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Paid Clinical Trials - : Autoimmune Diseases

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  • OTIS Autoimmune Diseases in Pregnancy Project

    Conditions:   Ankylosing Spondylitis;   Psoriatic Arthritis;   Psoriasis;   Rheumatoid Arthritis
    Intervention:  
    Sponsors:   University of California, San Diego;   Organization of Teratology Information Specialists (OTIS);   Amgen
    Recruiting - verified November 2009
  • Influence of Vitamin D Treatment on Multi-systemic Functions in Young Men With Vitamin D Deficiency Due to Work Conditions

    Condition:   Vitamin D Deficiency
    Interventions:   Dietary Supplement: Vitamin D;   Dietary Supplement: Placebo
    Sponsors:   Rambam Health Care Campus;   Ministry of Labour and Social Affairs, Israel
    Recruiting - verified November 2009
  • Real-Time Continuous Glucose Monitoring in Pre-School Children With Type-1 Diabetes Mellitus

    Condition:   Diabetes Mellitus
    Intervention:   Device: Guardian RT
    Sponsor:   Sheba Medical Center
    Recruiting - verified November 2009
  • The Efficacy of Enteric-coated Mycophenolate Sodium (EC-MPS) (Myfortic) in The Treatment of Relapse or Resistant Proliferative Lupus Nephritis

    Condition:   Lupus Nephritis
    Interventions:   Drug: mycophenolate sodium;   Drug: cyclophosphamide
    Sponsors:   Chulalongkorn University;   Clinical Research Collaborative Network;   Health Intervention and Technology Assessment Program (HITAP)
    Not yet recruiting - verified November 2009
  • Prospective Observational Long-term Safety Registry of Multiple Sclerosis Patients Who Have Participated in Cladribine Clinical Trials

    Condition:   Multiple Sclerosis
    Intervention:  
    Sponsor:   EMD Serono
    Recruiting - verified November 2009
  • Efficacy and Safety of Belimumab in Primary Sjögren's Syndrome

    Condition:   Sjögren's Syndrome
    Intervention:   Drug: LimphoStat-B
    Sponsors:   University of Udine;   Azienda Ospedaliera S. Maria della Misericordia
    Recruiting - verified November 2009
  • Golimumab in Rheumatoid Arthritis Patients With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)

    Conditions:   Arthritis;   Arthritis, Rheumatoid;   Autoimmune Diseases
    Interventions:   Drug: golimumab;   Drug: golimumab or placebo;   Drug: golimumab or placebo
    Sponsors:   Centocor, Inc.;   Schering-Plough
    Recruiting - verified November 2009
  • SC12267 (4SC-101) in Combination With Methotrexate in Patients With Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: SC12267 (4SC-101);   Drug: Placebo;   Drug: Methotrexate;   Drug: Folic Acid
    Sponsor:   4SC AG
    Recruiting - verified November 2009
  • Subcutaneous Immunoglobulin Treatment of Patients With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

    Condition:   Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
    Intervention:   Drug: Subcutaneous immunoglobulin
    Sponsors:   University of Aarhus;   Baxter Healthcare Corporation;   GCP-unit at Aarhus University Hospital, Aarhus, Denmark
    Not yet recruiting - verified November 2009
  • Human Tumor Necrosis Factor Alpha (TNFa)-Induced Pre-B Cell Bone Marrow Emigrants

    Condition:   Rheumatoid Arthritis
    Intervention:   Drug: Etanercept
    Sponsors:   University of Pittsburgh;   Amgen
    Recruiting - verified November 2009
  • Study Evaluating the Efficacy and Safety of SBI-087 in Seropositive Subjects With Active Rheumatoid Arthritis

    Condition:   Active Rheumatoid Arthritis
    Intervention:   Drug: SBI-087
    Sponsor:   Wyeth
    Recruiting - verified November 2009
  • A Pharmacokinetic/Pharmacodynamic Study of Intravenous and Subcutaneous CDP6038 in Subjects With Rheumatoid Arthritis on Methotrexate

    Conditions:   Arthritis;   Rheumatoid Arthritis
    Interventions:   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Biological: CDP6038;   Other: Placebo IV;   Other: Placebo SC
    Sponsor:   UCB, Inc.
    Recruiting - verified November 2009
  • A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: tocilizumab;   Drug: methotrexate
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009
  • Study Evaluating Multiple Ascending Doses of ATN-103 in Japanese Subjects With Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Biological: ATN-103 10 mg q4wks;   Biological: ATN-103 30 mg q4wks;   Biological: ATN-103 80 mg q4wks;   Biological: ATN-103 10 mg q8wks;   Biological: ATN-103 80 mg q8wks
    Sponsor:   Wyeth
    Recruiting - verified November 2009
  • ACT-128800 in Relapsing-remitting Multiple Sclerosis

    Condition:   Relapsing-Remitting Multiple Sclerosis
    Interventions:   Drug: ACT-128800;   Drug: Placebo
    Sponsor:   Actelion
    Recruiting - verified October 2009
  • Brain Computer Interface for Communication in ICU: a Feasibility Study

    Conditions:   Tetraplegia;   Guillain-Barre Syndrome
    Intervention:  
    Sponsor:   University of Versailles
    Not yet recruiting - verified October 2009
  • The Effects of Interferon Beta Combined With Vitamin D on Relapsing Remitting Multiple Sclerosis Patients

    Condition:   Multiple Sclerosis
    Interventions:   Dietary Supplement: Vitamin D3;   Dietary Supplement: Vitamin D3
    Sponsors:   Carmel Medical Center;   Merck Serono International SA
    Not yet recruiting - verified November 2009
  • Vaccination Against Influenza H1N1 in Rheumatic Diseases

    Conditions:   Influenza;   Rheumatic Diseases
    Interventions:   Biological: Focetria (Monovalent MF59-Adjuvanted vaccine);   Biological: Focetria (Monovalent MF59-Adjuvanted vaccine);   Biological: Focetria (Monovalent MF59-Adjuvanted vaccine)
    Sponsor:   Tel-Aviv Sourasky Medical Center
    Not yet recruiting - verified November 2009
  • Efficacy and Safety of Tocilizumab in Adult's Still Disease

    Condition:   Adult's Still Disease
    Intervention:   Drug: Tocilizumab
    Sponsors:   Tel-Aviv Sourasky Medical Center;   Rambam Health Care Campus;   Assaf-Harofeh Medical Center;   Bnai Zion Medical Center
    Not yet recruiting - verified September 2009
  • Efficacy, Pharmacokinetics, Safety and Immunogenicity Study of Abatacept Administered Subcutaneously to Treat Rheumatoid Arthritis in Japan

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: Abatacept;   Drug: Abatacept;   Drug: Abatacept;   Drug: Placebo
    Sponsor:   Bristol-Myers Squibb
    Not yet recruiting - verified November 2009
  • Comparison of Hypoglycaemic Response Between NN1250 and Insulin Glargine in Type 1 Diabetics

    Condition:   Diabetes Mellitus, Type 1
    Interventions:   Drug: NN1250;   Drug: insulin glargine
    Sponsor:   Novo Nordisk
    Recruiting - verified November 2009
  • Vanguard Complete Knee Versus Vanguard High Flex Rotating Platform (RP) Knee Study

    Conditions:   Osteoarthritis;   Rheumatoid Arthritis;   Traumatic Arthritis
    Interventions:   Device: Vanguard Complete Knee System w/ std tray;   Device: Vanguard High Flex RP
    Sponsor:   Biomet, Inc.
    Recruiting - verified November 2009
  • The Comparison Study of Intralesional Botulinum Toxin A and Corticosteroid Injection for Alopecia Areata

    Condition:   Alopecia Areata
    Interventions:   Drug: Botulinum toxin type A;   Drug: Triamcinolone acetonide
    Sponsor:   Siriraj Hospital
    Not yet recruiting - verified October 2009
  • Health Outcomes in Rheumatoid Arthritis in Greece

    Condition:   Rheumatoid Arthritis
    Intervention:  
    Sponsor:   Wyeth
    Not yet recruiting - verified October 2009
  • Rotation or Change of Biotherapy After First Anti-TNF Treatment Failure for Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: infliximab, etanercept, adalimumab;   Drug: abatacept, rituximab or tocilizumab
    Sponsor:   University Hospital, Strasbourg, France
    Not yet recruiting - verified October 2009
  • A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: rituximab [MabThera/Rituxan];   Drug: methotrexate;   Drug: methylprednisolone
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009
  • Cultivating Healthy Environments in Families With Type 1 Diabetes (CHEF)

    Condition:   Type I Diabetes
    Interventions:   Behavioral: Education;   Device: CGM;   Behavioral: Problem Solving;   Behavioral: Social Learning;   Behavioral: Behavior Modification
    Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Recruiting - verified August 2009
  • Study of the Effects of XOMA 052 on Insulin Production in Subjects With Well Controlled Type 1 Diabetes

    Condition:   Diabetes Mellitus, Type 1
    Intervention:   Drug: Xoma 052
    Sponsors:   University of Zurich;   Prof. M. Donath;   Juvenile Diabetes Research Foundation;   XOMA (US) LLC
    Not yet recruiting - verified October 2009
  • A Study of Tocilizumab Added to DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis and an Inadequate Response to DMARDs.

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: DMARDs (disease-modifying antirheumatic drugs)
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009
  • Cell Immunity Response to Vaccination Against Influenza in Patients With Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Intervention:   Biological: Agrippal S1 (Influenza vaccination)
    Sponsor:   Tel-Aviv Sourasky Medical Center
    Recruiting - verified October 2009
  • A Study of Tocilizumab in Combination With DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis With an Inadequate Response to DMARDs

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: DMARDs
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009
  • Tolerability, Safety, and Efficacy Study of INGAP Peptide to Treat Type 1 Diabetes Mellitus in Adults

    Condition:   Type 1 Diabetes Mellitus
    Interventions:   Drug: INGAP Peptide;   Drug: INGAP Peptide;   Drug: Placebo
    Sponsor:   Exsulin Corporation
    Recruiting - verified November 2009
  • Trichuris Suis Ova Therapy for Relapsing Multiple Sclerosis - a Safety Study

    Condition:   Relapsing Multiple Sclerosis
    Intervention:   Biological: Trichuris suis ova
    Sponsors:   Rigshospitalet, Denmark;   Faculty of LIFE Sciences, University of Copenhagen;   Statens Serum Institut;   Danish Research Centre for Magnetic Resonance,Copenhagen University Hospital;   Ovamed GmbH
    Not yet recruiting - verified November 2009
  • A Study of CDP870 as Add-on Meditation to Methotrexate (MTX) in Patients With Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: Placebo of CDP870;   Drug: CDP870 200mg
    Sponsor:   Korea Otsuka Pharmaceutical Co.,Ltd.
    Recruiting - verified October 2009
  • 6-month Comparison of Morning Lantus Versus Neutral Protamine Hagedorn Insulin in Young Children With Type 1 Diabetes

    Condition:   Type 1 Diabetes Mellitus
    Interventions:   Drug: INSULIN GLARGINE (HOE901);   Drug: Neutral Protamine Hagedorn (NPH) insulin
    Sponsor:   Sanofi-Aventis
    Recruiting - verified November 2009
  • The Use of Certolizumab Pegol in Adult Subjects With Rheumatoid Arthritis to Assess the Antibody Response When Receiving Influenza Virus and Pneumococcal Vaccines

    Condition:   Rheumatoid Arthritis
    Interventions:   Biological: Placebo;   Biological: Certolizumab pegol
    Sponsor:   UCB, Inc.
    Recruiting - verified November 2009
  • A Study of Tocilizumab in Patients With Active Polyarticular-Course Juvenile Idiopathic Arthritis

    Condition:   Juvenile Idiopathic Arthritis
    Interventions:   Drug: tocilizumab;   Drug: tocilizumab;   Drug: tocilizumab;   Drug: placebo;   Drug: NSAIDs, corticosteroids, methotrexate
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009
  • A Study on the Effect of 2 Pen Devices on HbA1c

    Condition:   Diabetes Mellitus, Type 1
    Interventions:   Drug: Insulin Lispro;   Drug: Huminsulin Regular;   Device: Huma Pen Memoir;   Device: Huma Pen Luxura
    Sponsor:   Eli Lilly and Company
    Recruiting - verified November 2009
  • A Study To Evaluate The Mechanism Of Action Of CP-690,550 In Patients With Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: CP-690,550 + methotrexate;   Drug: Placebo + Methotrexate
    Sponsor:   Pfizer
    Not yet recruiting - verified November 2009
  • An Efficacy and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis (RA) Despite Treatment With Methotrexate, Non Steroidal Pain Medications and/or Corticosteroids

    Condition:   Arthritis, Rheumatoid
    Interventions:   Biological: golimumab;   Biological: golimumab;   Biological: golimumab;   Drug: placebo
    Sponsors:   Centocor, Inc.;   Schering-Plough
    Recruiting - verified November 2009
  • Efficacy of Oncoxin Plus Viusid in the Treatment of Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Dietary Supplement: Oncoxin + Viusid;   Dietary Supplement: Placebo
    Sponsor:   Catalysis SL
    Recruiting - verified November 2009
  • A Study in Patients With Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Biological: LY2439821;   Drug: Placebo
    Sponsor:   Eli Lilly and Company
    Recruiting - verified November 2009
  • A Study to Evaluate the Efficacy and Safety of Rontalizumab in Patients With Moderately to Severely Active Systemic Lupus Erythematosus

    Condition:   Systemic Lupus Erythematosus
    Interventions:   Drug: placebo;   Drug: rontalizumab
    Sponsor:   Genentech
    Recruiting - verified November 2009
  • TORPEDO Study: A Study on Rapid Effect of Tocilizumab in Patients With Rheumatoid Arthritis With an Inadequate Response to Disease-Modifying Antirheumatic Drugs (DMARDs) or Anti-TNF

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: placebo;   Drug: tocilizumab
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009
  • A Study of Subcutaneously Administered Tocilizumab in Patients With Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: tocilizumab;   Drug: methotrexate;   Drug: folic acid
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009
  • Study of CP-690,550 Versus Placebo In Rheumatoid Arthritis Patients On Background Methotrexate With Inadequate Response To Tumor Necrosis Factor (TNF) Inhibitors

    Condition:   Arthritis, Rheumatoid
    Interventions:   Drug: CP-690,550;   Drug: CP-690,550;   Drug: Placebo;   Drug: CP-690,550;   Drug: Placebo;   Drug: CP-690,550
    Sponsor:   Pfizer
    Recruiting - verified November 2009
  • Study Evaluating Etanercept in 3 Subtypes of Childhood Arthritis

    Condition:   Arthritis, Juvenile Idiopathic
    Intervention:   Drug: Etanercept 0.8 mg/kg QW up to a maximum dose of 50 mg
    Sponsor:   Wyeth
    Recruiting - verified November 2009
  • AMG 827 in Rheumatoid Arthritis Subjects With Inadequate Response to Methotrexate

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: AMG 827 140 mg;   Drug: AMG 827 210 mg;   Drug: Placebo;   Drug: AMG 827 70 mg
    Sponsor:   Amgen
    Not yet recruiting - verified November 2009
  • Double Blind Placebo-Controlled Phase I/II Clinical Trial of Idebenone in Patients With Primary Progressive Multiple Sclerosis (IPPoMS)

    Condition:   Primary Progressive Multiple Sclerosis
    Intervention:   Drug: Idebenone
    Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
    Recruiting - verified July 2009
  • A Study of Tocilizumab + DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis

    Condition:   Rheumatoid Arthritis
    Interventions:   Drug: tocilizumab;   Drug: Standard DMARDs (Disease Modifying Anti Rheumatic Drugs)
    Sponsor:   Hoffmann-La Roche
    Recruiting - verified November 2009
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