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  • PeriOperative ISchemic Evaluation-2 Trial

    Condition:   Cardiovascular Disease
    Interventions:   Drug: Active Clonidine;   Drug: Placebo Clonidine;   Drug: Active ASA;   Drug: Placebo ASA
    Sponsor:   Hamilton Health Sciences
    Not yet recruiting - verified March 2010
  • Ablation Versus Anti-Arrhythmic (AA) Drug Therapy for AF - Pivotal Trial

    Conditions:   Atrial Fibrillation;   Arrhythmia;   Stroke Prevention;   Mortality
    Interventions:   Device: Left atrial ablation;   Drug: Rate or Rhythm Control Therapy
    Sponsors:   Mayo Clinic;   National Heart, Lung, and Blood Institute (NHLBI);   Duke University;   St. Jude Medical;   Biosense Webster, Inc.
    Recruiting - verified February 2010
  • A Trial of ABI-007 Versus Dacarbazine in Previously Untreated Patients With Metastatic Malignant Melanoma

    Condition:   Malignant Melanoma
    Interventions:   Drug: ABI-007;   Drug: Dacarbazine
    Sponsors:   Abraxis BioScience Inc.;   University of Arizona
    Recruiting - verified August 2009
  • Phase III Acute Coronary Syndrome

    Condition:   Acute Coronary Syndrome
    Interventions:   Drug: Apixaban;   Drug: Placebo
    Sponsors:   Bristol-Myers Squibb;   Pfizer;   Duke University
    Recruiting - verified October 2009
  • Comparison of Different Types of Surgery in Treating Patients With Stage IA Non-Small Cell Lung Cancer

    Condition:   Lung Cancer
    Interventions:   Procedure: thoracoscopic surgery;   Procedure: videothoracoscopy
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI);   Radiation Therapy Oncology Group;   American College of Surgeons;   Southwest Oncology Group
    Recruiting - verified March 2010
  • Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen

    Conditions:   Arthritis, Rheumatoid;   Osteoarthritis
    Interventions:   Drug: celecoxib;   Drug: Ibuprofen;   Drug: Naproxen
    Sponsors:   Pfizer;   The Cleveland Clinic
    Recruiting - verified February 2010
  • PROFIT - Prostate Fractionated Irradiation Trial

    Condition:   Prostate Cancer
    Interventions:   Procedure: 7800 cGy/39 fractions in 8 weeks;   Procedure: 6000 cGy/20 fractions in 4 weeks
    Sponsors:   Ontario Clinical Oncology Group (OCOG);   Canadian Institutes of Health Research (CIHR);   Trans-Tasman Radiation Oncology Group (TROG)
    Recruiting - verified February 2010
  • Post-operative Concurrent Chemo-radiotherapy Versus Post-operative Radiotherapy for Cancer of the Head and Neck

    Condition:   Skin Cancer
    Interventions:   Drug: Carboplatin;   Radiation: Radiotherapy
    Sponsors:   Trans-Tasman Radiation Oncology Group (TROG);   Princess Alexandra Hospital, Brisbane, Australia;   The Royal Australian and New Zealand College of Radiologists;   The Princess Alexandra Hospital Cancer Collaborative Group
    Recruiting - verified September 2009
  • Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma

    Condition:   Sarcoma
    Interventions:   Biological: PEG-interferon alfa-2b;   Drug: cisplatin;   Drug: doxorubicin hydrochloride;   Drug: etoposide;   Drug: ifosfamide;   Drug: methotrexate
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI);   University College London Hospitals
    Recruiting - verified March 2010
  • Improving Metabolic Assessments in Type 1 Diabetes Mellitus Clinical Trials

    Condition:   Diabetes Mellitus, Type 1
    Interventions:   Procedure: Mixed Meal Tolerance Test;   Procedure: Glucagon Stimulation Test
    Sponsors:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   National Institute of Allergy and Infectious Diseases (NIAID);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   Juvenile Diabetes Research Foundation;   National Center for Research Resources (NCRR)
    Completed - verified February 2010
  • Triptorelin With Either Exemestane or Tamoxifen in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

    Condition:   Breast Cancer
    Interventions:   Drug: exemestane;   Drug: tamoxifen citrate
    Sponsors:   International Breast Cancer Study Group;   National Cancer Institute (NCI);   Breast International Group
    Recruiting - verified March 2010
  • Suppression of Ovarian Function Plus Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

    Condition:   Breast Cancer
    Interventions:   Drug: exemestane;   Drug: tamoxifen citrate;   Drug: triptorelin;   Procedure: oophorectomy;   Radiation: radiation therapy
    Sponsors:   International Breast Cancer Study Group;   National Cancer Institute (NCI);   Breast International Group;   Cancer and Leukemia Group B;   NCIC Clinical Trials Group;   North Central Cancer Treatment Group;   National Surgical Adjuvant Breast and Bowel Project (NSABP);   Southwest Oncology Group
    Recruiting - verified March 2010
  • Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Stage III or Stage IV Hodgkin's Lymphoma

    Condition:   Lymphoma
    Interventions:   Biological: bleomycin sulfate;   Biological: filgrastim;   Biological: pegfilgrastim;   Drug: ABVD regimen;   Drug: BEACOPP regimen;   Drug: cyclophosphamide;   Drug: dacarbazine;   Drug: doxorubicin hydrochloride;   Drug: etoposide;   Drug: prednisone;   Drug: procarbazine hydrochloride;   Drug: vinblastine;   Drug: vincristine sulfate
    Sponsors:   European Organization for Research and Treatment of Cancer;   Lymphoma Trials Office;   Groupe d'Etudes de Lymphomes de L'Adulte;   Grup per l'Estudi dels Limfomes de Catalunya i Balears;   NCIC Clinical Trials Group;   Australasian Leukaemia and Lymphoma Group (ALLG);   Nordic Lymphoma Group
    Active, not recruiting - verified June 2009

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