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Paid Clinical Trials in Hawaii

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  • Safety and Efficacy of Direct Blood Volume Measurement in the Treatment of Heart Failure

    Condition:   Heart Failure
    Interventions:   Other: Daxor Blood Volume Analysis;   Other: Clinical volume status assessment
    Sponsors:   New York University School of Medicine;   Daxor Corporation
    Not yet recruiting - verified October 2009

  • Study of Bone Marrow and Blood Samples From Patients With Leukemia or Other Hematopoietic Cancers

    Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
    Interventions:   Genetic: cytogenetic analysis;   Genetic: fluorescence in situ hybridization
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI);   Eastern Cooperative Oncology Group
    Recruiting - verified November 2009

  • Safety and Efficacy of Once-Daily KRP-104 in Type 2 Diabetic Patients That Cannot Control Their Diabetes on Metformin Alone

    Condition:   Type 2 Diabetes
    Interventions:   Drug: KRP-104;   Drug: Placebo
    Sponsors:   ActivX Biosciences, Inc.;   Kyorin Pharmaceutical Co.,Ltd
    Recruiting - verified October 2009

  • Safety and Tolerability of TAK-491 Plus Chlorthalidone Compared to Olmesartan Medoxomil-Hydrochlorothiazide in Subjects With Essential Hypertension

    Condition:   Essential Hypertension
    Interventions:   Drug: TAK-491 and chlorthalidone;   Drug: Olmesartan medoxomil-hydrochlorothiazide
    Sponsor:   Takeda Global Research & Development Center, Inc.
    Recruiting - verified November 2009

  • Clinical Trial for Non-responders Who Previously Participated in Eltrombopag Studies TPL 103922 or TPL 108390

    Conditions:   Hepatitis C;   Thrombocytopaenia
    Intervention:   Drug: Eltrombopag
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Maraviroc Intensification and Peripheral Blood Monocyte HIV DNA Levels

    Condition:   HIV Infections
    Intervention:   Drug: maraviroc (Selzentry)
    Sponsors:   University of Hawaii;   Pfizer Pharmaceutical
    Not yet recruiting - verified September 2009

  • Effect of Rosuvastatin on Cardiovascular Risk in HIV-Infected Individuals With Low High Density Lipoprotein (HDL) Cholesterol

    Conditions:   HIV Infections;   Cardiovascular Disease
    Intervention:   Drug: rosuvastatin
    Sponsor:   University of Hawaii
    Not yet recruiting - verified September 2009

  • Study to Evaluate the Urate-Lowering Activity and Safety of Oral BCX4208 Administered in Subjects With Gout

    Condition:   Gout
    Interventions:   Drug: placebo;   Drug: BCX4208
    Sponsor:   BioCryst Pharmaceuticals
    Recruiting - verified November 2009

  • Adaptive-design Dose Finding Study to Assess the Antiviral Efficacy and Safety of NIM811 Administered in Combination With Standard of Care (SOC) in Relapsed Hepatitis C Virus 1 (HCV-1) Infected Patients

    Condition:   Chronic Hepatitis C Genotype-1 Relapse
    Interventions:   Drug: NIM811;   Drug: Placebo BID + SOC
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified November 2009

  • A Study to Determine the Safety and Efficacy of Albiglutide Administered in Combination With Insulin Glargine

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Drug: insulin glargine + preprandial lispro insulin;   Biological: albiglutide + insulin glargine
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Study to Evaluate Safety and Efficacy of Dutogliptin in Type 2 Diabetes Mellitus Subjects With Moderate and Severe Renal Impairment

    Conditions:   Type 2 Diabetes Mellitus;   Renal Impairment
    Interventions:   Drug: dutogliptin;   Drug: dutogliptin;   Drug: placebo;   Drug: sitagliptin;   Drug: sitagliptin
    Sponsors:   Phenomix;   Forest Laboratories
    Recruiting - verified November 2009

  • A Study of the Antiviral Activity, Safety, and Tolerability of Intravenous Peramivir in Adult and Adolescent Hospitalized Subjects With Confirmed or Suspected Influenza Infection

    Conditions:   Seasonal Influenza;   Cough;   Sore Throat;   Nasal Congestion;   Myalgia;   Headache;   Feverishness;   Fatigue
    Interventions:   Drug: Peramivir;   Drug: Peramivir
    Sponsors:   BioCryst Pharmaceuticals;   Department of Health and Human Services
    Recruiting - verified November 2009

  • COntrolled MyeloFibrosis Study With ORal JAK Inhibitor Treatment: The COMFORT-I Trial

    Condition:   Myelofibrosis
    Interventions:   Drug: INCB018424;   Drug: Placebo
    Sponsor:   Incyte Corporation
    Recruiting - verified November 2009

  • Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma

    Conditions:   Chordoma;   Desmoid Tumor;   Sarcoma
    Interventions:   Genetic: reverse transcriptase-polymerase chain reaction;   Other: biologic sample preservation procedure;   Other: laboratory biomarker analysis
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Blood and Bone Marrow Samples From Patients With Hematologic Cancer

    Conditions:   Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors

    Condition:   Brain and Central Nervous System Tumors
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Samples From Patients With Lung Cancer

    Condition:   Lung Cancer
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Safety, Tolerability and Efficacy Assessment of Dynacirc CR in Parkinson Disease

    Condition:   Parkinson Disease
    Interventions:   Drug: isradipine cr;   Drug: placebo/ sugar pill
    Sponsors:   The Parkinson Study Group;   Michael J. Fox Foundation;   Northwestern University Dixon Fund
    Recruiting - verified November 2009

  • Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma

    Condition:   Neuroblastoma
    Interventions:   Genetic: loss of heterozygosity analysis;   Other: cytology specimen collection procedure;   Procedure: biopsy
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of Kidney Tumors in Young Patients

    Conditions:   Kidney Cancer;   Precancerous/Nonmalignant Condition
    Interventions:   Genetic: loss of heterozygosity analysis;   Genetic: polymerase chain reaction;   Genetic: polymorphism analysis;   Other: immunohistochemistry staining method;   Procedure: computed tomography;   Procedure: magnetic resonance imaging
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer

    Conditions:   Leukemia;   Neoplasm of Uncertain Malignant Potential;   Unspecified Childhood Solid Tumor, Protocol Specific
    Intervention:   Other: cytology specimen collection procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma

    Condition:   Sarcoma
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

    Conditions:   Leukemia;   Lymphoma
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Collecting and Storing Biological Samples From Young Patients With Hodgkin's Lymphoma

    Condition:   Lymphoma
    Intervention:   Other: biologic sample preservation procedure
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

    Condition:   Brain and Central Nervous System Tumors
    Interventions:   Biological: bevacizumab;   Drug: temozolomide;   Other: placebo
    Sponsors:   Radiation Therapy Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Abiraterone Acetate in Asymptomatic or Mildly Symptomatic Patients With Metastatic Castration-Resistant Prostate Cancer

    Condition:   Prostate Cancer
    Interventions:   Drug: abiraterone acetate plus prednisone/prednisolone;   Drug: placebo plus prednisone/prednisolone
    Sponsor:   Cougar Biotechnology, Inc.
    Recruiting - verified November 2009

  • Safety and Efficacy of RAD001 (Everolimus) Monotherapy Plus Best Supportive Care in Patients With Advanced Gastric Cancer (AGC)

    Condition:   Advanced Gastric Cancer
    Interventions:   Drug: Everolimus;   Drug: everolimus placebo
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified November 2009

  • Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid for Bone Metastases

    Conditions:   Breast Cancer;   Lung Cancer;   Metastatic Cancer;   Multiple Myeloma and Plasma Cell Neoplasm;   Prostate Cancer;   Unspecified Adult Solid Tumor, Protocol Specific
    Intervention:   Procedure: assessment of therapy complications
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Everolimus in Combination With Exemestane in the Treatment of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Who Are Refractory to Letrozole or Anastrozole

    Condition:   Breast Cancer
    Interventions:   Drug: Everolimus, Exemestane;   Drug: Placebo, Exemestane
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified November 2009

  • Acute Pain Caused by Paclitaxel in Patients With Cancer

    Conditions:   Chemotherapeutic Agent Toxicity;   Neurotoxicity;   Pain;   Unspecified Adult Solid Tumor, Protocol Specific
    Interventions:   Drug: paclitaxel;   Genetic: polymorphism analysis;   Other: laboratory biomarker analysis;   Other: questionnaire administration;   Procedure: assessment of therapy complications
    Sponsors:   North Central Cancer Treatment Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • First Line Hepato Cellular Carcinoma (HCC)

    Condition:   Hepato Cellular Carcinoma (HCC)
    Interventions:   Drug: Brivanib;   Drug: Placebo;   Drug: Sorafenib;   Drug: Placebo
    Sponsor:   Bristol-Myers Squibb
    Recruiting - verified November 2009

  • Retapamulin Versus Linezolid in the Treatment of SITL and Impetigo Due to MRSA

    Conditions:   Impetigo;   Secondarily-infected Traumatic Lesions
    Interventions:   Drug: Linezolid;   Drug: Retpamulin Ointment, 1%
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Safety and Efficacy Study of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin

    Condition:   Type 2 Diabetes Mellitus
    Interventions:   Drug: dutogliptin;   Drug: placebo
    Sponsors:   Phenomix;   Forest Laboratories
    Recruiting - verified November 2009

  • A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes.

    Condition:   Type 2 Diabetes Mellitus
    Interventions:   Drug: metformin + glimepiride + pioglitazone placebo + albiglutide placebo;   Drug: metformin + glimepiride + pioglitazone + albiglutide placebo;   Biological: metformin + glimepiride + pioglitazone placebo + albiglutide
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes

    Condition:   Type 2 Diabetes Mellitus
    Interventions:   Drug: glimepiride;   Drug: metformin;   Drug: sitagliptin;   Biological: albiglutide
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009

  • Global Investigation of Therapeutic Decisions in Hepatocellular Carcinoma and of Its Treatment With Sorafenib

    Condition:   Carcinoma, Hepatocellular
    Intervention:   Drug: Sorafenib (Nexavar, BAY43-9006)
    Sponsor:   Bayer
    Recruiting - verified November 2009

  • Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or Hip

    Conditions:   Osteoarthritis;   Arthritis
    Interventions:   Drug: NSAID;   Biological: tanezumab;   Biological: tanezumab;   Biological: tanezumab;   Drug: NSAID;   Biological: tanezumab;   Drug: NSAID
    Sponsor:   Pfizer
    Recruiting - verified November 2009

  • Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer

    Conditions:   Endometrial Cancer;   Fatigue;   Neurotoxicity
    Interventions:   Drug: carboplatin;   Drug: paclitaxel;   Radiation: brachytherapy;   Radiation: intensity-modulated radiation therapy;   Radiation: radiation therapy
    Sponsors:   Gynecologic Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study of NNZ-2566 in Patients With Traumatic Brain Injury

    Condition:   Brain Injuries
    Intervention:   Drug: NNZ-2566
    Sponsor:   Neuren Pharmaceuticals Limited
    Not yet recruiting - verified November 2009

  • Global Study to Assess the Safety and Effectiveness of DU-176b vs Standard Practice of Dosing With Warfarin in Patients With Atrial Fibrillation

    Conditions:   Stroke;   Atrial Fibrillation;   Embolism
    Interventions:   Drug: warfarin tablets;   Drug: DU-176b tablets (high dose regimen);   Drug: DU-176b tablets (low dose regimen)
    Sponsors:   Daiichi Sankyo Inc.;   The TIMI Study Group
    Recruiting - verified November 2009

  • Study Evaluating Neratinib vs Lapatinib Plus Capecitabine for ErbB2 Positive Advanced Breast Cancer

    Conditions:   Advanced Breast Cancer;   Breast Cancer
    Interventions:   Drug: Neratinib;   Drug: Lapatinib plus Capecitabine
    Sponsor:   Wyeth
    Recruiting - verified October 2009

  • Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, Stage II, or Stage IIIA Breast Cancer Undergoing Chemotherapy

    Conditions:   Breast Cancer;   Chemotherapeutic Agent Toxicity;   Fatigue;   Neurotoxicity
    Interventions:   Dietary Supplement: acetyl-L-carnitine hydrochloride;   Other: placebo
    Sponsors:   Southwest Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy

    Condition:   Breast Cancer
    Interventions:   Biological: trastuzumab;   Radiation: radiation therapy
    Sponsors:   National Surgical Adjuvant Breast and Bowel Project (NSABP);   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Study To Assess The Safety, Pharmacokinetics, And Evaluate The Response To Anidulafungin When Treating Children With Invasive Candidiasis.

    Conditions:   Candidemia;   Candidiasis
    Interventions:   Drug: anidulafungin;   Drug: fluconazole
    Sponsor:   Pfizer
    Recruiting - verified November 2009

  • Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma

    Condition:   Sarcoma
    Interventions:   Drug: cisplatin;   Drug: dexrazoxane hydrochloride;   Drug: doxorubicin hydrochloride;   Drug: etoposide;   Drug: ifosfamide;   Drug: leucovorin calcium;   Drug: methotrexate;   Drug: zoledronic acid;   Procedure: adjuvant therapy;   Procedure: neoadjuvant therapy;   Procedure: therapeutic conventional surgery
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Follow-Up Study for Exubera

    Condition:   Diabetes Mellitus
    Interventions:   Drug: Exubera;   Other: Randomized diabetes therapy
    Sponsor:   Pfizer
    Recruiting - verified November 2009

  • A Phase 1 Dose Escalation Study of PF-04523655 (REDD14NP) In Subjects With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (Wet AMD)

    Condition:   Age-Related Macular Degeneration
    Intervention:   Drug: PF-04523655
    Sponsors:   Pfizer;   Quark Pharmaceuticals, Inc
    Recruiting - verified October 2009

  • Platinum Resistant Ovarian Cancer Evaluation of Doxil and EC145 Combination Therapy

    Condition:   Ovarian Cancer
    Interventions:   Drug: EC145;   Drug: pegylated liposomal doxorubicin (PLD);   Drug: EC20;   Drug: EC20
    Sponsor:   Endocyte
    Recruiting - verified October 2009

  • American Ginseng in Treating Patients With Fatigue Caused by Cancer

    Conditions:   Chronic Myeloproliferative Disorders;   Fatigue;   Leukemia;   Lymphoma;   Lymphoproliferative Disorder;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases;   Precancerous/Nonmalignant Condition;   Unspecified Adult Solid Tumor, Protocol Specific
    Interventions:   Dietary Supplement: American ginseng;   Other: placebo
    Sponsors:   North Central Cancer Treatment Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

  • Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, or Osteosarcoma

    Conditions:   Brain and Central Nervous System Tumors;   Childhood Germ Cell Tumor;   Extragonadal Germ Cell Tumor;   Liver Cancer;   Neuroblastoma;   Ototoxicity;   Ovarian Cancer;   Sarcoma
    Interventions:   Drug: sodium thiosulfate;   Procedure: observation
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Recruiting - verified November 2009

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