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Paid Clinical Trials - : Eye Diseases

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  • Safety & Efficacy Study of the IRay System in Patients With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)

    Conditions:   AMD;   Wet AMD;   Age-Related Macular Degeneration;   Wet Age-Related Macular Degeneration;   Macular Degeneration;   Eye Diseases;   Retinal Diseases
    Intervention:   Device: IRay
    Sponsor:   Oraya Therapeutics, Inc.
    Not yet recruiting - verified November 2009
  • A Four Week Study of Azithromycin Ophthalmic Solution, 1% Versus Placebo in Subjects With Dry Eye Disease

    Condition:   Dry Eye Disease
    Interventions:   Drug: Azithromycin Ophthalmic Solution, 1%;   Drug: Placebo
    Sponsor:   Inspire Pharmaceuticals
    Recruiting - verified November 2009
  • Aqueous Mushroom Extract and Intraocular Pressure

    Condition:   Glaucoma
    Interventions:   Drug: OME;   Drug: OME;   Drug: OME;   Drug: OME;   Drug: OME;   Drug: OME
    Sponsor:   University of Benin
    Not yet recruiting - verified November 2009
  • Safety and Efficacy of a Glaucoma Drug Delivery System

    Conditions:   Open-Angle Glaucoma;   Ocular Hypertension
    Interventions:   Drug: bimatoprost;   Drug: bimatoprost;   Drug: Placebo
    Sponsor:   Vistakon Pharmaceuticals
    Recruiting - verified November 2009
  • Clinical Evaluation of a Multifocal Contact Lens on Symptomatic Patients

    Condition:   Presbyopia
    Interventions:   Device: Etafilcon A Multifocal Contact Lens;   Device: Etafilcon A Contact Lens
    Sponsors:   Vistakon;   Visioncare Research Ltd.
    Recruiting - verified November 2009
  • Ranibizumab Therapy for Choroidal Neovascularization (CNV) Asociated With Angioid Streaks

    Condition:   Angioid Streaks
    Intervention:   Drug: ranibizumab
    Sponsors:   University of Illinois;   Genentech
    Not yet recruiting - verified November 2009
  • A Safety/Proof of Concept Study to Evaluate the Effects of Oral QLT091001 in Children With Leber Congenital Amaurosis (LCA)

    Condition:   Visual Impairment Due to Leber Congenital Amaurosis (LCA)
    Intervention:   Drug: QLT091001
    Sponsor:   QLT Inc
    Recruiting - verified November 2009
  • The Effect of a New Emulsion in Dry Eye Patients on Tear Layer Aberrometry, Contrast Sensitivity, and Reading Ability

    Condition:   Dry Eye Syndrome
    Interventions:   Drug: Optive;   Drug: Soothe;   Drug: New Emulsion
    Sponsors:   Southern California College of Optometry;   Allergan
    Recruiting - verified November 2009
  • A Multicenter Study to Evaluate Safety and Efficacy of Specific Immunotherapy With Modified Allergen Extracts

    Conditions:   Allergic Rhinitis;   Allergic Conjunctivitis
    Interventions:   Biological: modified allergen extract;   Biological: Placebo
    Sponsor:   Roxall Medizin
    Not yet recruiting - verified November 2009
  • Safety And Tolerability Study Of RN6G In Subjects With Advanced Dry, Age-Related Macular Degeneration Including Geographic Atrophy

    Conditions:   Age-Related Maculopathy;   Age-Related Maculopathies;   Eye Diseases;   Retinal Degeneration;   Macular Degeneration
    Interventions:   Biological: RN6G;   Biological: Placebo
    Sponsor:   Pfizer
    Not yet recruiting - verified November 2009
  • Impact of Lucentis on Psychological Morbidity in Patients With Retinal Vein Occlusion

    Conditions:   Branch Retinal Vein Occlusion;   Central Retinal Vein Occlusion;   Retinal Vein Occlusion;   Depression
    Intervention:   Drug: ranibizumab (Lucentis)
    Sponsors:   Retina Associates of Cleveland, Inc;   Genentech
    Recruiting - verified November 2009
  • Foresee Home for Monitoring Age Related Macular Degeneration (AMD)

    Condition:   Age Related Macular Degeneration
    Intervention:   Device: Foresee Home
    Sponsor:   Notal Vision Ltd
    Not yet recruiting - verified November 2009
  • Safety and Efficacy of Two Artificial Tears in Dry Eye Subjects

    Condition:   Dry Eye Syndrome
    Interventions:   Drug: Glycerin and Polysorbate 80 based artificial tear;   Drug: Formulation 1: Carboxymethylcellulose sodium, glycerin and Polysorbate 80, based artificial tear;   Drug: Formulation 2: Carboxymethylcellulose sodium, glycerin, and Polysorbate 80 based artificial tear
    Sponsor:   Allergan
    Not yet recruiting - verified November 2009
  • Efficacy and Safety of Belimumab in Primary Sjögren's Syndrome

    Condition:   Sjögren's Syndrome
    Intervention:   Drug: LimphoStat-B
    Sponsors:   University of Udine;   Azienda Ospedaliera S. Maria della Misericordia
    Recruiting - verified November 2009
  • The Safety and Efficacy of Lacrimal Silicone Intubation for the Management of Epiphora

    Condition:   Epiphora
    Intervention:   Device: Lacrimal Tube
    Sponsor:   Aurolab
    Not yet recruiting - verified November 2009
  • Macular EpiRetinal Brachytherapy Versus Lucentis® Only Treatment (MERLOT)

    Condition:   Macular Degeneration
    Interventions:   Device: Epimacular Brachytherapy;   Drug: Ranibizumab
    Sponsors:   King's College Hospital NHS Trust;   NeoVista
    Not yet recruiting - verified November 2009
  • Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Central Retinal Vein Occlusion (CRVO)

    Condition:   Retinal Vein Occlusion
    Interventions:   Drug: VEGF Trap-Eye (BAY86-5321);   Other: Sham treatment
    Sponsors:   Bayer;   Regeneron Pharmaceuticals
    Recruiting - verified November 2009
  • Temozolomide and Sunitinib Malate in Treating Patients With Stage III or Stage IV Malignant Melanoma

    Conditions:   Intraocular Melanoma;   Melanoma (Skin)
    Interventions:   Drug: sunitinib malate;   Drug: temozolomide
    Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
    Not yet recruiting - verified October 2009
  • Intraocular Pressure (IOP) Lowering Effect of Selective Laser Trabeculoplasty Versus Prostaglandin Analogues in Angle Closure Glaucoma

    Condition:   Glaucoma
    Interventions:   Procedure: Selective Laser Trabeculoplasty;   Drug: Travoprost/ Timolol/ Azopt/ Brimonidine
    Sponsor:   Singapore Eye Research Institute
    Recruiting - verified October 2009
  • Evaluation of Tranilast to Treat Pterygium Before Excision

    Condition:   Pterygium
    Interventions:   Drug: Tranilast, and Beriplast P;   Other: Beriplast P
    Sponsors:   Sao Jose do Rio Preto University;   Hospital de Base
    Recruiting - verified October 2009
  • Ranibizumab DosE Comparison and the Role of LAser in REtinal Vein Occlusions

    Condition:   Retinal Vein Occlusion
    Interventions:   Drug: Ranibizumab .5mg;   Drug: Ranibizumab .5mg with laser;   Drug: Ranibizumab 2.0 mg;   Drug: Ranibizumab 2.o dose with laser
    Sponsors:   Johns Hopkins University;   Genentech
    Not yet recruiting - verified October 2009
  • Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACU-4429 in Subjects With Geographic Atrophy

    Conditions:   Dry Age-related Macular Degeneration;   Geographic Atrophy
    Interventions:   Drug: ACU-4429;   Drug: Matching placebo
    Sponsors:   Acucela Inc.;   Otsuka Pharmaceutical Co., Ltd.
    Recruiting - verified October 2009
  • Safety and Efficacy Study in Subjects With Leber Congenital Amaurosis

    Condition:   Leber Congenital Amaurosis Due to RPE65 Mutations
    Intervention:   Biological: AAV2-hRPE65v2
    Sponsors:   Children's Hospital of Philadelphia;   University of Iowa
    Not yet recruiting - verified October 2009
  • A Comparison of Peak Aqueous Penetration and PEG2 Inhibition of Acuvail, Xibrom, and Nevanac in Patients Undergoing Phacoemulsification

    Condition:   Cataracts
    Interventions:   Drug: Ketorolac Tromethamine 0.45%;   Drug: bromfenac 0.09%;   Drug: nepafenac 0.1%
    Sponsors:   Bucci Laser Vision Institute;   Allergan
    Recruiting - verified October 2009
  • AL-38583 Ophthalmic Solution for Allergic Conjunctivitis Associated Inflammation

    Condition:   Allergic Conjunctivitis Associated Inflammation
    Interventions:   Drug: AL-38583 Ophthalmic Solution;   Drug: AL-38583 Ophthalmic Solution Vehicle;   Drug: Dexamethasone Ophthalmic Suspension
    Sponsors:   Alcon Research;   Ophthalmic Research Associates, Inc
    Not yet recruiting - verified October 2009
  • Safety and Efficacy of Three Formulations of AGN 210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution

    Condition:   Primary Open-Angle Glaucoma
    Interventions:   Drug: AGN-210669 0.05% ophthalmic solution;   Drug: AGN-210669 0.075% ophthalmic solution;   Drug: AGN-210669 0.1% ophthalmic solution;   Drug: bimatoprost 0.03% ophthalmic solution
    Sponsor:   Allergan
    Not yet recruiting - verified October 2009
  • Safety and Tolerability of Chitosan-N-acetylcysteine Eye Drops in Healthy Young Volunteers

    Condition:   Dry Eye Syndroms
    Intervention:   Device: Chitosan- N- Acetylcysteine eye drops
    Sponsor:   Medical University of Vienna
    Not yet recruiting - verified November 2009
  • Safety and Efficacy of AIN457 in Behçet's Patients With Posterior or Panuveitis

    Condition:   Behcet Disease
    Interventions:   Biological: AIN457;   Biological: AIN457;   Biological: Placebo
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified November 2009
  • Study on the Effect of Mitomycin C 0.02% on the Corneal Endothelial After Photorefractive Keratectomy in Moderate Myopia

    Condition:   Myopia
    Interventions:   Drug: Mitomycin C 0.02%;   Drug: Placebo
    Sponsor:   Shaheed Beheshti Medical University
    Recruiting - verified October 2009
  • Macular Pigment Optical Density in Healthy Subjects

    Condition:   Age Related Macular Degeneration
    Intervention:  
    Sponsor:   Medical University of Vienna
    Recruiting - verified November 2009
  • Genetic Analysis of PHACE Syndrome (Hemangioma With Other Congenital Anomalies)

    Condition:   PHACE Syndrome
    Intervention:  
    Sponsors:   Oregon Health and Science University;   Oregon Clinical and Translational Research Institute;   Society for Pediatric Dermatology
    Recruiting - verified November 2009
  • Panitumumab and Irinotecan for Malignant Gliomas

    Condition:   Recurrent Grade IV Malignant Glioma
    Intervention:   Drug: Panitumumab in Combination with Irinotecan
    Sponsors:   Duke University;   Amgen
    Not yet recruiting - verified November 2009
  • Internal Monitoring of Eye Movement in Schizophrenia

    Condition:   Schizophrenia
    Intervention:  
    Sponsor:   National Eye Institute (NEI)
    Recruiting - verified October 2009
  • Early Increase in Blood Flow (EIBS) in the Duodenum in Patients With Pancreatic Cancer

    Condition:   Pancreatic Cancer
    Interventions:   Procedure: Endoscopic Ultrasound (EUS);   Device: EUS/4D-ELF
    Sponsor:   Mayo Clinic
    Not yet recruiting - verified November 2009
  • Effect of Veramyst and Olopadatine 0.2% Opthalmic Solution on Allergy Symptoms

    Condition:   Seasonal Allergic Rhinitis
    Interventions:   Drug: Veramyst /Artificial tears;   Drug: Veramyst / Artificial tears lubricant eye drops;   Drug: Veramyst nasal spray and Olopatadine eye drops;   Other: Veramyst placebo and Olopatadine0.2% eye drops
    Sponsors:   University of Chicago;   GlaxoSmithKline
    Recruiting - verified November 2009
  • Idiopathic Intracranial Hypertension Treatment Trial

    Condition:   Idiopathic Intracranial Hypertension
    Interventions:   Drug: Acetazolamide;   Drug: Placebo;   Behavioral: Formal weight loss counselling program for both treatment groups
    Sponsors:   St. Luke's-Roosevelt Hospital Center;   National Eye Institute (NEI);   University of Rochester;   University of Iowa;   University of California, Davis
    Not yet recruiting - verified October 2009
  • Argon Laser Peripheral Iridoplasty for Primary Angle Closure Glaucoma :A Randomised Controlled Trial

    Condition:   Glaucoma
    Interventions:   Procedure: Argon Laser Iridoplasty;   Drug: Travatan/ Timolol/Azopt
    Sponsors:   Singapore National Eye Centre;   National University Hospital, Singapore
    Recruiting - verified November 2009
  • Bimatoprost Ophthalmic Solution in Promoting Eyebrow and Eyelash Hair Growth in Breast Cancer Patients After Chemotherapy or Healthy Participants

    Conditions:   Alopecia;   Breast Cancer
    Interventions:   Drug: bimatoprost ophthalmic solution;   Other: placebo
    Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
    Not yet recruiting - verified October 2009
  • Safety Study of Ragweed Allergy Immunotherapy Tablet in Subjects 50 Years of Age and Older (Study P06081)

    Conditions:   Rhinoconjunctivitis;   Rhinitis;   Conjunctivitis;   Allergy
    Interventions:   Biological: Placebo;   Biological: SCH 39641;   Biological: SCH 39641
    Sponsor:   Schering-Plough
    Not yet recruiting - verified November 2009
  • Study With High Dose PURETHAL Mites in Allergic Rhinitis/Rhinoconjunctivitis Patients

    Conditions:   Allergic Rhinitis;   Allergic Rhinoconjunctivitis
    Interventions:   Drug: PURETHAL Mites 20,000 AUeq/ml;   Drug: PURETHAL Mites 20,000 AUeq/ml;   Drug: PURETHAL Mites 20,000 AUeq/ml
    Sponsor:   HAL Allergy
    Recruiting - verified November 2009
  • Treatment of Iron Deficiency Anemia in Malaria Endemic Ghana

    Condition:   Anemia
    Interventions:   Dietary Supplement: Sprinkles®;   Dietary Supplement: vitamin/mineral fortificant without iron
    Sponsor:   The Hospital for Sick Children
    Not yet recruiting - verified October 2009
  • Time To Complications Occurs in Diabetes

    Conditions:   Retinopathy;   Nephropathy;   Diabetic Neuropathy;   Vascular Disease;   Ischemic Heart Disease
    Intervention:  
    Sponsor:   Karolinska Institutet
    Not yet recruiting - verified October 2009
  • Acupuncture for Dry Eye Syndrome

    Condition:   Dry Eye Syndromes
    Interventions:   Device: Standardized Acupuncture;   Device: Non-acupuncture point shallow penetration acupuncture
    Sponsor:   Korea Institute of Oriental Medicine
    Recruiting - verified October 2009
  • Clinical Trial for Non-responders Who Previously Participated in Eltrombopag Studies TPL 103922 or TPL 108390

    Conditions:   Hepatitis C;   Thrombocytopaenia
    Intervention:   Drug: Eltrombopag
    Sponsor:   GlaxoSmithKline
    Recruiting - verified November 2009
  • The Treatment of Uveitic Cystoid Macular Edema With Topical Interferon Gamma

    Condition:   Uveitis
    Intervention:   Drug: Interferon Gamma 1-b
    Sponsor:   National Eye Institute (NEI)
    Recruiting - verified July 2009
  • Prospective Health Assessment of Cataract Patients' Ocular Surface

    Condition:   Dry Eye
    Intervention:  
    Sponsor:   Innovative Medical
    Recruiting - verified November 2009
  • Intravitreal Diclofenac Versus Avastin as Primary Treatment of Diffuse Diabetic Macular Edema

    Condition:   Diffuse Diabetic Macular Edema
    Interventions:   Drug: Bevacizumab;   Drug: Diclofenac
    Sponsor:   Shaheed Beheshti Medical University
    Recruiting - verified October 2009
  • Evaluation of Omeprazole Effect on Glaucoma

    Condition:   Glaucoma
    Interventions:   Drug: Omeprazole;   Drug: Placebo
    Sponsors:   Shaheed Beheshti Medical University;   Ophthalmic Research Center
    Recruiting - verified October 2009
  • A Phase 2 Study Of The 24-Hour Intraocular Pressure Lowering And Systemic Exposure Of PF-04217329

    Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension
    Interventions:   Drug: PF-04217329;   Drug: PF-04217329 vehicle
    Sponsor:   Pfizer
    Not yet recruiting - verified October 2009
  • A Study to Evaluate New or Worsening Lens Opacifications in Subjects With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss Due to Androgen-Deprivation Therapy

    Conditions:   Cancer;   Cataract;   Low Bone Mineral Density;   Osteopenia;   Osteoporosis;   Prostate Cancer
    Interventions:   Biological: Denosumab;   Biological: Placebo
    Sponsor:   Amgen
    Not yet recruiting - verified November 2009
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