    Intervention:   Drug: SBI-087
    Sponsor:   Wyeth
    Recruiting - verified November 2009

  • Study of Ataluren (PTC124®) in Nonambulatory Patients With Nonsense-Mutation-Mediated Duchenne/Becker Muscular Dystrophy (nmDMD/BMD)

    Conditions:   Duchenne Muscular Dystrophy;   Becker Muscular Dystrophy
    Intervention:   Drug: Ataluren (PTC124)
    Sponsors:   PTC Therapeutics;   Genzyme
    Not yet recruiting - verified November 2009

  • A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: tocilizumab;   Drug: methotrexate
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009

  • Assessment of Insulin Resistance, NAFLD, Predictors of CV Morbidity, and Subcutaneous Adipose and Visceral Adipose Gene Expression in Patients Undergoing Gastric Bypass Surgery

    Conditions:   Morbid Obesity;   Insulin Resistance;   Non-Alcoholic Fatty Liver Disease
    Intervention:  
    Sponsors:   University of Massachusetts;   Worcester Foundation for Biomedical Research
    Recruiting - verified November 2009

  • Comprehensive Collection, Charting, and Communication System

    Condition:   Autism
    Intervention:  
    Sponsors:   SymTrend Inc.;   University of Washington;   National Institute of Mental Health (NIMH)
    Recruiting - verified October 2009

  • Study of Blood and Bone Marrow Samples in Patients With Chronic Myelogenous Leukemia Enrolled on a CALGB Clinical Trial

    Condition:   Leukemia
    Interventions:   Genetic: DNA analysis;   Genetic: Southern blotting;   Genetic: cytogenetic analysis;   Genetic: polymerase chain reaction
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Vitamin D Supplementation in Psychiatric Illnesses

    Conditions:   Obesity;   Vitamin D Deficiency;   Psychosis;   Schizophrenia;   Schizoaffective Disorder
    Intervention:   Drug: Ergocalciferols
    Sponsor:   University of Massachusetts
    Recruiting - verified October 2009

  • Carboplatin and Bevacizumab for Progressive Breast Cancer Brain Metastases

    Conditions:   Metastatic Breast Cancer;   Breast Cancer;   Progressive Breast Cancer
    Interventions:   Drug: carboplatin;   Drug: bevacizumab;   Drug: herceptin
    Sponsors:   Dana-Farber Cancer Institute;   Brigham and Women's Hospital;   Massachusetts General Hospital;   Beth Israel Deaconess Medical Center;   Genentech
    Recruiting - verified October 2009

  • A Study to Evaluate the Safety and Tolerability of Rizatriptan for Long Term Treatment of Acute Migraine in Children and Adolescents

    Condition:   Acute Migraine With or Without Aura
    Intervention:   Drug: rizatriptan benzoate
    Sponsor:   Merck
    Recruiting - verified November 2009

  • Assessing the Safety/Efficacy of Asacol® Given Every 12 Hours to Children and Adolescents for the Maintenance of Remission of Ulcerative Colitis

    Condition:   Ulcerative Colitis
    Interventions:   Drug: Asacol (mesalamine), High Dose;   Drug: Asacol (mesalamine), Low Dose
    Sponsor:   Procter and Gamble
    Recruiting - verified October 2009

  • Allo-antibodies in Pediatric Heart Transplantation

    Condition:   Heart Transplantation
    Intervention:  
    Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   National Heart, Lung, and Blood Institute (NHLBI)
    Not yet recruiting - verified October 2009

  • Phosphate Kinetic Modeling

    Conditions:   End Stage Renal Disease;   Hyperphosphatemia
    Intervention:   Other: Computer algorithm management of hyperphosphatemia
    Sponsor:   Fresenius Medical Care North America
    Recruiting - verified October 2009

  • ActiveStep Comparative Effectiveness Trial

    Condition:   Balance
    Interventions:   Device: ActiveStep Treadmill;   Other: Physical Therapy
    Sponsor:   Dartmouth-Hitchcock Medical Center
    Not yet recruiting - verified November 2009

  • Evaluating an Emergency Department Observation Syncope Protocol for Older Adults

    Condition:   Syncope
    Interventions:   Other: Emergency Department Observation Protocol;   Other: Unstructured, inpatient evaluation
    Sponsors:   University of California, Los Angeles;   University of Southern California;   Brigham and Women's Hospital
    Not yet recruiting - verified October 2009

  • SprayShield EU Post Market Study

    Conditions:   Ulcerative Colitis;   Familial Polyposis
    Interventions:   Device: SprayShield Adhesion Barrier System;   Procedure: Good Surgical Technique Alone
    Sponsor:   Confluent Surgical
    Recruiting - verified October 2009

  • Cognitive-Behavioral Therapy for Pediatric Body Dysmorphic Disorder

    Condition:   Body Dysmorphic Disorder
    Intervention:   Behavioral: Cognitive-Behavioral Therapy
    Sponsor:   Massachusetts General Hospital
    Recruiting - verified October 2009

  • Computer-Based Alcohol Use Disorder Recovery System

    Condition:   Alcohol Dependence
    Intervention:   Behavioral: Addiction CHESS
    Sponsors:   University of Wisconsin, Madison;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Not yet recruiting - verified October 2009

  • The Effect of Food (High Fat and Low Fat Breakfast) on the Pharmacokinetics of Regorafenib

    Conditions:   Dietary Fats;   Pharmacokinetics
    Interventions:   Drug: Regorafenib (BAY73-4506);   Drug: Regorafenib (BAY73-4506);   Drug: Regorafenib (BAY73-4506)
    Sponsor:   Bayer
    Not yet recruiting - verified October 2009

  • Acute Graft-versus-Host Disease Treatment (BMT CTN 0802)

    Conditions:   Graft-Versus-Host Disease;   Immune System Disorders
    Interventions:   Drug: Mycophenolate Mofetil;   Drug: Placebo
    Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI);   Blood and Marrow Transplant Clinical Trials Newtwork (BMT CTN)
    Not yet recruiting - verified October 2009

  • Assess the Ability of Electrical Cardiometry to Trend Hemodynamic Variables During Dexmedetomidine Sedation

    Conditions:   Cardiac Output;   Sedation
    Intervention:  
    Sponsor:   Children's Hospital Boston
    Recruiting - verified October 2009

  • A Study to Evaluate the Efficacy and Tolerability of Rizatriptan for Treatment of Acute Migraine in Children and Adolescents

    Condition:   Acute Migraine With or Without Aura in Children and Adolescents.
    Interventions:   Drug: rizatriptan benzoate;   Drug: Comparator: Placebo
    Sponsor:   Merck
    Recruiting - verified November 2009

  • Safety and Dose Determining Multi-dose Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma

    Condition:   Multiple Myeloma
    Intervention:   Drug: BT062
    Sponsors:   Biotest Pharmaceuticals Corporation;   Biotest
    Not yet recruiting - verified October 2009

  • Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma

    Conditions:   Lymphoma;   Lymphoproliferative Disorder
    Interventions:   Other: biologic sample preservation procedure;   Other: informational intervention
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Safety and Efficacy Trial of Danazol in Patients With Fanconi Anemia or Dyskeratosis Congenita

    Conditions:   Fanconi Anemia;   Dyskeratosis Congenita
    Intervention:   Drug: danazol
    Sponsor:   Children's Hospital Boston
    Not yet recruiting - verified October 2009

  • A Pharmacokinetic Study of RO5185426 in Combination With a Drug Cocktail in Patients With Metastatic Melanoma

    Condition:   Malignant Melanoma
    Interventions:   Drug: RO5185426;   Drug: Drug cocktail
    Sponsor:   Hoffmann-La Roche
    Not yet recruiting - verified October 2009

  • Efficacy of Vorinostat to Induce Fetal Hemoglobin in Adults With Severe Sickle Cell Disease Who Have Failed Prior Therapy

    Condition:   Sickle Cell Disease
    Intervention:   Drug: vorinostat
    Sponsors:   Dana-Farber Cancer Institute;   Brigham and Women's Hospital;   Children's Hospital Boston;   Merck
    Not yet recruiting - verified October 2009

  • Cultivating Healthy Environments in Families With Type 1 Diabetes (CHEF)

    Condition:   Type I Diabetes
    Interventions:   Behavioral: Education;   Device: CGM;   Behavioral: Problem Solving;   Behavioral: Social Learning;   Behavioral: Behavior Modification
    Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Recruiting - verified August 2009

  • Restoring Sleep Homeostasis to Lower Blood Pressure

    Conditions:   Hypertension;   Pre-Hypertension
    Intervention:   Behavioral: Sleep extension
    Sponsor:   Beth Israel Deaconess Medical Center
    Recruiting - verified November 2009

  • Study to Assess VB-201 in Patients With Psoriasis

    Condition:   Active Plaque Psoriasis
    Interventions:   Drug: VB-201;   Drug: VB-201;   Other: Placebo
    Sponsor:   Vascular Biogenics, Ltd
    Not yet recruiting - verified October 2009

  • Study of Bone Marrow and Blood Samples From Patients With Leukemia or Other Hematopoietic Cancers

    Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
    Interventions:   Genetic: cytogenetic analysis;   Genetic: fluorescence in situ hybridization
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI);   Eastern Cooperative Oncology Group
    Recruiting - verified November 2009

  • Efficacy and Safety Study of JTT-654 in Type 2 Diabetic Patients

    Condition:   Type II Diabetes Mellitus
    Interventions:   Drug: JTT-654;   Drug: JTT-654 Placebo
    Sponsor:   Akros Pharma Inc.
    Recruiting - verified November 2009

  • Safety and Efficacy of AIN457 in Behçet's Patients With Posterior or Panuveitis

    Condition:   Behcet Disease
    Interventions:   Biological: AIN457;   Biological: AIN457;   Biological: Placebo
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified November 2009

  • A Weight Loss Study in Overweight Men and Women

    Condition:   Obesity
    Interventions:   Drug: LY377604;   Drug: Sibutramine;   Drug: Metoprolol XL;   Drug: Placebo sibutramine;   Drug: Placebo Metoprolol XL;   Drug: Placebo LY377604
    Sponsor:   Eli Lilly and Company
    Recruiting - verified November 2009

  • Effects of the Atkins Diet Versus a Low Fat Diet on Endothelial Function, Lipid Profiles, and Systemic Markers of Inflammation

    Conditions:   Cardiovascular Health;   Obesity
    Interventions:   Dietary Supplement: Low-Carbohydrate (Modified Atkins) Diet;   Dietary Supplement: Low-Fat (Heart Healthy) Diet
    Sponsors:   Boston Medical Center;   Robert C. Atkins Foundation
    Recruiting - verified November 2009

  • Safety of and Immune Response to an H1N1 Influenza Virus Vaccine in HIV Infected Children and Youth

    Conditions:   HIV Infections;   H1N1 Influenza Virus
    Intervention:   Biological: Influenza A (H1N1) 2009 monovalent vaccine
    Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
    Not yet recruiting - verified October 2009

  • Safety of and Immune Response to an H1N1 Influenza Vaccine in HIV Infected Pregnant Women

    Conditions:   HIV Infections;   H1N1 Influenza Virus
    Intervention:   Biological: Influenza A (H1N1) monovalent vaccine
    Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
    Recruiting - verified October 2009

  • Red Cell Storage Duration Study

    Conditions:   Cardiac Surgery;   Erythrocyte Transfusion
    Interventions:   Biological: Red blood cell units stored <= 10 days;   Biological: Red blood cell units stored >= 21 days
    Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
    Not yet recruiting - verified October 2009

  • Study of Plerixafor Combined With Cytarabine and Daunorubicin in Patients With De Novo Acute Myeloid Leukemia

    Condition:   De Novo Acute Myeloid Leukemia
    Intervention:   Drug: Plerixafor
    Sponsor:   Genzyme
    Recruiting - verified October 2009

  • A Phase 3b Study of Vernakalant Injection in Patients With Recent Onset Symptomatic Atrial Fibrillation (AF)

    Condition:   Atrial Fibrillation
    Interventions:   Drug: Vernakalant;   Drug: Placebo
    Sponsors:   Astellas Pharma Inc;   Cardiome Pharma
    Recruiting - verified November 2009

  • Effects of the V1a Agonist FE 202158 in Patients With Septic Shock

    Condition:   Septic Shock
    Interventions:   Drug: FE 202158;   Drug: Sodium Chloride
    Sponsor:   Ferring Pharmaceuticals
    Not yet recruiting - verified October 2009

  • HIV Testing in the Emergency Department at Baystate Medical Center: A Pilot Program

    Condition:   HIV Infections
    Intervention:  
    Sponsors:   Baystate Medical Center;   Massachusetts Department of Health
    Recruiting - verified September 2009

  • Observational Study to Assess Natural History in Cockayne Syndrome Patients

    Condition:   Cockayne Syndrome
    Intervention:  
    Sponsor:   DNage B.V.
    Recruiting - verified November 2009

  • Nexavar® Versus Placebo in Locally Advance RAI-Refractory Differentiated Thyroid Cancer

    Condition:   Thyroid Neoplasm
    Interventions:   Drug: Nexavar (Sorafenib, BAY43-9006);   Drug: Placebo
    Sponsors:   Bayer;   Onyx
    Recruiting - verified November 2009

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