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  • Everolimus in de Novo Heart Transplant Recipients

    Condition:   Cardiac Transplantation
    Interventions:   Drug: Everolimus;   Drug: Mycophenolate mofetil + Everolimus
    Sponsor:   Novartis
    Recruiting - verified November 2009
  • Efficacy, Safety, Tolerability and Pharmacokinetics of Indacaterol Maleate Via Concept1 or Simoon Devices

    Condition:   Asthma
    Interventions:   Drug: QAB149 placebo;   Drug: QAB149;   Drug: QAB149;   Drug: QAB149
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified November 2009
  • Safety, Efficacy and Immunogenicity Study of Fluad Versus Control Vaccines in Unprimed Healthy Children (6 to < 72 Months)

    Condition:   Influenza Disease
    Intervention:   Biological: Influenza virus vaccine: Influenza virus strains A/H1N1, A/H3N2, B
    Sponsors:   Novartis;   Novartis Vaccines
    Recruiting - verified November 2009
  • Effect of Indacaterol on Inspiratory Capacity (IC)

    Condition:   Chronic Obstructive Pulmonary Disease
    Interventions:   Drug: Indacaterol;   Drug: Tiotropium;   Drug: Placebo
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified November 2009
  • H1N1v Vaccination of Pregnant Women: A Longitudinal Cohort Study Characterizing Influenza A H1N1v Vaccination in Pregnant Women

    Condition:   H1N1v Influenza
    Interventions:   Biological: Focetria;   Biological: Focetria;   Biological: Focetria;   Biological: Focetria
    Sponsors:   Copenhagen Studies on Asthma in Childhood;   Novartis
    Recruiting - verified November 2009
  • Clinical Evaluation of a Silicone Hydrogel Lens

    Condition:   Lotrafilcon A Contact Lens Use
    Intervention:  
    Sponsor:   Novartis
    Recruiting - verified November 2009
  • An Open Label Safety and Tolerability Study of AIN457 in Patients With Moderate to Severe Crohn's Disease

    Conditions:   Crohn's Disease;   Inflammatory Bowel Disease
    Intervention:   Drug: AIN457
    Sponsor:   Novartis Pharmaceuticals
    Enrolling by invitation - verified November 2009
  • Zoledronic Acid for the Prevention of Bone Loss Post-bone Marrow Transplantation for Thalassemia Major Patients

    Conditions:   Beta-Thalassemia;   Bone Marrow Transplantation
    Interventions:   Drug: Zoledronic acid;   Drug: Placebo
    Sponsors:   Tehran University of Medical Sciences;   Novartis;   Hematology-Oncology and Stem Cell Transplantation Research Center
    Recruiting - verified November 2009
  • Study of Everolimus With Paclitaxel and Carboplatin in Patients With Metastatic Melanoma

    Condition:   Metastatic Melanoma
    Interventions:   Drug: Paclitaxel;   Drug: Carboplatin;   Drug: Everolimus
    Sponsors:   Sarah Cannon Research Institute;   Novartis
    Not yet recruiting - verified November 2009
  • Daily Everolimus in Combination With Trastuzumab and Vinorelbine in HER2/Neu Positive Women With Locally Advanced or Metastatic Breast Cancer

    Conditions:   HER2/Neu Over-expressing Locally Advanced Breast Cancer;   Metastatic Breast Cancer
    Interventions:   Drug: everolimus, vinorelbine, trastuzumab;   Drug: vinorelbine + trastuzumab
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified November 2009
  • In-vivo Wettability Grading and Assessment Study

    Condition:   Myopia
    Interventions:   Device: lotrafilcon B;   Device: Balafilcon A;   Device: Senofilcon A;   Device: enfilcon A
    Sponsor:   Novartis
    Recruiting - verified November 2009
  • Effect of Omalizumab in Patients With Severe Persistent Non-atopic Uncontrolled Asthma

    Condition:   Asthma
    Interventions:   Drug: Omalizumab;   Drug: Placebo
    Sponsor:   Novartis
    Recruiting - verified November 2009
  • A Study to Assess the Safety, Tolerability and Efficacy of NVA237 Versus Placebo

    Condition:   Chronic Obstructive Pulmonary Disease
    Interventions:   Drug: Glycopyrronium bromide;   Drug: Placebo
    Sponsor:   Novartis
    Recruiting - verified November 2009
  • Pharmacokinetics and Safety of Panobinostat in Patients With Advanced Solid Tumors and Various Degrees of Hepatic Function

    Condition:   Advanced Solid Tumors
    Intervention:   Drug: panobinostat (LBH589)
    Sponsor:   Novartis Pharmaceuticals
    Not yet recruiting - verified November 2009
  • A Dose Escalation Study in Adult Patients With Advanced Solid Malignancies

    Condition:   Solid Tumors
    Intervention:   Drug: BGJ398
    Sponsor:   Novartis Pharmaceuticals
    Not yet recruiting - verified October 2009
  • Prevention of Micro-architectural Bone Decay in Males With Non-metastatic Prostate Cancer Receiving Androgen Deprivation Therapy (ADT)

    Condition:   Prostate Cancer
    Interventions:   Drug: Zoledronic acid;   Drug: Placebo
    Sponsor:   Austin Health
    Not yet recruiting - verified November 2009
  • Clinical Comparison of Two Silicone Hydrogel Toric Lenses in the US

    Condition:   Astigmatism
    Interventions:   Device: Air Optix (lotrafilcon B);   Device: Biofinity Toric lenses (comfilcon A)
    Sponsor:   Novartis
    Active, not recruiting - verified November 2009
  • Subjective Evaluation of Air Optix Aqua Amongst a Subset of the Contact Lens Wearing Population

    Condition:   Myopia
    Interventions:   Device: Air Optix Aqua (lotrafilcon B);   Device: habitual contact lenses
    Sponsor:   Novartis
    Recruiting - verified November 2009
  • Comparison of the Effects of Indacaterol and Tiotropium on Inspiratory Capacity

    Condition:   Chronic Obstructive Pulmonary Disease
    Interventions:   Drug: Indacaterol;   Drug: Tiotropium
    Sponsor:   Novartis Pharmaceuticals
    Recruiting - verified October 2009
  • A Study to Evaluate the Safety and Immunogenicity of 4 Doses of MenACWY Conjugate Vaccine, Administered Concomitantly With Routine Vaccines, Among Infants Aged 2 Months

    Condition:   Meningococcal Disease
    Intervention:   Biological: MenACWY conjugate vaccine plus routine infant vaccines
    Sponsors:   Novartis;   Novartis Vaccines
    Not yet recruiting - verified October 2009
  • Study of Panobinostat in Combination With Sorafenib in Kidney or Lung Cancers

    Conditions:   Renal Cancer;   Non Small Cell Lung Cancer (NSCLC)
    Intervention:   Drug: Panobinostat (LBH589), Sorafenib
    Sponsors:   Medical University of South Carolina;   Novartis Pharmaceuticals
    Recruiting - verified November 2009
  • Single-blind, Dose-ranging Study of Novel Swine Influenza Virus Vaccine in Japanese Pediatric Subjects

    Condition:   Swine-Origin Influenza A H1N1 Virus
    Intervention:   Biological: Adjuvanted cell-derived, inactivated novel swine origin A/H1N1 monovalent subunit influenza virus vaccine
    Sponsors:   Novartis;   Novartis Vaccines
    Active, not recruiting - verified October 2009
  • Zometa Adjuvant Treatment of Malignant Pleural Effusion Due To Non-Small Cell Lung Cancer

    Conditions:   Malignant Pleural Effusion;   Non Small Cell Lung Cancer
    Intervention:   Drug: zoledronic acid
    Sponsors:   Rochester General Hospital;   Novartis Pharmaceuticals
    Not yet recruiting - verified November 2009
  • Trial of LBH589 in Metastatic Thyroid Cancer

    Condition:   Thyroid Carcinoma
    Intervention:   Drug: LBH589
    Sponsors:   University of Wisconsin, Madison;   Novartis Pharmaceuticals
    Not yet recruiting - verified November 2009
  • A Study of RAD001 in Combination With Cetuximab and Cisplatin in Recurrent and Metastatic Squamous Cell Cancer of the Head and Neck

    Condition:   Head and Neck Cancer
    Interventions:   Drug: RAD001;   Drug: Cetuximab;   Drug: Cisplatin/Carboplatin
    Sponsors:   Sidney Kimmel Comprehensive Cancer Center;   Novartis Pharmaceuticals
    Recruiting - verified November 2009
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