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Paid Clinical Trials - : Bone Disease

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  • OTIS Autoimmune Diseases in Pregnancy Project

    Conditions:   Ankylosing Spondylitis;   Psoriatic Arthritis;   Psoriasis;   Rheumatoid Arthritis
    Intervention:  
    Sponsors:   University of California, San Diego;   Organization of Teratology Information Specialists (OTIS);   Amgen
    Recruiting - verified November 2009
  • Short and Long Term Efficacy of Combined Cabergoline and Octreotide Treatment in Acromegalic Patients

    Condition:   Acromegaly
    Intervention:   Drug: cabergoline
    Sponsor:   Federal University of São Paulo
    Completed - verified November 2009
  • Efficacy of the Aspen Spinous Process System in Anterior Lumbar Interbody Fusion (ALIF)

    Condition:   Degenerative Disc Disease
    Interventions:   Device: Aspen Spinous Process System;   Device: Pedicle Screw Fixation
    Sponsor:   Lanx, Inc.
    Not yet recruiting - verified November 2009
  • Magnetic Resonance Imaging (MRI) Interpretations for Lumbar Spinal Stenosis (LSS)

    Condition:   Lumbar Spinal Stenosis
    Intervention:   Procedure: MRI
    Sponsor:   State University of New York - Upstate Medical University
    Recruiting - verified November 2009
  • Coventry Outcomes Study of Seniors (COSS): A Comparative Effectiveness Study to Evaluate the Effect of a Multidisciplinary Team's Intervention on the Incidence of Nonelective Hospitalizations in a Medicare Population

    Conditions:   Heart Failure;   Chronic Obstructive Pulmonary Disease;   Cardiovascular Disease;   Diabetes;   Osteoporosis
    Interventions:   Other: Multidisciplinary team interventions;   Other: Multidisciplinary team bimonthly visits either in person or via telephone.;   Other: Usual case management and pharmacy management as provided by the health Plan and the pharmacy benefit manager
    Sponsors:   Medco Health Solutions, Inc.;   Coventry Health Care, Inc.
    Enrolling by invitation - verified November 2009
  • Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease

    Conditions:   Coronary Artery Disease;   Chronic Kidney Disease;   Hypovitaminosis D;   Secondary Hyperparathyroidism
    Interventions:   Drug: paricalcitol;   Drug: placebo
    Sponsors:   Thomas Jefferson University;   Abbott
    Recruiting - verified November 2009
  • Efficacy of Gabapentin or Amitriptyline to Reduce Postoperative Pain After Lumbar Laminectomy and Diskectomy

    Conditions:   Herniated Disc;   Intervertebral Disc Displacement
    Intervention:   Drug: Gabapentin , Amitriptyline
    Sponsor:   Tabriz University
    Recruiting - verified November 2009
  • A Study for the Transdermal Application of Teriparatide

    Condition:   Osteoporosis
    Interventions:   Drug: Subcutaneous Teriparatide;   Drug: Transdermal Teriparatide
    Sponsors:   Eli Lilly and Company;   TransPharma Medical
    Not yet recruiting - verified November 2009
  • Actifuse ABX Versus INFUSE in Posterolateral Instrumented Lumbar Fusion (PLIF) With Interbody Fusion

    Condition:   Degenerative Disc Disease
    Interventions:   Procedure: Actifuse ABX;   Procedure: INFUSE, plus master granules (MGG)
    Sponsor:   Apatech, Inc.
    Recruiting - verified November 2009
  • Comparison of Cage Versus Plate in One Level Cervical Disc Disease

    Condition:   Cervical Disc Disease
    Intervention:  
    Sponsor:   Seoul National University Hospital
    Recruiting - verified November 2009
  • Treatment of Symptomatic Lumbar Internal Disc Disruption (IDD) With the Biostat® System

    Conditions:   Back Pain;   Chronic Low Back Pain;   Internal Disc Disruption;   Degenerative Disc Disease
    Interventions:   Biological: Biostat System;   Drug: Sodium Chloride Injection
    Sponsor:   Spinal Restoration, Inc.
    Not yet recruiting - verified November 2009
  • The Effect of Lanthanum Carbonate on Fibroblast Growth Factor 23 ( FGF23) in Chronic Kidney Disease

    Condition:   Metabolic Bone Disease
    Interventions:   Drug: Lanthanum Carbonate;   Drug: Fosrenol;   Drug: placebo
    Sponsors:   NorthShore University HealthSystem Research Institute;   Shire Pharmaceutical Development
    Not yet recruiting - verified October 2009
  • An Observational Study (Registry) Assessing Treatment Outcomes and Safety for Children and Adults Who Are Prescribed Norditropin (Human Growth Hormone)

    Conditions:   Dwarfism, Pituitary;   Hypopituitarism
    Intervention:   Drug: somatropin
    Sponsor:   Novo Nordisk
    Enrolling by invitation - verified November 2009
  • A Study on M2a Magnum Total Hip Arthroplasty

    Conditions:   Degenerative Joint Disease (Inflammatory or Non-inflammatory);   Osteoarthritis;   Avascular Necrosis
    Interventions:   Device: M2a Magnum;   Device: M2a Taper
    Sponsor:   Biomet, Inc.
    Not yet recruiting - verified November 2009
  • A Study of the Safety and Efficacy of Ustekinumab in Patients With Psoriatic Arthritis

    Condition:   Arthritis, Psoriatic
    Interventions:   Drug: placebo;   Drug: ustekinumab;   Drug: ustekinumab;   Drug: ustekinumab;   Drug: ustekinumab;   Drug: ustekinumab;   Drug: placebo;   Drug: placebo
    Sponsor:   Centocor, Inc.
    Not yet recruiting - verified November 2009
  • Comparison of Allogenix Plus Demineralized Bone Matrix and Autogenous Bone Dust Versus Autogenous Bone Dust Alone in Ossification of Small Calvarial Defects, a Pilot Study.

    Condition:   Metopic Craniosynostosis
    Intervention:   Biological: Allogenix Plus
    Sponsors:   University of Missouri-Columbia;   Biomet, Inc.
    Recruiting - verified October 2009
  • Fructooligosaccharide and Calcium Absorption in Adolescent Girls

    Condition:   Osteoporosis
    Intervention:   Dietary Supplement: Fructooligosaccharide
    Sponsors:   Purdue University;   Abbott Nutrition;   GTC Nutrition
    Recruiting - verified October 2009
  • Effect of Calcium Supplement Particle Size and Vitamin D Supplement on Calcium Retention in Adolescent Girls

    Condition:   Osteoporosis
    Interventions:   Dietary Supplement: Small Particle Size Calcium Carbonate Supplement;   Dietary Supplement: Large Particle Size Calcium Carbonate Supplement;   Dietary Supplement: Vitamin D;   Dietary Supplement: Calcium Placebo
    Sponsor:   Purdue University
    Completed - verified October 2009
  • Vaccination Against Influenza H1N1 in Rheumatic Diseases

    Conditions:   Influenza;   Rheumatic Diseases
    Interventions:   Biological: Focetria (Monovalent MF59-Adjuvanted vaccine);   Biological: Focetria (Monovalent MF59-Adjuvanted vaccine);   Biological: Focetria (Monovalent MF59-Adjuvanted vaccine)
    Sponsor:   Tel-Aviv Sourasky Medical Center
    Not yet recruiting - verified November 2009
  • Consistency & Immunogenicity Study of 3 Lots of GSK's Hib Conjugate Vaccine Versus ActHIB & Pentacel in Healthy Infants

    Conditions:   Haemophilus Influenzae Type B Related Disease;   Pneumonia;   Meningitis;   Cellulitis;   Osteomyelitis;   Epiglottis
    Interventions:   Biological: GSK Biologicals' Haemophilus inluenzae type b vaccine (GSK 208108);   Biological: ActHIBTM;   Biological: PentacelTM;   Biological: PediarixTM;   Biological: PrevnarTM;   Biological: RotarixTM;   Biological: EngerixTM-B;   Biological: InfanrixTM
    Sponsor:   GlaxoSmithKline
    Not yet recruiting - verified November 2009
  • Surgical Versus Medical Treatment of Acromegaly

    Condition:   Acromegaly
    Intervention:  
    Sponsor:   University of Aarhus
    Active, not recruiting - verified October 2009
  • Allogenic Bone Marrow Transplantation (BMT) Compare With Cytoreduction and Chemotherapy in Acute Lymphoblastic Leukemia (ALL) Patients

    Condition:   Acute Lymphoblastic Leukemia
    Interventions:   Procedure: Bone Marrow Transplantation;   Procedure: Chemotherapy
    Sponsors:   Tehran University of Medical Sciences;   Hematology-Oncology and Stem Cell Transplantation Research Center
    Recruiting - verified November 2009
  • Safety and Tolerability Trial of Abatacept-based Immunosuppression for Prevention of Acute Graft Versus Host Disease (aGVHD) During Transplant

    Conditions:   AML;   ALL;   Undifferentiated Leukemia;   Biphenotypic Leukemia;   Refractory Anemia;   Refractory Anemia With Ringed Sideroblasts;   Refractory Cytopenia With Multilineage Dysplasia;   Refractory Cytopenia With Multilineage Dysplasia and Ringed Sideroblasts;   Refractory Anemia With Excess Blasts-1 (5-10% Blasts);   Refractory Anemia With Excess Blasts-2 (10-20% Blasts);   Myelodysplastic Syndrome, Unclassified;   MDS Associated With Isolated Del (5q)
    Intervention:   Drug: Abatacept
    Sponsor:   Emory University
    Recruiting - verified November 2009
  • The Effect of Adalimumab on the Bone Microstructure in Crohn's Disease (CD) Patients

    Condition:   Crohn's Disease
    Intervention:   Drug: Application of Adalimumab
    Sponsor:   University of Zurich
    Recruiting - verified November 2009
  • Influence of Vitamin D Treatment on Multi-systemic Functions in Young Men With Vitamin D Deficiency Due to Work Conditions

    Condition:   Vitamin D Deficiency
    Interventions:   Dietary Supplement: Vitamin D;   Dietary Supplement: Placebo
    Sponsors:   Rambam Health Care Campus;   Ministry of Labour and Social Affairs, Israel
    Recruiting - verified November 2009
  • Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma

    Conditions:   Adult Malignant Fibrous Histiocytoma of Bone;   Ovarian Cancer;   Sarcoma
    Interventions:   Biological: cixutumumab;   Drug: temsirolimus;   Other: laboratory biomarker analysis
    Sponsors:   Memorial Sloan-Kettering Cancer Center;   National Cancer Institute (NCI)
    Not yet recruiting - verified November 2009
  • Prevention Chemotherapy Induced Mucositis by Zinc Sulfate

    Conditions:   Mucositis;   Bone Marrow Transplantation
    Interventions:   Drug: Zinc Sulfate;   Drug: Placebo
    Sponsors:   Tehran University of Medical Sciences;   Hematology-Oncology and Stem Cell Transplantation Research Center
    Recruiting - verified November 2009
  • Studying DNA in Blood and Bone Marrow Samples From Young Patients With Acute Lymphoblastic Leukemia

    Condition:   Leukemia
    Interventions:   Genetic: DNA analysis;   Other: biologic sample preservation procedure;   Other: laboratory biomarker analysis
    Sponsors:   Children's Oncology Group;   National Cancer Institute (NCI)
    Active, not recruiting - verified November 2009
  • Zoledronic Acid for the Prevention of Bone Loss Post-bone Marrow Transplantation for Thalassemia Major Patients

    Conditions:   Beta-Thalassemia;   Bone Marrow Transplantation
    Interventions:   Drug: Zoledronic acid;   Drug: Placebo
    Sponsors:   Tehran University of Medical Sciences;   Novartis;   Hematology-Oncology and Stem Cell Transplantation Research Center
    Recruiting - verified November 2009
  • Evaluation of Influenza H1N1 Vaccine in Adults With Lymphoid Malignancies on Chemotherapy

    Conditions:   Lymphoma;   Multiple Myeloma;   Influenza A Virus, H1N1 Subtype
    Intervention:   Biological: AS03-adjuvanted H1N1 pandemic influenza vaccine
    Sponsors:   University Health Network, Toronto;   Princess Margaret Hospital, Canada
    Recruiting - verified November 2009
  • Peripheral Blood Stem Cell Transplant in Treating Patients With High-Risk Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia

    Conditions:   Hematopoietic/Lymphoid Cancer;   Adult Nasal Type Extranodal NK/T-cell Lymphoma;   Anaplastic Large-Cell Lymphoma;   Angioimmunoblastic T-cell Lymphoma;   B-cell Chronic Lymphocytic Leukemia;   Burkitt Lymphoma;   Childhood Diffuse Large Cell Lymphoma;   Childhood Immunoblastic Large Cell Lymphoma;   Childhood Nasal Type Extranodal NK/T-cell Lymphoma;   Cutaneous B-cell Non-Hodgkin Lymphoma;   Lymphoma, Mucosa-Associated Lymphoid Tissue;   Intraocular Lymphoma;   Nodal Marginal Zone B-cell Lymphoma;   Peripheral T-Cell Lymphoma;   Prolymphocytic Leukemia;   Recurrent Adult Burkitt Lymphoma;   Recurrent Adult Diffuse Large Cell Lymphoma;   Recurrent Adult Diffuse Mixed Cell Lymphoma;   Recurrent Adult Diffuse Small Cleaved Cell Lymphoma;   Recurrent Adult Grade III Lymphomatoid Granulomatosis;   Recurrent Adult Hodgkin Lymphoma;   Recurrent Adult Immunoblastic Large Cell Lymphoma;   Recurrent Adult Lymphoblastic Lymphoma;   Recurrent Childhood Anaplastic Large Cell Lymphoma;   Recurrent Childhood Grade III Lymphomatoid Granulomatosis;   Recurrent Childhood Large Cell Lymphoma;   Recurrent Childhood Lymphoblastic Lymphoma;   Recurrent Childhood Small Noncleaved Cell Lymphoma;   Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma;   Recurrent Grade 1 Follicular Lymphoma;   Recurrent Grade 2 Follicular Lymphoma;   Recurrent Grade 3 Follicular Lymphoma;   Recurrent Mantle Cell Lymphoma;   Recurrent Marginal Zone Lymphoma;   Recurrent Mycosis Fungoides/Sezary Syndrome;   Recurrent Small Lymphocytic Lymphoma;   Recurrent/Refractory Childhood Hodgkin Lymphoma;   Refractory Chronic Lymphocytic Leukemia;   Refractory Multiple Myeloma;   Splenic Marginal Zone Lymphoma;   Waldenstrom Macroglobulinemia
    Interventions:   Drug: carmustine;   Drug: etoposide;   Drug: cytarabine;   Drug: fludarabine phosphate;   Drug: cyclophosphamide;   Drug: tacrolimus;   Drug: mycophenolate mofetil;   Radiation: total-body irradiation;   Drug: melphalan;   Procedure: autologous-allogeneic tandem hematopoietic stem cell transplantation;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: allogeneic bone marrow transplantation;   Other: fluorescence in situ hybridization;   Other: flow cytometry;   Other: RNA analysis;   Other: laboratory biomarker analysis;   Other: cytogenetic analysis;   Other: polymerase chain reaction
    Sponsor:   Fred Hutchinson Cancer Research Center
    Not yet recruiting - verified November 2009
  • Human Tumor Necrosis Factor Alpha (TNFa)-Induced Pre-B Cell Bone Marrow Emigrants

    Condition:   Rheumatoid Arthritis
    Intervention:   Drug: Etanercept
    Sponsors:   University of Pittsburgh;   Amgen
    Recruiting - verified November 2009
  • Study on Duration of Bone Turnover Suppression Following Zoledronic Acid in Prostate Cancer

    Condition:   Prostate Cancer
    Intervention:  
    Sponsors:   University Health Network, Toronto;   Princess Margaret Hospital, Canada
    Not yet recruiting - verified November 2009
  • Intramedullary Fixation of Humerus Fractures

    Conditions:   Humeral Fractures;   Pathological Fractures
    Intervention:   Device: Quantum
    Sponsor:   N.M.B. Medical Applications Ltd
    Not yet recruiting - verified November 2009
  • Unrelated Double Umbilical Cord Blood Units Transplantation

    Conditions:   Leukemia, Myeloid, Acute;   Leukemia, Lymphoblastic, Acute;   Leukemia, Myeloid, Chronic
    Intervention:   Drug: Stem cell Transplantation
    Sponsors:   Tehran University of Medical Sciences;   Hematology-Oncology and Stem Cell Transplantation Research Center
    Recruiting - verified November 2009
  • IV Busulfan for Transplant in Multiple Myeloma

    Condition:   Multiple Myeloma
    Intervention:   Drug: IV busulfan and bortezomib combination
    Sponsor:   Otsuka Pharmaceutical Development & Commercialization, Inc.
    Not yet recruiting - verified November 2009
  • Azacitidine Combined to Epoetin Beta in International Prognostic Scoring System (IPSS) Low-risk and Intermediate-1 Myelodysplastic Syndrome (MDS) Patients, Resistant to Erythropoetin-stimulating Agents (ESA)

    Condition:   Myelodysplastic Syndromes
    Interventions:   Drug: Azacitidine;   Drug: Epoetin beta
    Sponsors:   Groupe Francophone des Myelodysplasies;   Celgene Corporation;   Roche Pharma AG
    Recruiting - verified November 2009
  • Prospective Multicentric Study of Cytomegalovirus Resistance in Transplant Patients and Bone Marrow Recipients

    Condition:   Cytomegalovirus
    Intervention:   Biological: depistage
    Sponsor:   University Hospital, Limoges
    Recruiting - verified November 2009
  • Prevention of Micro-architectural Bone Decay in Males With Non-metastatic Prostate Cancer Receiving Androgen Deprivation Therapy (ADT)

    Condition:   Prostate Cancer
    Interventions:   Drug: Zoledronic acid;   Drug: Placebo
    Sponsor:   Austin Health
    Not yet recruiting - verified November 2009
  • Nicotinamide Versus Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients

    Conditions:   Chronic Renal Failure;   Hemodialysis
    Interventions:   Drug: nicotinamide;   Drug: sevelamer;   Drug: cinacalcet
    Sponsor:   Centre Hospitalier Universitaire, Amiens
    Not yet recruiting - verified November 2009
  • Screening Tools to Predict Treatment Outcome in Older Cancer Patients Who Are Undergoing Treatment

    Conditions:   Chronic Myeloproliferative Disorders;   Leukemia;   Lymphoma;   Lymphoproliferative Disorder;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases;   Unspecified Adult Solid Tumor, Protocol Specific
    Interventions:   Drug: chemotherapy;   Other: questionnaire administration;   Procedure: cognitive assessment;   Procedure: examination;   Procedure: management of therapy complications
    Sponsor:   Ziekenhuis Netwerk Antwerpen Middelheim
    Recruiting - verified October 2009
  • Tetradecanoylphorbol Acetate, Dexamethasone, and Choline Magnesium Trisalicylate in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    Condition:   Leukemia
    Interventions:   Drug: choline magnesium trisalicylate;   Drug: dexamethasone;   Drug: tetradecanoylphorbol acetate;   Other: laboratory biomarker analysis
    Sponsors:   Cancer Institute of New Jersey;   National Cancer Institute (NCI)
    Recruiting - verified October 2009
  • A Study to Assess the Safety of Using Fibroblast Growth Factor-2 With Periodontal Surgery in Japan (Phase 3)

    Condition:   Periodontitis
    Intervention:   Drug: Trafermin
    Sponsor:   Kaken Pharmaceutical
    Not yet recruiting - verified November 2009
  • Study of Blood and Bone Marrow Samples in Patients With Chronic Myelogenous Leukemia Enrolled on a CALGB Clinical Trial

    Condition:   Leukemia
    Interventions:   Genetic: DNA analysis;   Genetic: Southern blotting;   Genetic: cytogenetic analysis;   Genetic: polymerase chain reaction
    Sponsors:   Cancer and Leukemia Group B;   National Cancer Institute (NCI)
    Recruiting - verified November 2009
  • Safety Study of a Chemokine Receptor (CXCR4) Antagonist in Multiple Myeloma Patients

    Condition:   Multiple Myeloma
    Intervention:   Drug: BKT140
    Sponsor:   Biokine Therapeutics Ltd
    Recruiting - verified November 2009
  • Safety and Efficacy Study of AS101 to Treat Elderly Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Patients

    Conditions:   Acute Myeloid Leukemia;   Myelodysplastic Syndrome
    Intervention:   Drug: AS101
    Sponsor:   BioMAS Ltd
    Not yet recruiting - verified November 2009
  • Study of Oral Arsenic Trioxide With or Without Ascorbic Acid in Adults With Myelofibrosis

    Condition:   Primary Myelofibrosis
    Intervention:   Drug: Dose Escalating Arsenic Trioxide plus ascorbic Acid
    Sponsors:   Roswell Park Cancer Institute;   Cephalon
    Not yet recruiting - verified November 2009
  • Surgical Versus Conservative Treatment of Acute Mallet Fingers; a Randomised Controlled Trial

    Condition:   Finger Injury
    Intervention:   Procedure: extensor tendon repair
    Sponsor:   Mid Cheshire Hospitals NHS Foundation Trust
    Not yet recruiting - verified November 2009
  • Use of Tendon Vibration and Mirror for the Improvement of Upper Limb Function and Pain Reduction

    Conditions:   Stroke;   Hemiplegia
    Interventions:   Device: Vibration and Mirror;   Device: Mirror therapy;   Device: no mirror, sham vibration
    Sponsor:   Hadassah Medical Organization
    Not yet recruiting - verified November 2009
  • Pentostatin, Cyclophosphamide Plus Rituximab (PCR) for the Therapy of Poor-Prognosis Chronic Graft-Versus-Host Disease

    Condition:   Active Chronic Graft Versus Host Disease
    Intervention:   Drug: Pentostatin; Cyclophosphamide; Rituximab
    Sponsor:   University of Rochester
    Recruiting - verified October 2009
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