Paid Clinical Trials and Focus Groups by Category |
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Condition: Cardiovascular Disease
Interventions: Drug: Active Clonidine; Drug: Placebo Clonidine; Drug: Active ASA; Drug: Placebo ASA
Sponsor: Hamilton Health Sciences
Not yet recruiting - verified March 2010
Conditions: Chronic Kidney Disease; Hypertriglyceridemia
Interventions: Dietary Supplement: n-3 Fatty Acid supplement; Dietary Supplement: Placebo
Sponsor: The Hospital for Sick Children
Active, not recruiting - verified March 2010
Condition: Glaucoma
Interventions: Procedure: Argon laser trabeculoplasty; Procedure: Selective laser trabeculoplasty
Sponsor: Sunnybrook Health Sciences Centre
Completed - verified March 2010
Conditions: Sepsis; Shock
Intervention:
Sponsor: London Health Sciences Centre
Recruiting - verified December 2009
Condition: Endothelial Function
Interventions: Dietary Supplement: Cinnamon; Dietary Supplement: Oregano; Dietary Supplement: Ginger; Dietary Supplement: Rosemary; Dietary Supplement: Black pepper; Dietary Supplement: Placebo
Sponsors: Laval University; McCormick Canada Co
Recruiting - verified March 2010
Condition: Primary Sclerosing Cholangitis
Intervention: Drug: ursodeoxycholic acid (UDCA) withdrawal and reinstitution
Sponsors: University of Tennessee; Mount Sinai School of Medicine; Children's Memorial Hospital; University of California, San Francisco; The Hospital for Sick Children; University of Colorado, Denver; Children's Hospital Medical Center, Cincinnati; University of Pittsburgh
Not yet recruiting - verified March 2010
Condition: Extubation
Intervention:
Sponsors: Ottawa Hospital Research Institute; The Physicians' Services Incorporated Foundation
Completed - verified March 2010
Condition: Non-idiopathic Scoliosis
Interventions: Drug: Tranexamic acid 10mg/kg/hr; Drug: Tranexamic acid 100 mg/kg/h infusion; Drug: Saline solution
Sponsor: The Hospital for Sick Children
Recruiting - verified March 2010
Condition: Breast Density ≥ 50%
Intervention: Procedure: tomosynthesis
Sponsors: Alberta Health Services; Hologic, Inc.
Not yet recruiting - verified March 2010
Conditions: Myocardial Infarction; Left Ventricular Systolic Dysfunction; Anterior Akinesis; Apical Akinesis
Intervention:
Sponsor: Universitaire de Sherbrooke
Not yet recruiting - verified March 2010
Conditions: Mild Cognitive Impairment; Alzheimer's Disease
Intervention:
Sponsors: Alzheimer's Disease Cooperative Study (ADCS); National Institute on Aging (NIA); National Institutes of Health (NIH)
Not yet recruiting - verified March 2010
Condition: Stroke
Interventions: Other: Mission Possible; Other: delayed mission possible
Sponsors: McGill University; Canadian Stroke Network
Recruiting - verified September 2009
Condition: Post-tetanic Count on One Arm, the Other Arm is the Control
Intervention: Device: NMT (a device that can do neurostimulation and can record the response on the stimulation by Datex)
Sponsor: Maisonneuve-Rosemont Hospital
Recruiting - verified March 2010
Condition: Pregnant Women With Peripartum Cardiomyopathy
Intervention:
Sponsors: University of Pittsburgh; National Institutes of Health (NIH)
Recruiting - verified March 2010
Condition: Vulvovaginal Atrophy
Intervention:
Sponsors: Lawson Health Research Institute; Kimberly-Clark Corporation
Recruiting - verified March 2010
Condition: Coronary Artery Disease
Interventions: Drug: Bivalirudin; Drug: Heparin
Sponsor: Laval University
Active, not recruiting - verified October 2009
Condition: Pulmonary Arterial Hypertension (Idiopathic, Familial or Anorexigen-associated)
Interventions: Drug: Dichloroacetate Sodium; Drug: Dichloroacetate Sodium; Drug: Dichloroacetate Sodium
Sponsors: University of Alberta; Imperial College London
Enrolling by invitation - verified March 2010
Conditions: Cardiac Surgery; Pain; Adult; Pain Management
Intervention: Behavioral: soulageTAVIE
Sponsors: Centre hospitalier de l'Université de Montréal (CHUM); Canadian Institutes of Health Research (CIHR); GRISIIQ; FIIC; Chaire de recherche sur les nouvelles pratiques de soins infirmiers
Recruiting - verified February 2010
Conditions: Bipolar Disorder; Cyclothymia; Borderline Personality Disorder
Intervention: Other: Mental health telemetry (MHT)
Sponsors: Sunnybrook Health Sciences Centre; Motorola Canada
Not yet recruiting - verified March 2010
Condition: Acute Asthma
Interventions: Behavioral: Opinion Leader; Behavioral: Usual care
Sponsor: University of Alberta
Not yet recruiting - verified February 2010
Condition: Otitis Media With Effusion
Interventions: Drug: Lansoprazole; Drug: Placebo
Sponsors: Hamilton Health Sciences; McMaster University
Not yet recruiting - verified March 2010
Conditions: Parkinson's Disease; Depression
Intervention: Device: Transcranial Magnetic Stimulator
Sponsors: Beth Israel Deaconess Medical Center; Michael J. Fox Foundation for Parkinson's Research
Not yet recruiting - verified March 2010
Condition: Advanced Cancer
Intervention: Behavioral: Living with Hope Program
Sponsor: University of Saskatchewan
Recruiting - verified March 2010
Conditions: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee
Interventions: Other: in-person; Other: web-based
Sponsors: University of Western Ontario, Canada; The Physicians' Services Incorporated Foundation
Recruiting - verified March 2010
Conditions: Ovarian Cancer; Bowel Obstruction
Interventions: Drug: Cisplatin; Drug: Paclitaxel
Sponsor: University Health Network, Toronto
Recruiting - verified February 2010
Condition: Severe Hemophilia A
Interventions: Biological: Recombinant Factor VIII (Advate/Helixate FS/KoegenateFS); Biological: Recombinant Factor VIII (Advate/Helixate FS/KoegenateFS)
Sponsor: The Hospital for Sick Children
Active, not recruiting - verified March 2010
Conditions: Infection; Osteoarthritis of the Knee
Interventions: Device: Simplex™ P with Tobramycin; Device: Simplex™ P
Sponsor: University of Western Ontario, Canada
Not yet recruiting - verified March 2010
Condition: Knee Osteoarthritis
Interventions: Dietary Supplement: Glucosamine sulphate; Other: Placebo
Sponsor: University of British Columbia
Not yet recruiting - verified February 2010
Conditions: Pulmonary Disease, Chronic Obstructive; Bronchitis, Chronic; Emphysema
Intervention: Other: Eccentric exercise training
Sponsors: McGill University; McGill University Health Center
Recruiting - verified December 2009
Condition: Thyroid Cancer
Intervention: Other: Decision aid exposure
Sponsors: University Health Network, Toronto; Ontario Ministry of Health and Long Term Care; Canadian Institutes of Health Research (CIHR)
Recruiting - verified January 2010
Conditions: Schizophrenia; Schizoaffective Disorder
Intervention: Behavioral: Behavioural Intervention for the Prevention of Weight Gain
Sponsors: Centre for Addiction and Mental Health; Canadian Institutes of Health Research (CIHR)
Recruiting - verified March 2010
Conditions: Migraine; Headache; Pediatric
Intervention: Drug: Normal saline
Sponsor: University of Alberta
Not yet recruiting - verified February 2010
Condition: Radiculopathy
Intervention: Drug: Kenalog and Sensorcaine
Sponsor: Saint John Regional Hospital
Not yet recruiting - verified January 2010
Conditions: Multiple Sclerosis; Optic Neuritis; Minocycline
Intervention: Drug: Minocycline
Sponsors: University of Calgary; Neuroscience Canada
Recruiting - verified February 2010
Condition: Hemorrhage
Interventions: Drug: Indomethacin; Drug: Acetaminophen & Indomethacin; Drug: Acetaminophen
Sponsor: Queen's University
Completed - verified February 2010
Condition: Cardiac Surgery
Interventions: Procedure: Remote Ischemic Preconditioning; Procedure: Sham
Sponsors: Hamilton Health Sciences; Canadian Network and Centre for Trials Internationally
Not yet recruiting - verified January 2010
Condition: Pregnancy
Intervention:
Sponsor: Universitaire de Sherbrooke
Recruiting - verified February 2010
Condition: Parkinson's Disease
Interventions: Drug: Amantadine; Drug: Placebo
Sponsors: Rush University Medical Center; Michael J. Fox Foundation for Parkinson's Research
Recruiting - verified February 2010
Condition: Thrombosis
Interventions: Drug: Variation of heparin dose; Drug: Variation of heparin dose
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
Not yet recruiting - verified February 2010
Condition: Pain
Interventions: Drug: Morphine; Drug: Morphine; Drug: Morphine
Sponsor: University of British Columbia
Not yet recruiting - verified February 2010
Condition: Pruritus
Interventions: Drug: Naloxone; Drug: Saline/Morphine
Sponsor: University of British Columbia
Not yet recruiting - verified February 2010
Conditions: Wegener's Granulomatosis; Microscopic Polyangiitis; Churg Strauss Syndrome; Polyarteritis Nodosa; Giant Cell Arteritis; Takayasu Arteritis
Intervention:
Sponsors: University of Oxford; American College of Rheumatology; The European League Against Rheumatism (EULAR); The Vasculitis foundation
Not yet recruiting - verified February 2010
Condition: Labor Induction at Term
Intervention: Drug: Misoprostol
Sponsor: University of Manitoba
Not yet recruiting - verified February 2010
Condition: Asthma
Intervention: Other: Electronic Asthma Action Plan System
Sponsor: St. Michael's Hospital, Toronto
Not yet recruiting - verified February 2010
Condition: Graft Versus Host Disease
Interventions: Drug: Rituximab; Drug: Prednisone
Sponsors: University Health Network, Toronto; Hoffmann-La Roche
Not yet recruiting - verified February 2010
Condition: Apnea of Prematurity
Interventions: Other: CO2 inhalation; Drug: Theophylline
Sponsors: University of Manitoba; Canadian Institutes of Health Research (CIHR); The Children's Hospital Foundation of Manitoba
Completed - verified January 2010
Condition: Cystic Fibrosis
Intervention: Dietary Supplement: Vitamin: Choline Bitartrate (2-hydroxyethyl) trimethylammonium salt 1:1
Sponsors: University of British Columbia; Cystic Fibrosis Foundation (US)
Completed - verified February 2010
Condition: Stress
Intervention: Behavioral: portable biofeedback tool and relaxation breathing technique
Sponsors: University of Calgary; Alberta Health Services; University of Calgary Department of Medicine and Faculty of Kinesiology
Completed - verified February 2010
Condition: Crisis Resource Management
Interventions: Other: Peer-led debriefing; Other: Expert instructor debriefing
Sponsor: St. Michael's Hospital, Toronto
Active, not recruiting - verified January 2010
Conditions: Asthma; Cough Variant Asthma
Interventions: Drug: high-dose methacholine challenge test; Other: mannitol challenge test
Sponsor: Queen's University
Recruiting - verified March 2010
Condition: Levels of Fatty Acids in the Blood Cells of Infants
Intervention:
Sponsors: Mead Johnson; University of Alberta
Recruiting - verified March 2010
Condition: Interstitial Lung Disease
Intervention: Other: Pulmonary rehabilitation
Sponsor: University of California, San Francisco
Recruiting - verified January 2010
Condition: Renal Cell Carcinoma
Intervention: Drug: Definity
Sponsors: University Health Network, Toronto; Lantheus Medical Imaging
Recruiting - verified February 2010
Conditions: Brain Tumor; Intracranial Pressure
Interventions: Drug: Mannitol; Drug: Mannitol
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
Not yet recruiting - verified February 2010
Condition: Cellulitis
Interventions: Drug: IV cefazolin plus oral probenecid and placebo cephalexin; Drug: Oral cephalexin and saline IV plus probenecid placebo
Sponsors: Kelowna General Hospital; Canadian Society of Hospital Pharmacists; Capital Health, Canada; Interior Health, Canada
Not yet recruiting - verified December 2009
Conditions: Cough; Anesthesia; Extubation
Interventions: Drug: Remifentanil; Drug: Remifentanil; Drug: lidocaine
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
Not yet recruiting - verified February 2010
Condition: Patients With Pacemaker With Conduction Problems
Intervention: Device: Pacing mode
Sponsors: Montreal Heart Institute; Sorin Group Canada
Active, not recruiting - verified November 2009
Conditions: Endometrial Cancer; Gastrointestinal Carcinoid Tumor; Islet Cell Tumor; Liver Cancer; Lung Cancer; Ovarian Cancer
Interventions: Biological: bevacizumab; Drug: temsirolimus; Other: laboratory biomarker analysis
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Recruiting - verified March 2010
Condition: Influenza A Virus H1N1 Subtype
Intervention: Drug: Oseltamivir
Sponsors: University of Manitoba; Hoffmann-La Roche
Recruiting - verified March 2010
Condition: Patients Undergoing Elective General Anesthesia.
Interventions: Procedure: Tracheal intubation; Procedure: Tracheal intubation
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
Recruiting - verified March 2010
Condition: Preterm Birth
Interventions: Procedure: Transvaginal ultrasound; Procedure: Vaginal secretion sampling
Sponsor: Universitaire de Sherbrooke
Completed - verified February 2010
Condition: Infant Immunizations
Intervention: Biological: Pediacel® and Infanrix™-IPV/Hib
Sponsors: Dalhousie University; IWK Health Centre; Sanofi Pasteur MSD
Recruiting - verified October 2009
Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: Bronchodilator Agents; Drug: Normal saline; Device: Dead space breathing; Device: Room air breathing
Sponsors: Queen's University; Canadian Lung Association
Not yet recruiting - verified March 2010
Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: fentanyl; Drug: normal saline (placebo)
Sponsor: Queen's University
Recruiting - verified March 2010
Condition: Macular Edema
Interventions: Drug: Ketorolac 0.5%; Other: Saline drops
Sponsor: Queen's University
Recruiting - verified March 2010
Condition: Psoriasis
Intervention: Drug: etanercept 50 mg
Sponsors: Innovaderm Research Inc.; Amgen
Recruiting - verified March 2010
Condition: Neuropathic Pain
Interventions: Drug: Pregabalin; Drug: Placebo
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
Not yet recruiting - verified February 2010
Condition: Rheumatoid Arthritis
Intervention: Drug: Rituximab
Sponsors: University of Manitoba; Hoffmann-La Roche
Recruiting - verified February 2010
Condition: Chronic Hepatitis C
Intervention: Drug: Pegylated Interferons (Peg-IFN) and Ribavirin
Sponsors: University of Manitoba; Roche Pharma AG
Recruiting - verified February 2010
Condition: Severe Asthma
Intervention:
Sponsor: University of Alberta
Not yet recruiting - verified March 2010
Conditions: Myocardial Infarction; Stroke; Renal Failure
Interventions: Drug: atorvastatin 80 mg per os daily; Drug: placebo
Sponsor: University of Alberta
Recruiting - verified February 2010
Condition: Kidney Transplant
Interventions: Biological: Zostavax (Live attenuated herpes zoster vaccine); Biological: Placebo vaccine
Sponsor: University of Alberta
Recruiting - verified February 2010
Condition: Preeclampsia
Intervention:
Sponsors: Universitaire de Sherbrooke; Fondation des étoiles
Recruiting - verified February 2010
Condition: Premature Rupture of Fetal Membranes
Intervention:
Sponsors: Universitaire de Sherbrooke; Canadian Institutes of Health Research (CIHR)
Completed - verified February 2010
Conditions: Obstetric Labor Complications; Prolonged Pregnancy
Intervention:
Sponsors: Universitaire de Sherbrooke; Fonds de la Recherche en Santé du Québec
Recruiting - verified February 2010
Condition: Rectal Cancer
Interventions: Device: prone pillow and simple ankle fixation device; Device: Customized Vacuum Immobilization Device (CVID)
Sponsor: University Health Network, Toronto
Recruiting - verified February 2010
Condition: Atrial Fibrillation
Interventions: Drug: Warfarin; Drug: Warfarin
Sponsor: University of British Columbia
Completed - verified March 2010
Condition: Breast Cancer
Intervention: Procedure: Cone Beam CT
Sponsor: University Health Network, Toronto
Recruiting - verified February 2010
Condition: Prostate Cancer
Intervention:
Sponsor: University Health Network, Toronto
Active, not recruiting - verified February 2010
Conditions: Atrial Fibrillation; Arrhythmia; Stroke Prevention; Mortality
Interventions: Device: Left atrial ablation; Drug: Rate or Rhythm Control Therapy
Sponsors: Mayo Clinic; National Heart, Lung, and Blood Institute (NHLBI); Duke University; St. Jude Medical; Biosense Webster, Inc.
Recruiting - verified February 2010
Condition: Bladder Cancer
Intervention: Other: Using Cone beam CT in patients with Bladder Cancer
Sponsor: University Health Network, Toronto
Recruiting - verified February 2010
Conditions: Breast Cancer; Invasive Breast Cancer
Intervention: Procedure: Sentinel Lymph Node Biopsy
Sponsors: Centre hospitalier de l'Université de Montréal (CHUM); Fondation du cancer du sein du Québec
Recruiting - verified May 2009
Condition: Heart Failure
Intervention: Device: Device programming
Sponsors: Montreal Heart Institute; St. Jude Medical; Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified May 2009
Condition: Heart Failure
Interventions: Device: CRT on; Device: CRT off
Sponsors: Montreal Heart Institute; St. Jude Medical; Canadian Institutes of Health Research (CIHR)
Recruiting - verified May 2009
Conditions: Arterial Occlusive Diseases; Coronary Disease; Heart Diseases; Myocardial Ischemia; Vascular Diseases; Arteriosclerosis; Ischemia; Coronary Artery Disease
Intervention: Procedure: 320 Volume Detector Computed Tomography
Sponsors: Johns Hopkins University; Toshiba America Medical Systems, Inc.
Recruiting - verified November 2009
Conditions: Mesothelioma; Pleural Mesothelioma
Interventions: Drug: Pemetrexed; Drug: Cisplatin
Sponsors: University Health Network, Toronto; Eli Lilly and Company
Recruiting - verified March 2010
Condition: Depression
Interventions: Drug: venlafaxine XR plus aripiprazole; Drug: venlafaxine plus placebo
Sponsor: University of Pittsburgh
Recruiting - verified March 2010
Conditions: Hodgkin's Lymphoma; Non Hodgkin's Lymphoma
Intervention: Biological: PET Scan
Sponsor: University Health Network, Toronto
Recruiting - verified February 2010
Conditions: Down Syndrome; Trisomy 21
Intervention:
Sponsors: Women and Infants Hospital of Rhode Island; Sequenom, Inc.
Recruiting - verified February 2010
Condition: Pregnancy
Interventions: Procedure: IUC; Procedure: IUC; Device: Levonorgestrel-releasing Intrauterine System [LNG-IUC] or FlexiT380 Copper Intrauterine Device [CuT380-IUD]; Device: Levonorgestrel-releasing Intrauterine System [LNG-IUC] or FlexiT380 Copper Intrauterine Device [CuT380-IUD]
Sponsors: University of British Columbia; Women's Health Research Institute of British Columbia; College Of Family Physicians
Recruiting - verified February 2010
Condition: Malignant Melanoma
Interventions: Drug: ABI-007; Drug: Dacarbazine
Sponsors: Abraxis BioScience Inc.; University of Arizona
Recruiting - verified August 2009
Conditions: HIV Infection; Herpesvirus 2, Human; HIV Infections
Interventions: Drug: valacyclovir; Drug: Placebo
Sponsor: University Health Network, Toronto
Recruiting - verified March 2010
Condition: Cardiovascular Disease
Interventions: Drug: active clonidine; Drug: active ASA; Drug: Clonidine Placebo; Drug: ASA Placebo
Sponsors: McMaster University; The Physicians' Services Incorporated Foundation; Canadian Network and Centre for Trials Internationally
Completed - verified March 2010
Conditions: Anxiety; Depression
Interventions: Behavioral: mindful meditation; Behavioral: interpersonal therapy
Sponsors: University of Saskatchewan; Royal University Hospital Foundation, Saskatoon, SK, Canada
Enrolling by invitation - verified March 2009
Conditions: Mucocutaneous Lymph Node Syndrome; Kawasaki Disease
Interventions: Drug: Etanercept; Drug: Placebo
Sponsors: Seattle Children's Hospital; FDA Office of Orphan Products Development; Amgen
Recruiting - verified March 2010
Condition: Acute Coronary Syndrome
Interventions: Drug: Apixaban; Drug: Placebo
Sponsors: Bristol-Myers Squibb; Pfizer; Duke University
Recruiting - verified October 2009
Condition: Schizophrenia
Interventions: Behavioral: Cognitive Behavioral Social Skills Training (CBSST) plus treatment as usual; Behavioral: Treatment as usual (TAU)
Sponsor: Centre for Addiction and Mental Health
Recruiting - verified March 2010
Condition: Healthy
Intervention: Dietary Supplement: food product
Sponsor: University of Manitoba
Completed - verified February 2010
Condition: Metastatic Colorectal Cancer
Intervention: Drug: Irinotecan, Xeloda and Oxaliplatin (IXO) Regimen with Avastin (Bevacizumab)
Sponsors: Ottawa Hospital Research Institute; Hoffmann-La Roche; Pfizer; Sanofi-Aventis; Ottawa Regional Cancer Foundation
Recruiting - verified March 2010
Conditions: Schizophrenia; Schizoaffective Disorder
Intervention: Drug: ziprazidone
Sponsors: Centre for Addiction and Mental Health; Pfizer
Recruiting - verified March 2010
Conditions: Atrial Fibrillation; Venous Thromboembolism; Ischemic Stroke; Myocardial Infarction
Interventions: Drug: warfarin; Drug: warfarin
Sponsor: Hamilton Health Sciences
Completed - verified November 2009
Condition: Cystic Fibrosis
Interventions: Drug: Ataluren (PTC124); Drug: Placebo
Sponsors: PTC Therapeutics; Genzyme; Cystic Fibrosis Foundation
Recruiting - verified March 2010
Condition: Multiple Myeloma
Intervention: Radiation: Total Marrow Irradiation
Sponsor: Ottawa Hospital Research Institute
Recruiting - verified March 2010
Condition: Malignant Pleural Mesothelioma
Intervention: Other: Pre-op RT +/- chemotherapy
Sponsor: University Health Network, Toronto
Recruiting - verified February 2010
Condition: Venous Thromboembolism
Intervention:
Sponsors: Ottawa Hospital Research Institute; Heart and Stroke Foundation of Ontario
Recruiting - verified March 2010
Conditions: HIV; Hepatitis C
Interventions: Behavioral: Motivational interviewing; Behavioral: Educational intervention
Sponsors: Universitaire de Sherbrooke; Fonds de la Recherche en Santé du Québec
Recruiting - verified February 2010
Condition: Ankle Injury
Intervention: Other: LRAR Implementation
Sponsor: The Hospital for Sick Children
Recruiting - verified March 2010
Condition: Frail Elderly
Intervention: Other: Core
Sponsor: McGill University
Completed - verified March 2010
Conditions: Lung Cancer; Precancerous Condition
Interventions: Dietary Supplement: inositol; Other: placebo
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Recruiting - verified August 2009
Condition: Gastroenteritis
Interventions: Drug: Lacidophil (experimental high dose); Drug: Lacidophil (experimental standard dose); Drug: Placebo
Sponsor: The Hospital for Sick Children
Recruiting - verified February 2010
Condition: End Stage Renal Disease
Interventions: Procedure: muscle sympathetic nerve activity measurement; Procedure: Bio impedence testing
Sponsors: Ottawa Hospital Research Institute; Heart and Stroke Foundation of Ontario; University of Ottawa
Recruiting - verified March 2010
Condition: Prostatic Neoplasms
Intervention:
Sponsors: University of Washington; Canary Foundation; Early Detection Research Network
Recruiting - verified February 2010
Condition: Diabetes Mellitus, Type 2
Interventions: Drug: LY2189265; Drug: Sitagliptin 100mg, 24 months; Drug: Placebo solution; Drug: Placebo tablet, 6 months; Drug: Placebo tablet, 24 months; Drug: Sitagliptin 100 mg, 18 months
Sponsors: Eli Lilly and Company; United BioSource Corporation; Tessella Inc.; Berry Consultants
Recruiting - verified March 2010
Condition: Colorectal Cancer
Interventions: Procedure: therapeutic conventional surgery; Procedure: therapeutic laparoscopic surgery
Sponsors: American College of Surgeons; National Cancer Institute (NCI)
Recruiting - verified March 2010
Condition: Acute Coronary Syndrome
Interventions: Drug: Clopidogrel; Drug: Prasugrel; Drug: Commercially-available Aspirin
Sponsors: Eli Lilly and Company; Daiichi Sankyo Co., Ltd.; Duke University
Recruiting - verified March 2010
Conditions: Neoplasm; Lymphoma
Intervention: Drug: ridaforolimus
Sponsors: Ariad Pharmaceuticals; H. Lee Moffitt Cancer Center and Research Institute; Pediatric Cancer Foundation; University of Colorado, Denver; All Children's Hospital; Memorial Sloan-Kettering Cancer Center
Recruiting - verified March 2010
Condition: Prostate Cancer
Interventions: Drug: vandetanib; Drug: Placebo
Sponsors: AstraZeneca; Canadian Urology Research Consortium
Terminated - verified February 2010
Conditions: Ovarian Carcinoma; Breast Cancer
Intervention: Drug: AZD2281
Sponsors: AstraZeneca; British Columbia Cancer Agency
Active, not recruiting - verified March 2010
Condition: Type 1 Diabetes Mellitus
Interventions: Biological: otelixizumab; Biological: placebo
Sponsors: Tolerx Inc.; Juvenile Diabetes Research Foundation
Active, not recruiting - verified March 2009
Condition: Post-Traumatic Stress Disorder
Intervention: Device: Repetitive Transcranial Magnetic Stimulation (rTMS) (MagPro, Medtronic)
Sponsor: Queen's University
Recruiting - verified March 2010
Conditions: Breast Cancer; Cognitive/Functional Effects; Fatigue; Psychosocial Effects of Cancer and Its Treatment; Sleep Disorders
Interventions: Procedure: assessment of therapy complications; Procedure: cognitive assessment; Procedure: fatigue assessment and management; Procedure: psychosocial assessment and care
Sponsors: International Breast Cancer Study Group; National Cancer Institute (NCI); Australian New Zealand Breast Cancer Trials Group; Cancer and Leukemia Group B
Recruiting - verified March 2010
Condition: Repetitive Transcranial Magnetic Stimulation
Interventions: Device: repetitive transcranial magnetic stimulation (rTMS); Device: repetitive transcranial magnetic stimulation (rTMS); Device: sham repetitive transcranial magnetic stimulation (rTMS)
Sponsor: Centre for Addiction and Mental Health
Active, not recruiting - verified February 2010
Condition: Chronic Obstructive Pulmonary Disease
Interventions: Behavioral: Arm training program; Behavioral: Purdue pegboard test (sham)
Sponsor: West Park Healthcare Centre
Completed - verified February 2010
Condition: Psoriasis Vulgaris
Interventions: Drug: Etanercept 50 mg; Drug: Etanercept 50 mg; Device: nbUVB
Sponsors: Innovaderm Research Inc.; Amgen
Completed - verified March 2010
Condition: Sarcoma
Intervention: Drug: RG1507
Sponsors: Hoffmann-La Roche; Sarcoma Alliance for Research through Collaboration
Active, not recruiting - verified February 2010
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: temozolomide; Genetic: DNA methylation analysis; Other: laboratory biomarker analysis; Procedure: adjuvant therapy; Procedure: quality-of-life assessment; Radiation: radiation therapy
Sponsors: European Organization for Research and Treatment of Cancer; NCIC Clinical Trials Group; Radiation Therapy Oncology Group; Medical Research Council
Recruiting - verified March 2010
Condition: Depression
Intervention:
Sponsor: Queen's University
Recruiting - verified March 2010
Condition: Major Depressive Disorder
Interventions: Device: transcranial direct current stimulation (tDCS); Device: Sham treatment
Sponsor: Centre for Addiction and Mental Health
Recruiting - verified March 2010
Condition: Postoperative Pain.
Interventions: Drug: Pregabalin; Drug: Placebo/Lactose
Sponsor: University of Manitoba
Recruiting - verified March 2010
Condition: Obsessive Compulsive Disorder
Interventions: Device: repetitive transcranial magnetic stimulation; Device: sham (placebo)
Sponsors: Queen's University; Military Medical Academy; Dokuz Eylul University
Recruiting - verified March 2010
Condition: Generalized Anxiety Disorder
Interventions: Device: Repetitive transcranial magnetic stimulation; Device: placebo sham
Sponsors: Queen's University; Military Medical Academy
Recruiting - verified March 2010
Condition: Cervical Cancer
Interventions: Procedure: Total Abdominal Radical Hysterectomy; Procedure: Total Laparoscopic or Robotic Radical Hysterectomy
Sponsors: Queensland Centre for Gynaecological Cancer; M.D. Anderson Cancer Center
Recruiting - verified February 2010
Condition: Distal Radius Fractures
Interventions: Device: Fiberglass short arm cast; Device: Prefabricated wrist splint
Sponsor: The Hospital for Sick Children
Completed - verified March 2010
Condition: Burns
Intervention:
Sponsor: The University of North Carolina, Chapel Hill
Completed - verified February 2010
Condition: Glaucoma
Interventions: Procedure: Trabeculectomy with anterior chamber infusion system; Procedure: Trabeculectomy without anterior chamber infusion system
Sponsors: Queen's University; Glaucoma Research & Education Group
Terminated - verified March 2010
Condition: Pregnant Women
Interventions: Biological: Tdap; Biological: Td
Sponsors: Dalhousie University; IWK Health Centre; Sanofi Pasteur MSD
Recruiting - verified February 2010
Condition: Colorectal Cancer
Interventions: Biological: cetuximab; Biological: pertuzumab; Genetic: fluorescence in situ hybridization; Genetic: gene expression analysis; Genetic: mutation analysis; Genetic: polymerase chain reaction; Other: immunohistochemistry staining method; Other: laboratory biomarker analysis
Sponsors: Dana-Farber Cancer Institute; National Cancer Institute (NCI)
Recruiting - verified December 2008
Condition: Whiplash Injuries
Intervention: Other: Programs of Care
Sponsors: University Health Network, Toronto; AVIVA Canada; Canadian Institutes of Health Research (CIHR)
Recruiting - verified November 2009
Condition: Cystic Fibrosis
Intervention: Drug: inhaled 7% hypertonic saline (HS)
Sponsors: CF Therapeutics Development Network Coordinating Center; Cystic Fibrosis Foundation
Completed - verified February 2010
Condition: Pneumothorax
Interventions: Procedure: chest drainage; Other: close clinical observation
Sponsors: University of Calgary; Centre Hospitalier Affilie, Universitaire de Quebec; Sunnybrook Health Sciences Centre; Canadian Intensive Care Foundation
Recruiting - verified March 2010
Conditions: Atherosclerosis; Myocardial Ischemia; Myocardial Infarction
Interventions: Drug: SCH 530348; Drug: Placebo
Sponsors: Schering-Plough; Duke University
Recruiting - verified March 2010
Condition: Lung Cancer
Interventions: Procedure: therapeutic thoracoscopy; Procedure: videothoracoscopy
Sponsors: Cancer and Leukemia Group B; National Cancer Institute (NCI); Radiation Therapy Oncology Group; American College of Surgeons; Southwest Oncology Group
Recruiting - verified March 2010
Condition: Attention Deficit Hyperactivity Disorder
Interventions: Drug: Ritalin; Drug: Placebo
Sponsor: McGill University
Recruiting - verified March 2010
Conditions: Neuropathic Pain; Multiple Sclerosis
Interventions: Drug: nabilone; Other: placebo
Sponsors: University of Manitoba; Valeant Pharmaceuticals North America
Recruiting - verified February 2010
Condition: Advanced Glenohumeral Arthritis
Intervention: Device: Humeral surface replacement hemiarthroplasty (CAP)
Sponsors: University of Calgary; DePuy International; Johnson & Johnson
Recruiting - verified March 2010
Condition: Myocardial Infarction
Intervention: Behavioral: Early hospital discharge facilitated by close nurse practitioner follow-up
Sponsors: Hamilton Health Sciences; McMaster University; Regional Medical Associates Research Scholarship Fund
Completed - verified February 2010
Condition: Type 1 Diabetes Mellitus
Intervention: Drug: Otelixizumab
Sponsors: Tolerx Inc.; Juvenile Diabetes Research Foundation
Recruiting - verified June 2009
Condition: Prostate Cancer
Intervention: Procedure: MRI Targeted Focal Thermal Therapy of Prostate Cancer
Sponsor: University Health Network, Toronto
Active, not recruiting - verified December 2006
Condition: Cystic Fibrosis
Interventions: Drug: azithromycin 250 mg tablets; Drug: placebo tablets
Sponsors: CF Therapeutics Development Network Coordinating Center; Cystic Fibrosis Foundation
Completed - verified February 2010
Conditions: Atrial Fibrillation; Catheter Ablation
Intervention: Other: Aggressive BP lowering
Sponsors: Capital District Health Authority, Canada; Nova Scotia Health Research Foundation
Recruiting - verified September 2009
Condition: Cerebral Palsy
Intervention: Procedure: Gait analysis in a motion laboratory
Sponsor: The Hospital for Sick Children
Recruiting - verified January 2007
Condition: Gangliosidoses GM2
Intervention: Drug: miglustat
Sponsors: The Hospital for Sick Children; Actelion
Active, not recruiting - verified January 2008
Conditions: Endometrial Cancer; Ovarian Cancer; Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: eribulin mesylate; Drug: gemcitabine hydrochloride
Sponsors: Princess Margaret Hospital, Canada; National Cancer Institute (NCI)
Recruiting - verified May 2007
Condition: Pain
Interventions: Drug: Fentanyl; Drug: Sterile water
Sponsor: The Hospital for Sick Children
Recruiting - verified January 2008
Condition: Stroke
Intervention: Behavioral: physical rehabilitation
Sponsors: Queen's University; Heart and Stroke Foundation of Ontario
Recruiting - verified February 2010
Condition: Esophageal Cancer
Interventions: Drug: Irinotecan; Drug: Cisplatin; Procedure: Radiation; Procedure: Surgery; Drug: sunitinib (Sutent)
Sponsors: University Health Network, Toronto; Pfizer
Recruiting - verified March 2010
Condition: Obsessive Compulsive Disorder
Interventions: Device: refractory transcranial magnetic stimulation (rTMS); Device: Sham condition
Sponsor: Centre for Addiction and Mental Health
Recruiting - verified February 2010
Condition: Supraventricular Tachycardia in Infants
Intervention: Drug: digoxin and propranolol
Sponsors: University of British Columbia; The Hospital for Sick Children; University of Utah
Recruiting - verified February 2010
Condition: Non-small Cell Lung Cancer
Intervention: Drug: Erlotinib
Sponsors: Ontario Clinical Oncology Group (OCOG); Roche Pharma AG
Recruiting - verified February 2010
Conditions: Breast Cancer; Cognitive/Functional Effects; Lung Cancer; Metastatic Cancer; Prostate Cancer
Interventions: Radiation: radiation therapy; Radiation: stereotactic radiosurgery
Sponsors: North Central Cancer Treatment Group; National Cancer Institute (NCI); American College of Surgeons; Eastern Cooperative Oncology Group; Radiation Therapy Oncology Group
Recruiting - verified March 2010
Condition: Breast Neoplasms
Interventions: Drug: CP-751,871 + exemestane; Drug: exemestane
Sponsors: Pfizer; Massachusetts General Hospital
Recruiting - verified March 2010
Condition: Non-small Cell Lung Cancer
Intervention: Procedure: Endobronchial Ultrasound Guided Transthoracic Needle Biopsy
Sponsor: University Health Network, Toronto
Recruiting - verified March 2010
Condition: Alcoholism
Intervention: Procedure: Internet personalized alcohol feedback (PAF)
Sponsors: Centre for Addiction and Mental Health; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Completed - verified March 2010
Condition: Smoking
Interventions: Drug: nicotine replacement; Behavioral: behavioural intervention
Sponsors: Centre for Addiction and Mental Health; Pfizer; Ontario Ministry of Health and Long Term Care
Recruiting - verified March 2010
Conditions: Atrial Fibrillation; Heart Valve Diseases; Venous Thrombosis
Intervention: Drug: Prolongation of the interval between monitoring of warfarin
Sponsors: Hamilton Health Sciences; The Physicians' Services Incorporated Foundation
Completed - verified December 2008
Conditions: Chronic Myeloproliferative Disorders; Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases
Interventions: Drug: azacitidine; Drug: belinostat
Sponsors: University of Chicago; National Cancer Institute (NCI)
Recruiting - verified April 2009
Conditions: Arthritis, Rheumatoid; Osteoarthritis
Interventions: Drug: celecoxib; Drug: Ibuprofen; Drug: Naproxen
Sponsors: Pfizer; The Cleveland Clinic
Recruiting - verified March 2010
Conditions: Anemia; Renal Failure
Interventions: Drug: Heme Iron Polypeptide (Proferrin); Drug: Iron sucrose (Venofer)
Sponsor: Ottawa Hospital Research Institute
Recruiting - verified March 2010
Condition: Shock, Traumatic
Interventions: Drug: 7.5% hypertonic saline/6% Dextran-70 (HSD); Drug: 7.5% hypertonic saline (HS); Drug: 0.9% normal saline
Sponsors: University of Washington; National Heart, Lung, and Blood Institute (NHLBI); National Institute of Neurological Disorders and Stroke (NINDS); The Institute of Circulatory and Respiratory Health (ICRH); Defence Research and Development Canada
Terminated - verified March 2010
Condition: Breast Cancer
Interventions: Drug: anastrozole; Drug: chemotherapy; Drug: exemestane; Drug: letrozole; Drug: tamoxifen citrate
Sponsors: Eastern Cooperative Oncology Group; National Cancer Institute (NCI); Southwest Oncology Group; Cancer and Leukemia Group B; American College of Surgeons; North Central Cancer Treatment Group; NCIC Clinical Trials Group; National Surgical Adjuvant Breast and Bowel Project (NSABP)
Recruiting - verified March 2010
Condition: Malignant Mesothelioma
Interventions: Drug: cediranib maleate; Other: laboratory biomarker analysis
Sponsors: University of Chicago; National Cancer Institute (NCI)
Recruiting - verified June 2007
Condition: Prostate Cancer
Interventions: Procedure: 7800 cGy/39 fractions in 8 weeks; Procedure: 6000 cGy/20 fractions in 4 weeks
Sponsors: Ontario Clinical Oncology Group (OCOG); Canadian Institutes of Health Research (CIHR); Trans-Tasman Radiation Oncology Group (TROG)
Recruiting - verified February 2010
Conditions: Cardiovascular Diseases; Vasodilation
Intervention: Behavioral: Nutrition
Sponsors: Laval University; Canadian Institutes of Health Research (CIHR)
Completed - verified February 2006
Condition: Breast Cancer
Interventions: Radiation: 3D-CRT APBI; Radiation: WBI
Sponsors: Ontario Clinical Oncology Group (OCOG); Canadian Institutes of Health Research (CIHR); Canadian Breast Cancer Research Alliance
Recruiting - verified March 2010
Condition: Scoliosis
Interventions: Procedure: Moss Miami Spine Instrumentation System; Procedure: Universal Spine Instrumentation System
Sponsors: The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR); Synthes Canada; DePuy-Acromed, Inc.; Johnson & Johnson
Completed - verified September 2006
Condition: Ovarian Cancer
Intervention: Drug: Exemestane
Sponsor: Ottawa Hospital Research Institute
Completed - verified March 2010
Condition: Sleep Deprivation
Intervention: Behavioral: counselling on maternal and infant sleep behavior
Sponsor: The Hospital for Sick Children
Active, not recruiting - verified September 2006
Condition: Atherosclerosis
Intervention: Drug: Clopidogrel 75 mg daily
Sponsors: University of Ottawa Heart Institute; Sanofi-Aventis; Bristol-Myers Squibb
Recruiting - verified March 2009
Condition: Malignant Pleural Effusions
Intervention: Behavioral: LCADLS, FACIT-PAL, FACIT-TS questionnaires
Sponsor: University Health Network, Toronto
Recruiting - verified March 2010
Conditions: Organ Transplantation; Immunosuppression
Intervention: Biological: varicella vaccine (VARIVAX)
Sponsor: The Hospital for Sick Children
Active, not recruiting - verified April 2006
Condition: Asthma, Bronchial
Interventions: Drug: Montelukast plus prednisolone; Drug: Prednisolone
Sponsors: The Hospital for Sick Children; Merck Frosst Canada Ltd.
Recruiting - verified September 2006
Condition: Glioma
Intervention: Drug: vinblastine sulphate injection
Sponsors: The Hospital for Sick Children; Ontario Cancer Research Network
Active, not recruiting - verified January 2008
Conditions: Pain; Infant, Newborn; Diabetes
Intervention: Drug: Sucrose
Sponsors: The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified September 2005
Conditions: Wounds and Injuries; Closed Head Injury
Intervention: Behavioral: school playgrounds
Sponsors: The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR)
Recruiting - verified October 2006
Condition: Kidney Failure, Chronic
Intervention: Drug: darbepoetin alfa
Sponsor: The Hospital for Sick Children
Active, not recruiting - verified February 2008
Condition: Idiopathic Toe Walking
Intervention: Drug: Botox injections
Sponsor: University of British Columbia
Recruiting - verified February 2010
Conditions: Organ Transplant; Immunosuppression
Interventions: Biological: 7-valent pneumococcal conjugate vaccine; Biological: Pneumococcal 7-valent Conjugate Vaccine
Sponsor: The Hospital for Sick Children
Active, not recruiting - verified April 2006
Condition: Kidney Transplantation
Intervention: Drug: sirolimus
Sponsors: University of Manitoba; Wyeth
Completed - verified February 2010
Condition: Non-small Cell Lung Cancer
Intervention: Procedure: Minimum Dose Computed Tomography (MnDCT) scan
Sponsor: University Health Network, Toronto
Recruiting - verified March 2010
Condition: Sarcoma
Interventions: Biological: PEG-interferon alfa-2b; Drug: cisplatin; Drug: doxorubicin hydrochloride; Drug: etoposide; Drug: ifosfamide; Drug: methotrexate
Sponsors: Children's Oncology Group; National Cancer Institute (NCI); University College London Hospitals
Recruiting - verified March 2010
Conditions: Bladder Diseases; Interstitial Cystitis
Interventions: Drug: Amitriptyline; Other: Placebo
Sponsors: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University of Pennsylvania
Active, not recruiting - verified March 2010
Condition: Lung Cancer
Interventions: Procedure: conventional surgery; Procedure: therapeutic thoracoscopy; Radiation: brachytherapy; Radiation: iodine I 125
Sponsors: American College of Surgeons; National Cancer Institute (NCI)
Active, not recruiting - verified January 2010
Condition: Head and Neck Cancer
Intervention: Drug: bortezomib
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Recruiting - verified June 2009
Condition: Leukemia
Interventions: Drug: cytarabine; Drug: daunorubicin hydrochloride; Drug: tipifarnib
Sponsors: Princess Margaret Hospital, Canada; National Cancer Institute (NCI)
Completed - verified May 2007
Condition: Breast Cancer
Interventions: Drug: exemestane; Drug: tamoxifen citrate
Sponsors: International Breast Cancer Study Group; National Cancer Institute (NCI); Breast International Group
Recruiting - verified March 2010
Condition: Breast Cancer
Interventions: Drug: exemestane; Drug: tamoxifen citrate; Drug: triptorelin; Procedure: oophorectomy; Radiation: radiation therapy
Sponsors: International Breast Cancer Study Group; National Cancer Institute (NCI); Breast International Group; Cancer and Leukemia Group B; NCIC Clinical Trials Group; North Central Cancer Treatment Group; National Surgical Adjuvant Breast and Bowel Project (NSABP); Southwest Oncology Group
Recruiting - verified March 2010
Conditions: Drug/Agent Toxicity by Tissue/Organ; Leukemia
Intervention: Dietary Supplement: silymarin
Sponsors: Herbert Irving Comprehensive Cancer Center; National Cancer Institute (NCI)
Active, not recruiting - verified May 2006
Condition: Lymphoma
Interventions: Biological: bleomycin sulfate; Biological: filgrastim; Biological: pegfilgrastim; Drug: ABVD regimen; Drug: BEACOPP regimen; Drug: cyclophosphamide; Drug: dacarbazine; Drug: doxorubicin hydrochloride; Drug: etoposide; Drug: prednisone; Drug: procarbazine hydrochloride; Drug: vinblastine; Drug: vincristine sulfate
Sponsors: European Organization for Research and Treatment of Cancer; Lymphoma Trials Office; Groupe d'Etudes de Lymphomes de L'Adulte; Grup per l'Estudi dels Limfomes de Catalunya i Balears; NCIC Clinical Trials Group; Australasian Leukaemia and Lymphoma Group (ALLG); Nordic Lymphoma Group
Active, not recruiting - verified June 2009
Condition: Epilepsy
Intervention: Biological: Natural Progesterone
Sponsors: Beth Israel Deaconess Medical Center; Brigham and Women's Hospital; Columbia University; Dartmouth-Hitchcock Medical Center; Emory University; Johns Hopkins University; MINCEP Epilepsy Care; Montreal Neurological Institute and Hospital; Ohio State University; Thomas Jefferson University; University of Maryland; University of Southern California; University of Virginia; Weill Medical College of Cornell University
Completed - verified March 2010
Condition: Sarcoma
Interventions: Biological: dactinomycin; Drug: busulfan; Drug: doxorubicin hydrochloride; Drug: etoposide; Drug: ifosfamide; Drug: melphalan; Drug: vincristine sulfate; Procedure: autologous hematopoietic stem cell transplantation; Procedure: conventional surgery; Radiation: radiation therapy
Sponsors: University Hospitals, Leicester; National Cancer Institute (NCI); Children's Cancer and Leukaemia Group; Societe Francaise Oncologie Pediatrique; European Organization for Research and Treatment of Cancer; Gesellschaft fur Padiatrische Onkologie und Hamatologie - Germany; Gesellschaft fur Padiatrische Onkologie und Hamatologie - Austria; Swiss Group for Clinical Cancer Research; EBMT Solid Tumors Working Party; Children's Oncology Group
Recruiting - verified March 2010
Condition: Breast Cancer
Interventions: Procedure: adjuvant therapy; Radiation: radiation therapy
Sponsors: NCIC Clinical Trials Group; National Cancer Institute (NCI); National Surgical Adjuvant Breast and Bowel Project (NSABP); Radiation Therapy Oncology Group; Southwest Oncology Group; Trans-Tasman Radiation Oncology Group (TROG); North Central Cancer Treatment Group
Active, not recruiting - verified March 2010
Conditions: Hypertension, Pulmonary; Respiratory Insufficiency; Infant, Newborn, Diseases; Meconium Aspiration; Persistent Fetal Circulation Syndrome; Pneumonia, Aspiration; Respiratory Distress Syndrome
Interventions: Drug: Inhaled nitric oxide; Drug: Placebo
Sponsors: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Medical Research Council of Canada
Terminated - verified November 2009
Condition: Lymphoma
Intervention: Biological: rituximab
Sponsors: University of California, Los Angeles; National Cancer Institute (NCI); Genentech
Completed - verified February 2010
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