Metabolic Disease

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Paid Clinical Trials - : Metabolic Disease

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  • Vyvanse and Glucose Intolerance in Children With Attention Deficit Hyperactivity Disorder (ADHD) and Obesity

    Conditions:   Attention Deficit Hyperactivity Disorder;   Glucose Intolerance;   Obesity
    Intervention:   Drug: Lis-dexamphetamine
    Sponsors:   Duke University;   Shire Pharmaceutical Development
    Not yet recruiting - verified November 2009
  • Iron Oligosaccharide in Inflammatory Bowel Disease Subjects With Iron Deficiency Anaemia

    Condition:   Inflammatory Bowel Disease
    Interventions:   Drug: Monofer;   Drug: Iron Sulphate
    Sponsors:   Pharmacosmos A/S;   Max Neeman International
    Recruiting - verified November 2009
  • A Phase 3 Study in Patients With Chronic Kidney Disease and Hyperphosphatemia on Peritoneal Dialysis

    Conditions:   Chronic Kidney Disease;   Renal Dialysis;   Renal Insufficiency
    Intervention:   Drug: ASP1585
    Sponsor:   Astellas Pharma Inc
    Not yet recruiting - verified November 2009
  • A Study With RO5095932 in Patients With Type 2 Diabetes on Stable Metformin Therapy

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Drug: RO5095932;   Drug: Placebo;   Drug: RO5095932;   Drug: Placebo
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009
  • Low Doses Corticosteroids as Adjuvant Therapy for the Treatment of Severe H1N1 Flu

    Conditions:   Pneumonia, Viral;   Influenza A Virus, H1N1 Subtype
    Interventions:   Drug: hydrocortisone;   Drug: isotonic saline
    Sponsors:   University of Versailles;   Assistance Publique - Hôpitaux de Paris
    Not yet recruiting - verified November 2009
  • Real-Time Continuous Glucose Monitoring in Pre-School Children With Type-1 Diabetes Mellitus

    Condition:   Diabetes Mellitus
    Intervention:   Device: Guardian RT
    Sponsor:   Sheba Medical Center
    Recruiting - verified November 2009
  • Diabetes Support Project: Couples Intervention

    Condition:   Type 2 Diabetes
    Interventions:   Behavioral: Telephone support and behavior change;   Other: Diabetes self-management education
    Sponsor:   State University of New York - Upstate Medical University
    Not yet recruiting - verified November 2009
  • Microcirculation Assessment in Diabetes and Metabolic Syndrome

    Conditions:   Coronary Microvascular Dysfunction;   Metabolic Syndrome;   Diabetes
    Intervention:   Other: Coronary microcirculation assessment
    Sponsor:   S.M. Misericordia Hospital
    Recruiting - verified November 2009
  • Safety Study of Carbamylated Erythropoietin to Treat Patients With the Neurodegenerative Disorder Friedreich's Ataxia

    Condition:   Friedreich's Ataxia
    Interventions:   Drug: Lu AA24493;   Drug: Placebo
    Sponsor:   H. Lundbeck A/S
    Recruiting - verified November 2009
  • Observational Study on the Long Term Safety of Kuvan® Treatment in Patients With Hyperphenylalaninemia (HPA) Due to Phenylketonuria (PKU) or BH4 Deficiency

    Condition:   Hyperphenylalaninemia (HPA) Due to Phenylketonuria (PKU) or Tetrahydrobiopterin (BH4) Deficiency
    Intervention:  
    Sponsor:   Merck KGaA
    Not yet recruiting - verified November 2009
  • Efficacy and Safety of Frequently Modified Intensive Insulin

    Condition:   Diabetes
    Intervention:   Drug: Intensive insulin therapy
    Sponsors:   Hygieia, Inc;   TKL Research, Inc.
    Completed - verified November 2009
  • Investigating the Accuracy of the Home Glucose Monitors in Hypoglycemia

    Condition:   Hypoglycemia
    Interventions:   Drug: Human insulin;   Drug: Human Insulin
    Sponsor:   Gulhane School of Medicine
    Completed - verified November 2009
  • Self Titration With Apidra to Reach Target Study (START)

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Drug: insulin glargine;   Drug: Apidra (insulin glulisine)
    Sponsor:   Sanofi-Aventis
    Recruiting - verified November 2009
  • Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease

    Conditions:   Coronary Artery Disease;   Chronic Kidney Disease;   Hypovitaminosis D;   Secondary Hyperparathyroidism
    Interventions:   Drug: paricalcitol;   Drug: placebo
    Sponsors:   Thomas Jefferson University;   Abbott
    Recruiting - verified November 2009
  • Different Metabolic Effects of Statins

    Condition:   Hypercholesterolemia
    Intervention:   Drug: pravastatin, rosuvastatin
    Sponsor:   Gachon University Gil Medical Center
    Recruiting - verified November 2009
  • A Study to Evaluate the Effects of Laropiprant on the Antiplatelet Effects of Clopidogrel and Aspirin in Combination

    Conditions:   Primary Hypercholesterolemia;   Mixed Hyperlipidemia
    Interventions:   Drug: niacin (+) laropiprant;   Drug: Comparator: aspirin;   Drug: Comparator: clopidogrel;   Drug: Comparator: laropiprant;   Drug: Comparator: placebo
    Sponsor:   Merck
    Not yet recruiting - verified November 2009
  • Linagliptin 2.5 mg Twice Daily Versus 5 mg Once Daily as add-on Therapy to Twice Daily Metformin in Type 2 Diabetes

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Drug: linagliptin;   Drug: placebo
    Sponsor:   Boehringer Ingelheim Pharmaceuticals
    Recruiting - verified November 2009
  • Effect of Angiotensin Receptor Blockade on Insulin Resistance and Adipose Tissue Cytokines in Type 2 Diabetes

    Conditions:   Insulin Resistance;   Type 2 Diabetes
    Interventions:   Procedure: Hyperinsulinaemia;   Drug: Losartan;   Procedure: Saline
    Sponsors:   Institute for Clinical and Experimental Medicine;   Ministry of Health, Czech Republic
    Completed - verified November 2009
  • A Phase IIb 78-week Study in Patients on a Basal Insulin +/- Metformin and/or Sulfonylurea and Are Not at Goal to Add BI 10773 vs. Placebo

    Condition:   Diabetes Mellitus, Type 2
    Intervention:   Drug: BI 10773
    Sponsor:   Boehringer Ingelheim Pharmaceuticals
    Recruiting - verified November 2009
  • Comparison of High-Dose Rosuvastatin Versus Low Statin Dose Plus Fenofibrate Versus Low Statin Dose Plus Niacin in the Treatment of Mixed Hyperlipidemia

    Condition:   Dyslipidemia
    Interventions:   Drug: High-dose rosuvastatin;   Drug: Statin plus fenofibrate;   Drug: Statin plus niacin ER/laropiprant
    Sponsor:   University of Ioannina
    Recruiting - verified November 2009
  • Boosted Lexiva With Lovaza Adjunctive Therapy in Hypertriglyceridemic, HIV-Infected Subjects

    Conditions:   Hypertriglyceridemia;   HIV Infection
    Interventions:   Dietary Supplement: Lovaza;   Drug: fosamprenavir/ritonavir
    Sponsors:   Felizarta, Franco, M.D.;   GlaxoSmithKline
    Recruiting - verified November 2009
  • Two Pieces of Fruit to Type 2 Diabetics?

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Behavioral: dietary treatment;   Behavioral: dietary treatment
    Sponsor:   Hospitalsenheden Vest
    Recruiting - verified November 2009
  • Using Cinacalcet to Treat the Hypophosphatemia of Early Kidney Transplant

    Conditions:   Hypophosphatemia;   Renal Transplant
    Interventions:   Drug: Cinacalcet;   Drug: Placebo
    Sponsor:   Montefiore Medical Center
    Recruiting - verified November 2009
  • Physician Perceptions About Parenteral Hydration in Latin America and Spain

    Conditions:   Dehydration;   Advanced Cancers
    Intervention:   Behavioral: Survey
    Sponsor:   M.D. Anderson Cancer Center
    Not yet recruiting - verified November 2009
  • Identification of Celiac Ganglia

    Condition:   Celiac Ganglia
    Intervention:  
    Sponsor:   Indiana University
    Enrolling by invitation - verified November 2009
  • Cholesterol Metabolism and Lipid Transfer in Diabetes

    Condition:   Type 2 Diabetes Mellitus
    Intervention:   Other: Plasma kinetic study
    Sponsors:   University of Sao Paulo General Hospital;   Fundação de Amparo à Pesquisa do Estado de São Paulo
    Completed - verified November 2009
  • Trial of Two Dietary Programs on Cardiometabolic Risk Factors in Subjects With Metabolic Syndrome

    Conditions:   Metabolic Syndrome;   Overweight;   Obesity;   Hypercholesterolemia
    Interventions:   Dietary Supplement: UltraMealPlus 360 (Medical food);   Other: Low-glycemic-load diet
    Sponsors:   MetaProteomics LLC;   University of Florida;   University of Connecticut;   University of California, Irvine
    Active, not recruiting - verified November 2009
  • Evaluation of a Diabetes-specific Cognitive Behavioural Treatment for Subthreshold Depression

    Conditions:   Depressive Symptoms;   Diabetes Mellitus
    Interventions:   Behavioral: Diabetes-Specific Cognitive-Behavioral Group Sessions;   Behavioral: Educative Group Lesson and Discussion
    Sponsors:   Forschungsinstitut der Diabetes Akademie Mergentheim;   Deutsches Diabetes-Zentrum (German Diabetes-Center) Duesseldorf;   University of Gießen, Departement of Psychosomatics;   Koordinierungszentrum fuer Klinische Studien (KKS), University of Duesseldorf
    Not yet recruiting - verified November 2009
  • Comparison of NN5401 With Biphasic Insulin Aspart 30 in Type 2 Diabetes

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Drug: NN5401;   Drug: biphasic insulin aspart 30
    Sponsor:   Novo Nordisk
    Recruiting - verified November 2009
  • Electronic Feedback on Diabetic Care to General Practitioners

    Condition:   Type 2 Diabetes
    Intervention:   Device: Electronic feedback system on diabetes care
    Sponsor:   University of Aarhus
    Completed - verified November 2009
  • A Clinical Investigation to Evaluate Negative Pressure Wound Therapy (NPWT) System in the Treatment of Diabetic Foot Ulcers (DFUs) Including Post Amputation Wounds Associated With Diabetes

    Conditions:   Diabetes;   Foot Ulcers
    Intervention:   Procedure: AvanceTM NPWT System
    Sponsor:   Molnlycke Health Care AB
    Not yet recruiting - verified November 2009
  • Prevent/Delay Development of Type 2 Diabetes in Subjects With Impaired Glucose Homeostasis Treated With Acarbose in Primary Care

    Condition:   Diabetes Mellitus
    Interventions:   Drug: Acarbose (Glucobay, BAYG5421);   Drug: Placebo
    Sponsor:   Bayer
    Completed - verified November 2009
  • Partners for Better Health in Adolescent Type 2 Diabetes: The Buddy Study

    Conditions:   Obesity;   Diabetes Mellitus, Type 2;   Abnormal Glucose Metabolism;   Type 2 Diabetes
    Intervention:   Behavioral: Assignment of a Lay Patient Partner
    Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    Recruiting - verified September 2009
  • Assessment of Insulin Resistance, NAFLD, Predictors of CV Morbidity, and Subcutaneous Adipose and Visceral Adipose Gene Expression in Patients Undergoing Gastric Bypass Surgery

    Conditions:   Morbid Obesity;   Insulin Resistance;   Non-Alcoholic Fatty Liver Disease
    Intervention:  
    Sponsors:   University of Massachusetts;   Worcester Foundation for Biomedical Research
    Recruiting - verified November 2009
  • Flaxseed Compared With Placebo in Patients With Hypercholesterolemia

    Condition:   Familial or Severe Hypercholesterolemia
    Interventions:   Dietary Supplement: flaxseed;   Dietary Supplement: whole wheat flour
    Sponsor:   The Hospital for Sick Children
    Recruiting - verified November 2009
  • Computerized Glucose Control in Critically Ill Patients

    Conditions:   Hyperglycemia;   Critical Illness
    Interventions:   Device: CGAO-based Glucose Control;   Device: Standard-Care Glucose Control
    Sponsors:   Centre Hospitalier of Chartres;   Société Française d'Anesthésie et de Réanimation (SFAR);   Baxter Healthcare Corporation
    Recruiting - verified November 2009
  • Efficacy of DLBS-32 in Subjects With Type-II Diabetes Mellitus

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Drug: DLBS-32;   Drug: DLBS-32;   Drug: DLBS-32;   Drug: DLBS-32;   Drug: Placebo capsule
    Sponsor:   Dexa Medica Group
    Recruiting - verified October 2009
  • A New Treatment Strategy of Adding Exenatide to Insulin Therapy for Patients With Type 2 Diabetes (t2DM) and Non-Alcoholic Fatty Liver Disease (NAFLD)

    Conditions:   Nonalcoholic Fatty Liver Disease;   Type 2 Diabetes Mellitus
    Intervention:   Drug: Exenatide
    Sponsors:   The University of Texas Health Science Center at San Antonio;   Amylin Pharmaceuticals, Inc.
    Active, not recruiting - verified November 2009
  • Efficacy and Safety of TAK-875 in Subjects With Type 2 Diabetes Mellitus

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Drug: TAK-875 6.25 mg;   Drug: TAK-875 25 mg;   Drug: TAK-875 50 mg;   Drug: TAK-875 100 mg;   Drug: TAK-875 200 mg;   Drug: Glimepiride 2 mg or 4mg;   Drug: Placebo
    Sponsor:   Takeda Global Research & Development Center, Inc.
    Not yet recruiting - verified November 2009
  • Effect of Probiotics in Treatment of Minimal Hepatic Encephalopathy (MHE) and Health Related Quality of Life

    Conditions:   Chronic Liver Disease;   Minimal Hepatic Encephalopathy
    Interventions:   Drug: VSL#3;   Drug: Lactulose
    Sponsors:   CD Pharma India Pvt. Ltd.;   Indian Council of Medical Research;   All India Institute of Medical Sciences, New Delhi
    Recruiting - verified November 2009
  • A Study of LY2189265 in Japanese Patients With Type 2 Diabetes

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Drug: LY2189265;   Drug: Placebo
    Sponsor:   Eli Lilly and Company
    Recruiting - verified November 2009
  • Saxagliptin Compared to Glimepiride in Elderly Type 2 Diabetes Patients, With Inadequate Glycemic Control on Metformin

    Condition:   Type 2 Diabetes Mellitus
    Interventions:   Drug: Saxagliptin;   Drug: Glimepiride
    Sponsors:   AstraZeneca;   Bristol-Myers Squibb
    Recruiting - verified November 2009
  • Efficacy and Tolerability of Saxagliptin add-on Compared to Uptitration of Metformin in Patients With Type 2 Diabetes

    Condition:   Type 2 Diabetes Mellitus
    Interventions:   Drug: Saxagliptin;   Drug: Metformin
    Sponsors:   AstraZeneca;   Bristol-Myers Squibb
    Recruiting - verified November 2009
  • Pivotal Study of Safety, Efficacy, Pharmacokinetics/Pharmacodynamics (PK/PD) of RP103 Compared to Cystagon® in Patients With Cystinosis

    Condition:   Cystinosis
    Interventions:   Drug: Cystagon® (Cysteamine Bitartrate);   Drug: RP103
    Sponsor:   Raptor Pharmaceutical Corp.
    Not yet recruiting - verified October 2009
  • A Trial Investigating the NN1250 Concentration-time Curve in Subjects With Various Degrees of Renal Impairment and in Subjects With Normal Renal Function

    Condition:   Diabetes Mellitus
    Interventions:   Drug: NN1250;   Drug: NN1250;   Drug: NN1250;   Drug: NN1250;   Drug: NN1250
    Sponsor:   Novo Nordisk
    Recruiting - verified November 2009
  • Comparison Between Low Carbohydrate Diet and Traditionally Recommended Diabetic Diet in the Treatment of Diabetes Mellitus Type 2.

    Condition:   Diabetes
    Interventions:   Dietary Supplement: Low carbohydrate - high fat diet;   Dietary Supplement: High carbohydrate - low fat diet
    Sponsor:   Vårdcentralen Lyckorna
    Active, not recruiting - verified October 2009
  • Comparison of NN1250 With Insulin Glargine in Type 2 Diabetes

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Drug: NN1250;   Drug: NN1250;   Drug: insulin glargine
    Sponsor:   Novo Nordisk
    Not yet recruiting - verified September 2009
  • Effects of Low Versus High Carbohydrate Diet During Rehabilitation on Cardiovascular Function and Metabolism in Type 2 Diabetes

    Conditions:   Type 2 Diabetes Mellitus;   Overweight
    Interventions:   Other: LOGI diet;   Other: Low Fat diet
    Sponsors:   Munich Municipal Hospital;   Stately Pension System (LVA) Baden-Wuertemberg;   Ueberruh Rehabilitation Clinic, Isny, Baden-Wuertemberg
    Active, not recruiting - verified October 2009
  • A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and and Pharmacodynamics of GSK1362885 in Type 2 Diabetics

    Condition:   Diabetes Mellitus, Type 2
    Interventions:   Drug: GSK1362885;   Drug: GSK1362885
    Sponsor:   GlaxoSmithKline
    Active, not recruiting - verified November 2009
  • Effectiveness Study of Community-Based, Peer-Led Education on Weight Loss and Diabetes

    Condition:   Pre-diabetes
    Intervention:   Behavioral: Project HEED (Help Educate to Eliminate Diabetes), a community-based, peer-led weight loss program for overweight adults with pre-diabetes.
    Sponsors:   Mount Sinai School of Medicine;   Union Memorial Hospital;   NORTH GENERAL HOSPITAL;   Albert Einstein College of Medicine of Yeshiva University
    Recruiting - verified October 2009
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