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Paid Clinical Trials in Maryland

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  • Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy Patients

    Condition:   Moderate to Severe Postoperative Pain
    Interventions:   Drug: Q8003;   Drug: Morphine sulfate;   Drug: Oxycodone HCl
    Sponsor:   QRxPharma Inc.
    Not yet recruiting - verified November 2009

  • Dynamic Magnetic Resonance Imaging (MRI) for Lung Tumor Motion and Lung Function

    Condition:   Lung Cancer
    Intervention:  
    Sponsors:   University of Maryland;   National Institutes of Health (NIH)
    Not yet recruiting - verified November 2009

  • Safety and Tolerability of the Ketogenic Diet in Amyotrophic Lateral Sclerosis (ALS)

    Condition:   Amyotrophic Lateral Sclerosis
    Intervention:   Dietary Supplement: KetoCal
    Sponsors:   Johns Hopkins University;   Nutricia North America;   Cornell University
    Recruiting - verified November 2009

  • Preoperative Accelerated Partial Breast Irradiation (APBI) for Women With Stage I and Select IIA Breast Cancer

    Condition:   Breast Cancer
    Intervention:   Other: Phase II - Preoperative Radiation followed by Lumpectomy.
    Sponsor:   University of Maryland
    Recruiting - verified November 2009

  • A Study of the Safety and Pharmacokinetics of AGS-8M4 Given in Combination With Chemotherapy in Women With Ovarian Cancer

    Conditions:   Carcinoma;   Ovarian Cancer;   Ovarian Diseases;   Ovarian Neoplasms
    Interventions:   Biological: AGS-8M4;   Drug: Pegylated liposomal doxorubicin (PLD);   Drug: gemcitabine;   Drug: carboplatin
    Sponsors:   Astellas Pharma Inc;   Agensys, Inc.
    Recruiting - verified November 2009

  • Building Adherence to Live With And Navigate my Cystic Fibrosis (CF) Experience

    Condition:   Cystic Fibrosis
    Intervention:   Behavioral: Motivational Interviewing
    Sponsors:   Johns Hopkins University;   National Heart, Lung, and Blood Institute (NHLBI)
    Recruiting - verified November 2009

  • Doxycycline Outcomes in Lupus Erythematosus: (DOLE)

    Condition:   Cardiovascular Disease
    Interventions:   Drug: Doxycycline;   Drug: Doxycycline
    Sponsor:   Johns Hopkins University
    Not yet recruiting - verified November 2009

  • Developmental and Augmented Intervention for Facilitating Expressive Language

    Conditions:   Joint Engagement;   Enhanced Milieu Training;   Augmentative Communication (AAC)
    Intervention:   Behavioral: JAE Intervention
    Sponsors:   Autism Speaks;   Hugo W. Moser Research Institute at Kennedy Krieger, Inc.;   Vanderbilt University;   University of California, Los Angeles
    Recruiting - verified November 2009

  • Parents With Bipolar Disorder: Relationship of Adaptation to Own Illness With Risk Perception and Coping With Perceived Risk to a Child

    Condition:   Bipolar Disorder
    Intervention:  
    Sponsor:   National Human Genome Research Institute (NHGRI)
    Recruiting - verified October 2009

  • Internal Monitoring of Eye Movement in Schizophrenia

    Condition:   Schizophrenia
    Intervention:  
    Sponsor:   National Eye Institute (NEI)
    Recruiting - verified October 2009

  • Study of Peer Relationships at School

    Condition:   Autism
    Intervention:   Behavioral: SKILLS vs ENGAGE
    Sponsors:   Health Resources and Services Administration (HRSA);   Florida State University;   Johns Hopkins University;   University of Michigan;   University of Washington
    Recruiting - verified November 2009

  • A Phase IIb 78-week Study in Patients on a Basal Insulin +/- Metformin and/or Sulfonylurea and Are Not at Goal to Add BI 10773 vs. Placebo

    Condition:   Diabetes Mellitus, Type 2
    Intervention:   Drug: BI 10773
    Sponsor:   Boehringer Ingelheim Pharmaceuticals
    Recruiting - verified November 2009

  • The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise

    Conditions:   Herpesvirus;   Adenovirus;   Cytomegalovirus;   Human Papillomavirus;   Human Polyomavirus;   Respiratory Viruses
    Intervention:  
    Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
    Recruiting - verified October 2009

  • Evaluate the Safety of MN-221 in Subjects With Stable Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

    Condition:   Chronic Obstructive Pulmonary Disease
    Interventions:   Drug: MN-221 (Dose Group 1);   Drug: MN-221 (Dose Group 2);   Drug: MN-221 (Dose Group 3)
    Sponsor:   MediciNova
    Recruiting - verified November 2009

  • Muscle Derived Cell Therapy for Bladder Exstrophy Epispadias Induced Incontinence

    Conditions:   Bladder Exstrophy;   Urinary Incontinence
    Intervention:   Drug: MDC
    Sponsor:   Johns Hopkins University
    Not yet recruiting - verified November 2009

  • Ascending Dose Study of the Safety and Tolerability of REGN668 in Normal Healthy Volunteers

    Condition:   Healthy
    Intervention:   Biological: REGN668
    Sponsors:   Regeneron Pharmaceuticals;   Sanofi-Aventis
    Recruiting - verified November 2009

  • An Adhesion Reduction Plan in the Management of the Surgical Open Abdomen

    Condition:   Open Abdomen
    Intervention:   Procedure: Adhesion Reduction Plan
    Sponsors:   University of Maryland;   Genzyme
    Not yet recruiting - verified November 2009

  • Class 3 Biowaivers

    Condition:   Healthy
    Intervention:   Drug: cimetidine (or acyclovir)
    Sponsors:   University of Maryland;   Food and Drug Administration (FDA)
    Recruiting - verified November 2009

  • Early Intervention for Minority and Underserved Toddlers With Autism Spectrum Disorder (ASD)

    Condition:   Autism Spectrum Disorder
    Interventions:   Behavioral: Social Communication;   Behavioral: Social communication
    Sponsors:   Johns Hopkins University;   HRSA/Maternal and Child Health Bureau
    Recruiting - verified November 2009

  • To Demonstrate Superiority of Decitabine Over Azacitidine in Subjects With Intermediate- or High-risk MDS.

    Condition:   Myelodysplastic Syndromes
    Interventions:   Drug: decitabine;   Drug: azacitidine
    Sponsor:   Eisai Inc.
    Not yet recruiting - verified November 2009

  • Efficacy and Safety of Budesonide Foam for Patients With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis

    Conditions:   Proctitis;   Proctosigmoiditis
    Interventions:   Drug: Budesonide;   Drug: Placebo
    Sponsor:   Salix Pharmaceuticals
    Not yet recruiting - verified November 2009

  • Identification of the Pericardiophrenic Vein During Cardiac Device Implant Procedures to Prevent Extracardiac Stimulation

    Condition:   Heart Failure
    Intervention:  
    Sponsor:   Cardiac Concepts, Inc.
    Recruiting - verified November 2009

  • Efficacy and Safety of Budesonide Foam for Patients With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis

    Conditions:   Proctitis;   Proctosigmoiditis
    Interventions:   Drug: Budesonide;   Drug: Placebo
    Sponsor:   Salix Pharmaceuticals
    Not yet recruiting - verified November 2009

  • Partners for Better Health in Adolescent Type 2 Diabetes: The Buddy Study

    Conditions:   Obesity;   Diabetes Mellitus, Type 2;   Abnormal Glucose Metabolism;   Type 2 Diabetes
    Intervention:   Behavioral: Assignment of a Lay Patient Partner
    Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    Recruiting - verified September 2009

  • A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: tocilizumab;   Drug: methotrexate
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009

  • Study of A3309 in Patients With Chronic Idiopathic Constipation

    Conditions:   Constipation;   Chronic Constipation
    Intervention:   Drug: A3309
    Sponsor:   Albireo
    Recruiting - verified November 2009

  • Safety of Dexmedetomidine in Severe Traumatic Brain Injury

    Condition:   Traumatic Brain Injury
    Interventions:   Drug: Precedex;   Drug: Propofol;   Drug: Fentanyl;   Drug: Propofol
    Sponsors:   University of Maryland;   Hospira, Inc.
    Not yet recruiting - verified November 2009

  • Energy Value of Macronutrients From Almonds and Mechanisms of Nutrient Action

    Condition:   Healthy
    Interventions:   Other: 1.5PD almonds;   Other: 3.0PD almonds;   Other: Base (without almonds)
    Sponsor:   USDA and Almond Board of California
    Not yet recruiting - verified November 2009

  • Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

    Conditions:   Neuroendocrine Neoplasms;   Thyroid Neoplasms;   Parathyroid Neoplasms;   Adrenal Neoplasm;   Neuroblastoma
    Intervention:  
    Sponsor:   National Cancer Institute (NCI)
    Recruiting - verified September 2009

  • Recording and Modulation of Neuronal Mechanisms During Operant Conditioning: a MEG Study

    Condition:   Central Nervous System
    Intervention:  
    Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
    Recruiting - verified September 2009

  • Study of Blood and Bone Marrow Samples in Patients With Chronic Myelogenous Leukemia Enrolled on a CALGB Clinical Trial

    Condition:   Leukemia
    Interventions:   Genetic: DNA analysis;   Genetic: Southern blotting;   Genetic: cytogenetic analysis;   Genetic: polymerase chain reaction
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of Biomarkers in Blood and Bone Marrow Samples From Patients With Previously Untreated Chronic Lymphocytic Leukemia

    Condition:   Leukemia
    Interventions:   Genetic: fluorescence in situ hybridization;   Genetic: mutation analysis;   Genetic: nucleic acid sequencing;   Genetic: polymerase chain reaction;   Genetic: western blotting;   Other: flow cytometry;   Other: laboratory biomarker analysis
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Patterned Functional Electrical Stimulation (FES) Ergometry of Arm and Shoulder in Individuals With Spinal Cord Injury

    Condition:   Spinal Cord Injury
    Interventions:   Device: Non-FES Upper Extremity Exercise;   Device: RT300-SLSA, from Restorative Therapies, Inc.
    Sponsors:   Hugo W. Moser Research Institute at Kennedy Krieger, Inc.;   U.S. Army Medical Research and Materiel Command
    Recruiting - verified October 2009

  • Study of Bone Marrow and Blood Samples in Patients With Untreated Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia Enrolled on Clinical Trial CALGB-9621 or CALGB-9720

    Condition:   Leukemia
    Intervention:   Other: laboratory biomarker analysis
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • The Effects of Omalizumab (Anti-IgE) on the Late-phase Response to Nasal Allergen Challenge

    Condition:   Cat Allergy
    Interventions:   Drug: Omalizumab;   Drug: Placebo
    Sponsors:   Johns Hopkins University;   National Institute of Allergy and Infectious Diseases (NIAID);   Genentech
    Recruiting - verified October 2009

  • Confirmatory Study of 17P Versus Vehicle for the Prevention of Preterm Birth in Women With a Previous Singleton Spontaneous Preterm Delivery

    Condition:   Preterm Birth
    Interventions:   Drug: Hydroxyprogesterone Caproate Injection, 250mg/mL;   Drug: Vehicle
    Sponsors:   Hologic, Inc.;   PRA International
    Recruiting - verified October 2009

  • Extension Study of EC145 for Subjects Enrolled in a Previous Study With EC145

    Condition:   Adenocarcinoma of the Lung
    Intervention:   Drug: EC145
    Sponsor:   Endocyte
    Not yet recruiting - verified October 2009

  • Ranibizumab DosE Comparison and the Role of LAser in REtinal Vein Occlusions

    Condition:   Retinal Vein Occlusion
    Interventions:   Drug: Ranibizumab .5mg;   Drug: Ranibizumab .5mg with laser;   Drug: Ranibizumab 2.0 mg;   Drug: Ranibizumab 2.o dose with laser
    Sponsors:   Johns Hopkins University;   Genentech
    Not yet recruiting - verified October 2009

  • Acute Graft-versus-Host Disease Treatment (BMT CTN 0802)

    Conditions:   Graft-Versus-Host Disease;   Immune System Disorders
    Interventions:   Drug: Mycophenolate Mofetil;   Drug: Placebo
    Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Cancer Institute (NCI);   Blood and Marrow Transplant Clinical Trials Newtwork (BMT CTN)
    Not yet recruiting - verified October 2009

  • Clinical Trial of the PfSPZ Vaccine

    Condition:   Plasmodium Falciparum
    Intervention:   Biological: Plasmodium falciparum Sporozoite (strain NF-54; Anopheles stephensi mosquitoes) Vaccine, Live, Inactivated (gamma irradiation)
    Sponsors:   Sanaria Inc.;   The PATH Malaria Vaccine Initiative (PATH MVI)
    Recruiting - verified October 2009

  • Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma

    Conditions:   Lymphoma;   Lymphoproliferative Disorder
    Interventions:   Other: biologic sample preservation procedure;   Other: informational intervention
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • A Study of Duloxetine in Major Depressive Disorder (MDD) and Associated Painful Symptoms

    Condition:   Major Depressive Disorder
    Interventions:   Drug: Duloxetine;   Drug: Placebo
    Sponsor:   Eli Lilly and Company
    Not yet recruiting - verified November 2009

  • Safety and Efficacy of Direct Blood Volume Measurement in the Treatment of Heart Failure

    Condition:   Heart Failure
    Interventions:   Other: Daxor Blood Volume Analysis;   Other: Clinical volume status assessment
    Sponsors:   New York University School of Medicine;   Daxor Corporation
    Not yet recruiting - verified October 2009

  • A Study of RAD001 in Combination With Cetuximab and Cisplatin in Recurrent and Metastatic Squamous Cell Cancer of the Head and Neck

    Condition:   Head and Neck Cancer
    Interventions:   Drug: RAD001;   Drug: Cetuximab;   Drug: Cisplatin/Carboplatin
    Sponsors:   Sidney Kimmel Comprehensive Cancer Center;   Novartis Pharmaceuticals
    Recruiting - verified November 2009

  • Cultivating Healthy Environments in Families With Type 1 Diabetes (CHEF)

    Condition:   Type I Diabetes
    Interventions:   Behavioral: Education;   Device: CGM;   Behavioral: Problem Solving;   Behavioral: Social Learning;   Behavioral: Behavior Modification
    Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Recruiting - verified August 2009

  • Diet-Induced-Obesity Resistant Phenotypes in Humans

    Condition:   Healthy Volunteers
    Intervention:  
    Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    Recruiting - verified August 2009

  • Safety Study of Farletuzumab, Carboplatin and Pegylated Liposomal Doxorubicin (PLD) to Treat Platinum-sensitive Ovarian Cancer

    Condition:   Epithelial Ovarian Cancer
    Intervention:   Drug: Farletuzumab, Carboplatin, and Pegylated Liposomal Doxorubicin
    Sponsor:   Morphotek
    Not yet recruiting - verified October 2009

  • EPOCH Chemotherapy and Bortezomib for Associated T-Cell Leukemia Lymphoma

    Condition:   Leukemia-Lymphoma, Adult T-Cell
    Intervention:   Drug: Etoposide, Vincristine, Doxorubicin, Prednisone, Cyclophosphamide (EPOCH) with Bortezomib and Raltegravir
    Sponsor:   Washington University School of Medicine
    Not yet recruiting - verified October 2009

  • Immunogenicity of Novel H1N1 Vaccination Among HIV-Infected Compared to HIV-Uninfected Persons

    Conditions:   Influenza;   H1N1;   HIV;   Vaccine;   HIV Infections
    Intervention:  
    Sponsors:   Uniformed Services University of the Health Sciences;   Infectious Disease Clinical Research Program;   National Institute of Allergy and Infectious Diseases (NIAID)
    Not yet recruiting - verified October 2009

  • Study of Bone Marrow and Blood Samples From Patients With Leukemia or Other Hematopoietic Cancers

    Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
    Interventions:   Genetic: cytogenetic analysis;   Genetic: fluorescence in situ hybridization
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI);   Eastern Cooperative Oncology Group
    Recruiting - verified November 2009

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