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Paid Clinical Trials - : Healthy Participants

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  • Healthy Volunteers
    Lotus Clinical Research is conducting a clinical research study of an investigational medication. You must be between 18 to 55 years old to participate.
  • Open-label Safety and Tolerability Study of CoVaccine HT™ in Healthy Volunteers

    Condition:   Vaccine
    Intervention:   Biological: CoVaccine HT
    Sponsor:   Protherics
    Not yet recruiting - verified November 2009
  • BIIB014 Effects on the Pharmacokinetics (PK) of Rosiglitazone, Warfarin, and Midazolam

    Condition:   Healthy
    Interventions:   Drug: BIIB014;   Drug: Placebo
    Sponsor:   Biogen Idec
    Recruiting - verified November 2009
  • A Study of the Effects of Increasing Doses of a Drug for the Treatment of Nail Fungus

    Condition:   Onychomycosis
    Interventions:   Drug: Albaconozole;   Drug: Placebo;   Drug: Albaconozole;   Drug: Placebo;   Drug: Albaconozole;   Drug: Placebo
    Sponsor:   Stiefel, a GSK Company
    Recruiting - verified November 2009
  • Vyvanse and Glucose Intolerance in Children With Attention Deficit Hyperactivity Disorder (ADHD) and Obesity

    Conditions:   Attention Deficit Hyperactivity Disorder;   Glucose Intolerance;   Obesity
    Intervention:   Drug: Lis-dexamphetamine
    Sponsors:   Duke University;   Shire Pharmaceutical Development
    Not yet recruiting - verified November 2009
  • OTIS Autoimmune Diseases in Pregnancy Project

    Conditions:   Ankylosing Spondylitis;   Psoriatic Arthritis;   Psoriasis;   Rheumatoid Arthritis
    Intervention:  
    Sponsors:   University of California, San Diego;   Organization of Teratology Information Specialists (OTIS);   Amgen
    Recruiting - verified November 2009
  • Clinical Phenotyping Resource and Biobank Core of the Michigan O'Brien Renal Center

    Conditions:   Chronic Kidney Disease;   Glomerulopathy
    Intervention:  
    Sponsors:   University of Michigan;   St. John's Health System;   University of Illinois;   Wayne State University
    Recruiting - verified November 2009
  • Treatment of Androgenetic Alopecia in Females, 12 Beam

    Conditions:   Androgenetic Alopecia;   Hair Loss;   Female Pattern Baldness
    Interventions:   Device: HairMax LaserComb 2009 model 12 beam;   Device: Sham Device
    Sponsor:   Lexington International, LLC
    Not yet recruiting - verified November 2009
  • Compliance Of Medication After Discharge From the Hospital in the Elderly

    Conditions:   Compliance of Medications;   Factors That May Affect Compliance
    Intervention:  
    Sponsor:   William Beaumont Hospitals
    Recruiting - verified November 2009
  • Single Ascending Dose Safety, Tolerability and Pharmacokinetics Study of GLYX-13 in Normal Volunteers

    Condition:   Healthy
    Interventions:   Drug: GLYX-13;   Drug: IV normal saline
    Sponsor:   Naurex, Inc
    Recruiting - verified November 2009
  • Does Auricular Acupuncture Improve Tolerance to Electromyography (EMG) Testing?

    Condition:   Pain
    Intervention:   Other: auricular acupuncture
    Sponsor:   Kessler Foundation
    Recruiting - verified November 2009
  • Reinforcing Therapist Performance

    Condition:   Implementation of Evidence-based Treatment
    Intervention:   Behavioral: Incentive Condition
    Sponsors:   Chestnut Health Systems;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting - verified November 2009
  • Clinical Evaluation of a Silicone Hydrogel Lens

    Condition:   Lotrafilcon A Contact Lens Use
    Intervention:  
    Sponsor:   Novartis
    Recruiting - verified November 2009
  • Ranibizumab Therapy for Choroidal Neovascularization (CNV) Asociated With Angioid Streaks

    Condition:   Angioid Streaks
    Intervention:   Drug: ranibizumab
    Sponsors:   University of Illinois;   Genentech
    Not yet recruiting - verified November 2009
  • Study Comparing Esomeprazole and ASA Combined Together as One Capsule Versus These Medications Taken Separately

    Condition:   Peptic Ulcer Disease
    Interventions:   Drug: Esomeprazole/ASA Fixed Combination;   Drug: Esomeprazole;   Drug: ASA
    Sponsor:   AstraZeneca
    Not yet recruiting - verified November 2009
  • Genetic Screening for Filaggrin Mutation in Atopic Dermatitis and Ichthyosis Vulgaris in the African American Population

    Conditions:   Atopic Dermatitis;   Ichthyosis Vulgaris
    Intervention:  
    Sponsors:   Northwestern University;   IBT laboratories
    Not yet recruiting - verified November 2009
  • Influence of Moxifloxacin on QTc Interval in Healthy Subjects for Positive Control Validation

    Conditions:   QTc Evaluation;   Electrocardiography
    Interventions:   Drug: Avelox (Moxifloxacin, BAY12-8039);   Drug: Placebo
    Sponsor:   Bayer
    Not yet recruiting - verified November 2009
  • Study to Evaluate the Safety and Immunogenicity of Poly ICLC (Hiltonol) in Healthy Volunteers

    Condition:   Healthy Volunteers
    Intervention:   Drug: Hiltonol (poly ICLC)
    Sponsor:   Rockefeller University
    Recruiting - verified November 2009
  • A Clinical Trial of Dermacorder for Detecting Malignant Skin Lesions

    Condition:   Basal Cell Carcinoma
    Intervention:  
    Sponsor:   Children's Hospital & Research Center Oakland
    Recruiting - verified November 2009
  • Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear

    Condition:   Corneal Staining
    Interventions:   Device: ReNu Multiplus multipurpose disinfecting solution;   Device: Control
    Sponsor:   Southern California College of Optometry
    Recruiting - verified November 2009
  • Tear Film Thickness Measured Using a Novel Technique

    Condition:   Dry Eye
    Intervention:  
    Sponsor:   Southern California College of Optometry
    Recruiting - verified November 2009
  • Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence

    Conditions:   Alcohol Dependence;   Insomnia
    Interventions:   Drug: Gabapentin or placebo dispensed to subject.;   Drug: Gabapentin or placebo dispensed to subject.
    Sponsors:   University of Michigan;   National Institutes of Health (NIH);   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting - verified November 2009
  • Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients

    Condition:   Cachexia
    Intervention:  
    Sponsor:   The University of Texas, Galveston
    Recruiting - verified November 2009
  • Ascending Dose Study of the Safety and Tolerability of REGN668 in Normal Healthy Volunteers

    Condition:   Healthy
    Intervention:   Biological: REGN668
    Sponsors:   Regeneron Pharmaceuticals;   Sanofi-Aventis
    Recruiting - verified November 2009
  • First In Human Study To Evaluate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of PF-04427429 Administered Intravenously And Subcutaneously To Healthy Adult Volunteers

    Condition:   Healthy Volunteers
    Interventions:   Drug: PF-04427429;   Drug: PF-04427429;   Drug: PF-04427429;   Drug: PF-04427429;   Drug: PF-04427429;   Drug: PF-04427429;   Drug: PF-04427429;   Drug: PF-04427429;   Drug: PF-04427429;   Drug: PF-04427429;   Drug: PF-04427429;   Drug: PF-04427429
    Sponsor:   Pfizer
    Not yet recruiting - verified November 2009
  • Dynamic Magnetic Resonance Imaging (MRI) for Lung Tumor Motion and Lung Function

    Condition:   Lung Cancer
    Intervention:  
    Sponsors:   University of Maryland;   National Institutes of Health (NIH)
    Not yet recruiting - verified November 2009
  • An Escalating Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of LNK 754 in Elderly Volunteers and in Subjects With Mild Alzheimer's Disease

    Condition:   Mild Alzheimer's Disease
    Interventions:   Drug: LNK-754;   Drug: Placebo
    Sponsor:   Link Medicine Corporation
    Recruiting - verified November 2009
  • The Effect of Weight on Vitamin D Dose Response

    Conditions:   Obesity;   Vitamin D Deficiency
    Intervention:   Dietary Supplement: cholecalciferol
    Sponsor:   Creighton University
    Recruiting - verified November 2009
  • A Trial to Evaluate the Safety and Immunogenicity of a Trivalent Seasonal Influenza Virus-Like Particle (VLP) Vaccine (Recombinant) in Older Adults

    Condition:   Influenza
    Interventions:   Biological: Investigational Influenza VLP Vaccine 15ug/strain;   Biological: Investigational Influenza VLP Vaccine 60ug/strain;   Biological: TIV
    Sponsor:   Novavax
    Recruiting - verified November 2009
  • Electronic Brachytherapy for the Treatment of NMSC

    Conditions:   Basal Cell Carcinoma;   Squamous Cell Carcinoma
    Intervention:   Radiation: electronic brachytherapy
    Sponsor:   Xoft, Inc.
    Recruiting - verified November 2009
  • The Effect of Exercise and Alagebrium on the Diastolic Function of the Heart

    Condition:   Ventricular Function
    Interventions:   Behavioral: Aerobic Exercise Training;   Drug: Alagebrium (generic: ALT-711);   Behavioral: Tai Chi and/or Yoga Training
    Sponsor:   University of Texas Southwestern Medical Center
    Recruiting - verified November 2009
  • A Spanish-Language Intervention to Enhance Routine HIV Patient Care Delivery [CARE+ Spanish]

    Condition:   HIV Infections
    Interventions:   Other: CARE+ Spanish computer counseling session;   Other: CARE+ Spanish brief computer risk assessment session
    Sponsors:   New York University;   St. Vincent's Medical Center
    Not yet recruiting - verified November 2009
  • Nephrogenic Systemic Fibrosis (NSF): A Chart Review With Analysis of Tissue Gadolinium Levels

    Conditions:   Nephrogenic Systemic Fibrosis;   Nephrogenic Fibrosing Dermopathy
    Intervention:  
    Sponsors:   Northwestern University;   National Institutes of Health (NIH)
    Recruiting - verified November 2009
  • Study of the Impact of Parental Note Taking on the Effectiveness of Anticipatory Guidance

    Conditions:   Health Education;   Sudden Infant Death
    Intervention:   Behavioral: Note taking
    Sponsors:   Boston Medical Center;   The Joel and Barbara Alpert Endowment For The Children of The City
    Not yet recruiting - verified November 2009
  • Intraoperative Bleeding During Endoscopic Sinus Surgery

    Condition:   Blood Loss
    Interventions:   Drug: propofol;   Drug: sevoflurane
    Sponsor:   University of Chicago
    Not yet recruiting - verified November 2009
  • Class 3 Biowaivers

    Condition:   Healthy
    Intervention:   Drug: cimetidine (or acyclovir)
    Sponsors:   University of Maryland;   Food and Drug Administration (FDA)
    Recruiting - verified November 2009
  • Staphylococcus Aureus Toxoids Phase 1-2 Vaccine Trial

    Condition:   Staphylococcus Aureus
    Interventions:   Biological: Monovalent rAT;   Biological: Monovalent rLukS-PV;   Biological: Bivalent rLukS-PV / rAT;   Biological: Placebo with adjuvant;   Biological: Placebo
    Sponsors:   Uniformed Services University of the Health Sciences;   Nabi Biopharmaceuticals
    Recruiting - verified November 2009
  • Methods to Augment the Efficacy of Aspirin and Clopidogrel in Healthy Subjects and Patients With Stable Coronary Artery Disease With an Elevated Platelet Turnover (Reticulated Platelets)

    Condition:   Coronary Artery Disease
    Interventions:   Drug: Asprin;   Drug: Clopidogrel
    Sponsor:   The Methodist Hospital System
    Recruiting - verified November 2009
  • Depression Management at the Workplace

    Condition:   Depression
    Interventions:   Other: Depression Product Detailing;   Other: Depression HEDIS detailing
    Sponsors:   Florida State University;   Colorado Business Group on Health
    Recruiting - verified November 2009
  • The Physical Effects of Pain Catastrophizing in Labor

    Condition:   Pregnancy
    Intervention:  
    Sponsor:   Oregon Health and Science University
    Recruiting - verified November 2009
  • The Effect of a New Emulsion in Dry Eye Patients on Tear Layer Aberrometry, Contrast Sensitivity, and Reading Ability

    Condition:   Dry Eye Syndrome
    Interventions:   Drug: Optive;   Drug: Soothe;   Drug: New Emulsion
    Sponsors:   Southern California College of Optometry;   Allergan
    Recruiting - verified November 2009
  • Studying Genes, Environment, and Prostate Cancer Risk in Patients With or Without Prostate Cancer and Their First-Degree Relatives

    Condition:   Prostate Cancer
    Interventions:   Genetic: DNA analysis;   Genetic: polymorphism analysis;   Other: laboratory biomarker analysis;   Other: medical chart review;   Other: questionnaire administration;   Procedure: evaluation of cancer risk factors;   Procedure: study of high risk factors
    Sponsor:   Veterans Affairs Medical Center - Portland
    Recruiting - verified November 2009
  • Physician Perceptions About Parenteral Hydration in Latin America and Spain

    Conditions:   Dehydration;   Advanced Cancers
    Intervention:   Behavioral: Survey
    Sponsor:   M.D. Anderson Cancer Center
    Not yet recruiting - verified November 2009
  • Internal Monitoring of Eye Movement in Schizophrenia

    Condition:   Schizophrenia
    Intervention:  
    Sponsor:   National Eye Institute (NEI)
    Recruiting - verified October 2009
  • The Biology of Resilience

    Condition:   Stress Response
    Interventions:   Drug: intranasal oxytocin;   Drug: Placebo;   Behavioral: Social support;   Behavioral: No Social Support;   Other: Female gender;   Other: Male Gender
    Sponsors:   Harvard School of Public Health;   Brigham and Women's Hospital
    Recruiting - verified November 2009
  • The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise

    Conditions:   Herpesvirus;   Adenovirus;   Cytomegalovirus;   Human Papillomavirus;   Human Polyomavirus;   Respiratory Viruses
    Intervention:  
    Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
    Recruiting - verified October 2009
  • Impact of Lucentis on Psychological Morbidity in Patients With Retinal Vein Occlusion

    Conditions:   Branch Retinal Vein Occlusion;   Central Retinal Vein Occlusion;   Retinal Vein Occlusion;   Depression
    Intervention:   Drug: ranibizumab (Lucentis)
    Sponsors:   Retina Associates of Cleveland, Inc;   Genentech
    Recruiting - verified November 2009
  • In-vivo Wettability Grading and Assessment Study

    Condition:   Myopia
    Interventions:   Device: lotrafilcon B;   Device: Balafilcon A;   Device: Senofilcon A;   Device: enfilcon A
    Sponsor:   Novartis
    Recruiting - verified November 2009
  • Comparison of Three Methods of Taking Temperatures in the Newborn Intensive Care Unit

    Condition:   Thermometry
    Intervention:  
    Sponsor:   Christiana Care Health Services
    Not yet recruiting - verified November 2009
  • South Florida Residents Knowledge and Opinions on End-of-Life Issues

    Condition:   Healthy
    Intervention:  
    Sponsor:   Nova Southeastern University
    Recruiting - verified September 2009
  • The Expression of PTEN Protein and mRNA in Malignant Cells of Chronic Myelomonocytic Leukemia

    Condition:   Chronic Myelomonocytic Leukemia
    Intervention:  
    Sponsor:   University of Arkansas
    Recruiting - verified November 2009
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