Nervous System Diseases

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Paid Clinical Trials - : Nervous System Diseases

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  • Chemotherapy-Induced Peripheral Neuropathy Survey

    Conditions:   Breast Cancer;   Colorectal Cancer;   Myeloma;   Chemotherapy-Induced Peripheral Neuropathy
    Interventions:   Behavioral: Questionnaire;   Behavioral: Sensory Tests;   Behavioral: Interview
    Sponsor:   M.D. Anderson Cancer Center
    Not yet recruiting - verified November 2009
  • New Perspectives in the Rehabilitation of Children With Motor Disorders : the Role of the Mirror Neuron System

    Conditions:   Hemiplegia;   Cerebral Palsy
    Interventions:   Other: action observation therapy;   Other: repetition of gestures
    Sponsors:   University of Modena and Reggio Emilia;   University of Parma
    Recruiting - verified November 2009
  • Optimal Planning Target Volume With Stereotactic Radiosurgery

    Conditions:   Brain Neoplasms;   Brain Cancer
    Intervention:   Radiation: Stereotactic Radiosurgery
    Sponsor:   Duke University
    Not yet recruiting - verified November 2009
  • Safety Study of Carbamylated Erythropoietin to Treat Patients With the Neurodegenerative Disorder Friedreich's Ataxia

    Condition:   Friedreich's Ataxia
    Interventions:   Drug: Lu AA24493;   Drug: Placebo
    Sponsor:   H. Lundbeck A/S
    Recruiting - verified November 2009
  • Safety and Tolerability of the Ketogenic Diet in Amyotrophic Lateral Sclerosis (ALS)

    Condition:   Amyotrophic Lateral Sclerosis
    Intervention:   Dietary Supplement: KetoCal
    Sponsors:   Johns Hopkins University;   Nutricia North America;   Cornell University
    Recruiting - verified November 2009
  • Evaluation of Treatment Satisfaction and Preference for Sumavel DosePro in the Treatment of Migraine

    Condition:   Migraine
    Intervention:   Device: Sumavel DosePro
    Sponsor:   Zogenix, Inc.
    Not yet recruiting - verified November 2009
  • Treximet Early Intervention Adolescent Migraine

    Condition:   Adolescent Migraine
    Intervention:   Drug: Treximet
    Sponsors:   Premiere Research Institute;   GlaxoSmithKline
    Not yet recruiting - verified November 2009
  • Vyvanse and Glucose Intolerance in Children With Attention Deficit Hyperactivity Disorder (ADHD) and Obesity

    Conditions:   Attention Deficit Hyperactivity Disorder;   Glucose Intolerance;   Obesity
    Intervention:   Drug: Lis-dexamphetamine
    Sponsors:   Duke University;   Shire Pharmaceutical Development
    Not yet recruiting - verified November 2009
  • Observational Study on the Long Term Safety of Kuvan® Treatment in Patients With Hyperphenylalaninemia (HPA) Due to Phenylketonuria (PKU) or BH4 Deficiency

    Condition:   Hyperphenylalaninemia (HPA) Due to Phenylketonuria (PKU) or Tetrahydrobiopterin (BH4) Deficiency
    Intervention:  
    Sponsor:   Merck KGaA
    Not yet recruiting - verified November 2009
  • Multi-centre UK Study of the Acetylcholinesterase Inhibitor Donepezil in Early Dementia Associated With Parkinson's Disease

    Condition:   Parkinson's Disease
    Intervention:   Drug: Donepezil
    Sponsors:   Newcastle-upon-Tyne Hospitals NHS Trust;   Institute of Health & Society, Newcastle University;   University of Cambridge;   University of Manchester;   University of Birmingham and City Hospital;   Llandudno Hospital and School of Medical Science, Bangor University;   London School of Economics and Political Science;   University College, London;   Lancashire Care Trust;   Institute for Ageing and Health, Newcastle University;   King's College London
    Not yet recruiting - verified November 2009
  • Whole Brain Radiotherapy With or Without Temozolomide at Daily Fixed-dose for Brain Metastases Treatment

    Condition:   Brain Neoplasms
    Interventions:   Drug: Temozolomide;   Radiation: Whole brain radiotherapy
    Sponsor:   Instituto Nacional de Cancerologia de Mexico
    Completed - verified November 2009
  • Carpal Tunnel Syndrome Release Using PSU Retractor

    Condition:   Carpal Tunnel Syndrome
    Intervention:   Procedure: Limited incision using PSU retractor
    Sponsor:   Prince of Songkla University
    Enrolling by invitation - verified November 2009
  • Oxycodone for Labor Pain - Pharmacokinetics (PK), Safety and Efficacy

    Condition:   Labor Pain
    Intervention:   Drug: Oxycodone
    Sponsor:   Kuopio University Hospital
    Not yet recruiting - verified November 2009
  • Orientation for Hearing Aid Users: Information Retention

    Condition:   Hearing Loss
    Intervention:   Behavioral: Counseling
    Sponsor:   University of Sao Paulo
    Completed - verified November 2009
  • Short and Long Term Efficacy of Combined Cabergoline and Octreotide Treatment in Acromegalic Patients

    Condition:   Acromegaly
    Intervention:   Drug: cabergoline
    Sponsor:   Federal University of São Paulo
    Completed - verified November 2009
  • A Safety and Dose Finding Study of Plasmin (Human) Administered Into the Middle Cerebral Artery of Stroke Patients

    Condition:   Acute Ischemic Stroke
    Interventions:   Biological: Plasmin (Human);   Biological: Plasmin (Human);   Biological: Plasmin (Human)
    Sponsor:   Talecris Biotherapeutics
    Recruiting - verified November 2009
  • The Effect of High-dose Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers (HighDose RemiSun)

    Condition:   Hyperalgesia
    Interventions:   Drug: Remifentanil;   Drug: Midazolam
    Sponsor:   Medical University of Vienna
    Recruiting - verified November 2009
  • A Study With RO4917523 in Patients With Fragile X Syndrome

    Condition:   Fragile X Syndrome
    Interventions:   Drug: RO4917523;   Drug: Placebo;   Drug: RO4917523;   Drug: Placebo
    Sponsor:   Hoffmann-La Roche
    Not yet recruiting - verified November 2009
  • Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence

    Conditions:   Alcohol Dependence;   Insomnia
    Interventions:   Drug: Gabapentin or placebo dispensed to subject.;   Drug: Gabapentin or placebo dispensed to subject.
    Sponsors:   University of Michigan;   National Institutes of Health (NIH);   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting - verified November 2009
  • The Roles of Prostanoids in Patients With Sleep Apnea Syndrome

    Conditions:   Sleep Apnea;   Continuous Positive Airway Pressure
    Intervention:   Device: CPAP treatment
    Sponsor:   Kyoto University, Graduate School of Medicine
    Not yet recruiting - verified November 2009
  • PSU Lumbar Support for Prevention of Low Back Pain in Rubber Tapper

    Condition:   Low Back Pain
    Intervention:   Device: PSU lumbar back support
    Sponsor:   Prince of Songkla University
    Not yet recruiting - verified November 2009
  • A Pilot Study of Bevacizumab (Avastin) in Patients With Unresectable or Recurrent Hemangioblastoma From Von-Hippel-Lindau Disease

    Conditions:   Hemangioblastomas;   Von Hippel Lindau Disease
    Intervention:   Drug: Avastin
    Sponsors:   Dartmouth-Hitchcock Medical Center;   Genentech
    Not yet recruiting - verified November 2009
  • Angiotensin-converting Enzyme (ACE)-Inhibition and Mechanisms of Skeletal Muscle Weakness in Chronic Obstructive Pulmonary Disease (COPD)

    Condition:   Chronic Obstructive Pulmonary Disease
    Interventions:   Drug: Fosinopril;   Other: lactose
    Sponsors:   Imperial College London;   Medical Research Council
    Recruiting - verified November 2009
  • Transversus Abdominis Plane (TAP) Block for Cesarean Section

    Condition:   Hyperalgesia, Secondary
    Interventions:   Procedure: TAP Block;   Procedure: TAP Block;   Procedure: TAP Block
    Sponsor:   University of Washington
    Recruiting - verified November 2009
  • Mission Connect Mild Traumatic Brain Injury (TBI) Integrated Clinical Protocol

    Conditions:   Mild Traumatic Brain Injury;   Post-Traumatic Stress Disorder
    Interventions:   Drug: Atorvastatin;   Drug: Placebo
    Sponsors:   Baylor College of Medicine;   The University of Texas Health Science Center, Houston
    Not yet recruiting - verified November 2009
  • Non-contact Boxing Training and Traditional Therapeutic Exercise for Persons With Parkinson's Disease

    Condition:   Parkinson's Disease
    Interventions:   Behavioral: Traditional Therapeutic Exercise;   Behavioral: Non-Contact Boxing Training
    Sponsor:   University of Indianapolis
    Recruiting - verified November 2009
  • Multi-Site Evaluation of Progressive Tinnitus Management

    Condition:   Tinnitus
    Interventions:   Procedure: Progressive Tinnitus Management;   Procedure: Usual Care
    Sponsor:   Department of Veterans Affairs
    Not yet recruiting - verified November 2009
  • Acupuncture in Patients With Carpal Tunnel Syndrome ~ A Randomized Controlled Trial

    Condition:   Carpal Tunnel Syndrome
    Interventions:   Other: Acupuncture;   Drug: Prednisolone
    Sponsor:   Kuang Tien General Hospital
    Completed - verified November 2009
  • Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors

    Conditions:   Brain Cancer;   Choroid Plexus Tumors
    Interventions:   Drug: Carboplatin;   Drug: Cisplatin;   Drug: Cyclophosphamide;   Drug: Dactinomycin;   Drug: Doxorubicin;   Drug: Etoposide;   Drug: Irinotecan;   Drug: Leucovorin;   Drug: Methotrexate;   Drug: Temozolomide;   Drug: Vincristine
    Sponsor:   M.D. Anderson Cancer Center
    Recruiting - verified November 2009
  • Delayed Versus Early Enoxaparin Prophylaxis After Traumatic Brain Injury (TBI)

    Conditions:   Venous Thromboembolism;   Traumatic Brain Injury
    Interventions:   Drug: enoxaparin;   Drug: placebo
    Sponsor:   University of Texas Southwestern Medical Center
    Recruiting - verified November 2009
  • Huperzine-A to Help With Mental Problems and the Inability to Care for Onself in Patients With Schizophrenia

    Conditions:   Schizophrenia;   Dementia
    Intervention:   Drug: Huperzine A
    Sponsors:   VA Nebraska Western Iowa Health Care System;   American Legion of Iowa Foundation
    Not yet recruiting - verified November 2009
  • Carotid and Vertebral Magnetic Resonance Angiography (MRA) Study Comparing Dotarem and Time Of Flight (TOF)

    Conditions:   Carotid Arterial Disease;   Vertebral Arterial Disease
    Intervention:   Drug: Dotarem
    Sponsor:   Guerbet
    Recruiting - verified November 2009
  • An Escalating Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of LNK 754 in Elderly Volunteers and in Subjects With Mild Alzheimer's Disease

    Condition:   Mild Alzheimer's Disease
    Interventions:   Drug: LNK-754;   Drug: Placebo
    Sponsor:   Link Medicine Corporation
    Recruiting - verified November 2009
  • Efficacy and Safety Clinical Trial of the Combination of Acetylsalicylic Acid, Sodium Bicarbonate and Citric Acid, Produced by Geolab Pharmaceutical Industries Ltd., Compared to Acetylsalicylic Acid (Aspirin ® - Bayer) in Patients With Episodic Tension-type Headache.

    Condition:   Treatment of Episodic Tension Headache
    Interventions:   Drug: Association: acetylsalicylic acid (500mg), sodium bicarbonate (1625) and citric acid (965);   Drug: Aspirin - Bayer
    Sponsor:   L.A.L Clinica Pesquisa e Desenvolvimento Ltda.
    Not yet recruiting - verified November 2009
  • External Beam Radiation Therapy and Cetuximab Followed by Irinotecan and Cetuximab for Children and Young Adults With Newly Diagnosed Diffuse Pontine Tumors and High-Grade Astrocytomas

    Condition:   Brain Cancer
    Intervention:   Other: cetuximab in conjunction with external beam radiation therapy, followed by cetuximab and irinotecan
    Sponsors:   Memorial Sloan-Kettering Cancer Center;   Children's Healthcare of Atlanta;   Dana-Farber Cancer Institute;   M.D. Anderson Cancer Center;   Phoenix Children's Hospital;   Sidney Kimmel Comprehensive Cancer Center;   Alberta Children's Hospital;   University of Colorado at Denver and Health Sciences Center;   University of Florida;   Vanderbilt University
    Recruiting - verified November 2009
  • PreventIon of CArdiovascular Events in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage

    Conditions:   Brain Ischemia;   Intracranial Hemorrhages
    Interventions:   Drug: Cilostazol;   Drug: Probucol;   Drug: Aspirin;   Drug: placebo of cilostazol;   Drug: placebo of aspirin;   Device: ankle-brachial index (ABI);   Device: intima-medial thickness (IMT);   Device: new asymptomatic brain hemorrhage;   Device: new ischemic lesions on follow-up FLAIR images
    Sponsors:   Asan Medical Center;   Korea Otsuka International Asia Arab
    Recruiting - verified November 2009
  • Discontinuation Study of the Durability of Effect of Milnacipran for the Treatment of Fibromyalgia

    Condition:   Fibromyalgia
    Interventions:   Drug: Placebo;   Drug: Milnacipran
    Sponsors:   Forest Laboratories;   Cypress Bioscience, Inc.
    Enrolling by invitation - verified November 2009
  • Prospective Observational Long-term Safety Registry of Multiple Sclerosis Patients Who Have Participated in Cladribine Clinical Trials

    Condition:   Multiple Sclerosis
    Intervention:  
    Sponsor:   EMD Serono
    Recruiting - verified November 2009
  • Bevacizumab, Temozolomide, and External Beam Radiation Therapy as First-Line Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

    Condition:   Brain and Central Nervous System Tumors
    Interventions:   Biological: bevacizumab;   Drug: temozolomide;   Genetic: gene expression analysis;   Other: laboratory biomarker analysis;   Procedure: adjuvant therapy;   Radiation: external beam radiation therapy
    Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
    Recruiting - verified November 2009
  • In Vivo Confocal Microscopy Tumor Atlas Study

    Condition:   Brain Neoplasms
    Intervention:   Device: Endomicroscope
    Sponsor:   Carl Zeiss Surgical GmbH
    Recruiting - verified November 2009
  • A Safety/Proof of Concept Study to Evaluate the Effects of Oral QLT091001 in Children With Leber Congenital Amaurosis (LCA)

    Condition:   Visual Impairment Due to Leber Congenital Amaurosis (LCA)
    Intervention:   Drug: QLT091001
    Sponsor:   QLT Inc
    Recruiting - verified November 2009
  • An Open Label Extension Study of STX209 in Subjects With Fragile X Syndrome

    Condition:   Fragile X Syndrome
    Intervention:   Drug: Arbaclofen
    Sponsor:   Seaside Therapeutics, LLC
    Enrolling by invitation - verified November 2009
  • Feasibility of a Trial Evaluating the Effectiveness of Occupational Therapy in Parkinson's Disease

    Condition:   Parkinson's Disease
    Intervention:   Other: occupational therapy
    Sponsors:   Radboud University;   Stichting Nuts Ohra
    Recruiting - verified November 2009
  • Metoclopramide Versus Ketorolac for Tension-type Headache

    Condition:   Headache
    Interventions:   Drug: Metoclopramide;   Drug: Ketorolac
    Sponsor:   Montefiore Medical Center
    Recruiting - verified November 2009
  • Influence of a Dietary Supplement as Treatment of Migraine in Children and Adolescents

    Condition:   Migraine
    Intervention:   Dietary Supplement: Migra 3
    Sponsor:   Complen Health GmbH
    Not yet recruiting - verified November 2009
  • Safety Study of Erythropoietin (EPO) in Parkinson's Disease

    Condition:   Parkinson Disease
    Intervention:   Drug: Erythropoietin human recombinant (EPOrh)
    Sponsor:   International Center for Neurological Restoration, Cuba
    Completed - verified November 2009
  • Nexus Compliance Study

    Condition:   Obstructive Sleep Apnea
    Interventions:   Device: Nexus CPAP;   Device: CPAP
    Sponsor:   ResMed
    Not yet recruiting - verified November 2009
  • Lisdexamfetamine Dimesylate Pilot Cognition Study to Evaluate the Utility of a Standardized Battery of Tests in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)

    Condition:   Attention-Deficit Hyperactivity Disorder
    Interventions:   Drug: Lisdexamfetamine Dimesylate;   Drug: Immediate Release Mixed Amphetamine Salts;   Drug: LDX Placebo + MAS-IR Placebo
    Sponsor:   Shire Pharmaceutical Development
    Not yet recruiting - verified November 2009
  • Use of Tendon Vibration and Mirror for the Improvement of Upper Limb Function and Pain Reduction

    Conditions:   Stroke;   Hemiplegia
    Interventions:   Device: Vibration and Mirror;   Device: Mirror therapy;   Device: no mirror, sham vibration
    Sponsor:   Hadassah Medical Organization
    Not yet recruiting - verified November 2009
  • Efficacy of Bupropion for ADHD in Adults

    Conditions:   Attention-Deficit/Hyperactivity Disorder;   Substance Use Disorders
    Intervention:   Drug: Bupropion Sustained Release (SR)
    Sponsor:   National Institute on Drug Abuse (NIDA)
    Completed - verified November 2009
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