- Conditions: Substance-Related Disorders; Drug Addiction; Substance Abuse
Interventions: Behavioral: Home-Based Intervention; Behavioral: Educational Group
Sponsors: Treatment Research Institute; Treatment Research Institute; University of Minnesota - Clinical and Translational Science Institute
Recruiting - verified April 2012 - Condition: Heroin Addiction
Interventions: Drug: JITAI Combined with psychological intervention; Drug: Methadone; Drug: Traditional Chinese Medicine JITAI
Sponsors: Shanghai Mental Health Center; Shanghai Mental Health Center; Shanghai Center of Biomedicine Development
Recruiting - verified April 2012 - Condition: Cocaine Dependence
Interventions: Drug: Oxytocin; Drug: Saline
Sponsors: Medical University of South Carolina; Medical University of South Carolina
Not yet recruiting - verified April 2012 - Conditions: Nicotine Withdrawal; Tobacco Abstinence
Intervention: Device: tDCS, prefrontal cortex and parietal cortex
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Psychomotor Impairment
Interventions: Drug: delta-9-tetrahydrocannabinol; Drug: Placebo
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Canadian Institutes of Health Research (CIHR); Health Canada
Not yet recruiting - verified May 2012 - Conditions: Chronic Pain; Opioid Addiction
Interventions: Other: Yoga; Behavioral: Educational Counseling
Sponsors: Yale University; Yale University
Recruiting - verified April 2012 - Condition: Alcohol Dependance
Intervention: Other: rTMS (repetitive transcranial magnetic stimulation)
Sponsors: Institut National de la Santé Et de la Recherche Médicale, France; Institut National de la Santé Et de la Recherche Médicale, France
Recruiting - verified March 2012 - Conditions: Fabry Disease; Neuropathic Pain
Interventions: Drug: Gabapentin; Drug: placebo
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute; Genzyme
Recruiting - verified April 2012 - Condition: Alcoholism
Interventions: Drug: Ondansetron + Brief Behavioral Enhancement Treatment; Drug: Placebo + Brief Behavioral Enhancement Treatment
Sponsors: University of Virginia; Bankole Johnson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - verified May 2012 - Condition: Prescription Opiate/Medication Dependence
Intervention: Drug: Vivitrol
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified April 2012 - Condition: Nicotine Dependence
Intervention: Drug: Intravenous Nicotine
Sponsors: Mclean Hospital; Mclean Hospital; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Conditions: Alcohol-Related Disorders; Substance-Related Disorders; Substance Abuse
Interventions: Other: ASSIST-linked brief intervention for hazardous and harmful substance use.; Other: Observation
Sponsors: Pontificia Universidad Catolica de Chile; Pontificia Universidad Catolica de Chile; Servicio Nacional para la Prevención y Rehabilitación del Consumo de Drogas y Alcohol (SENDA)
Recruiting - verified April 2012 - Condition: Drug Abuse/Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Methamphetamine Dependence
Intervention: Behavioral: Text messages
Sponsors: New Leaf Treatment Center; New Leaf Treatment Center
Recruiting - verified April 2012 - Condition: Induced Pluripotent Stem Cells
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Alcohol Abuse; Schizophrenia; Bipolar Disorder; Major Depressive Disorder
Intervention: Behavioral: Contingency Management
Sponsors: University of Washington; University of Washington
Not yet recruiting - verified March 2012 - Condition: Usage of Prescription Opioids
Intervention:
Sponsors: Analgesic Solutions; Analgesic Solutions
Not yet recruiting - verified March 2012 - Condition: Substance-Related Disorders
Intervention: Drug: naltrexone for extended release injectable suspension
Sponsors: Rhode Island Hospital; Rhode Island Hospital; National Institute on Drug Abuse (NIDA); Alkermes
Recruiting - verified March 2012 - Condition: Low Back Pain
Interventions: Drug: Methadone; Drug: Buprenorphine/naloxone
Sponsors: State University of New York at Buffalo; State University of New York at Buffalo
Recruiting - verified March 2012 - Condition: Methamphetamine Dependence
Interventions: Drug: Atomoxetine; Drug: placebo
Sponsors: University of Arkansas; University of Arkansas; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Crack Abuse or Dependence
Interventions: Behavioral: Case Management (Strength-Based); Behavioral: Usual Treatment
Sponsors: Federal University of Rio Grande do Sul; Federal University of Rio Grande do Sul; Hospital de Clinicas de Porto Alegre; Brazilian Secretariat for Drug Policies (SENAD); Federal University of Bahia; Universidade Federal do Espirito Santo; Federal University of Rio de Janeiro; Faculdade de Medicina do ABC; Universidade de Brasília
Recruiting - verified March 2012 - Condition: Maternal Opioid Dependency During Pregnancy
Intervention: Drug: Buprenorphine
Sponsors: Johns Hopkins University; Johns Hopkins University
Recruiting - verified March 2012 - Condition: Nicotine Addiction
Intervention: Drug: Galantamine ER
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified March 2012 - Conditions: Traumatic Brain Injury; Substance Abuse; Substance Dependence
Interventions: Drug: Citicoline; Drug: Omega-3; Other: Rice bran oil; Other: Microcrystalline Cellulose
Sponsors: University of Utah; Deborah Yurgelun-Todd
Not yet recruiting - verified January 2012 - Conditions: Cocaine Dependence; Opioid Dependence; Alcoholism; Pathological Gamblers; Adolescents
Intervention:
Sponsors: Yale University; Yale University; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Conditions: Treatment Noncompliance; Bipolar Disorder
Interventions: Behavioral: Customized Adherence Enhancement (CAE); Behavioral: broadly-directed, non-individualized education (EDU)
Sponsors: University Hospitals of Cleveland; University Hospitals of Cleveland; National Institute of Mental Health (NIMH); Case Western Reserve University
Not yet recruiting - verified March 2012 - Conditions: Schizophrenia; Schizoaffective Disorder
Interventions: Drug: DAR-100A; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute
Recruiting - verified January 2012 - Conditions: Adolescent Substance Abuse; Attention Deficit Hyperactivity Disorder
Intervention: Behavioral: Medication integration protocol
Sponsors: The National Center on Addiction and Substance Abuse at Columbia University; The National Center on Addiction and Substance Abuse at Columbia University
Recruiting - verified February 2012 - Conditions: Opioid Withdrawal; Physical Dependence
Intervention: Drug: Ondansetron
Sponsors: Stanford University; Stanford University; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Conditions: No Condition; Brain GABA-B Function
Interventions: Drug: Baclofen 10mg; Drug: Baclofen 60mg; Drug: placebo
Sponsors: Imperial College London; Imperial College London; Medical Research Council
Not yet recruiting - verified March 2012 - Conditions: Breast Cancer; Cancer Survivor; Colorectal Cancer; Lung Cancer; Prostate Cancer; Tobacco Use Disorder
Interventions: Drug: memantine hydrochloride; Other: placebo
Sponsors: National Cancer Institute (NCI); Comprehensive Cancer Center of Wake Forest University; National Cancer Institute (NCI)
Not yet recruiting - verified February 2012 - Condition: Methamphetamine Metabolism, CYP2D6 Genotype
Intervention: Drug: A single oral 5 mg of duterium labeled methamphetamine
Sponsors: California Pacific Medical Center Research Institute; California Pacific Medical Center Research Institute; The Children's Mercy Hospital
Not yet recruiting - verified October 2009 - Conditions: Pancreatitis, Chronic; Abdominal Pain; Chronic Pain
Interventions: Drug: Tetrahydrocannabinol; Drug: Placebo
Sponsors: Radboud University; Radboud University; European Union
Not yet recruiting - verified February 2012 - Conditions: Smoking Cessation; Smoking; Habits
Interventions: Drug: varenicline; Drug: Nicotine cutaneous patch
Sponsors: University of Oulu; Tuula Toljamo; Helsinki University; Helsinki University Central Hospital; University of Oulu
Not yet recruiting - verified February 2012 - Conditions: Opioid-related Disorders; Opiate Dependence; Opiate Addiction; Opiate Abuse
Intervention: Genetic: COMT polymorphism
Sponsors: Assistance Publique - Hôpitaux de Paris; Assistance Publique - Hôpitaux de Paris
Not yet recruiting - verified April 2012 - Condition: Substance Dependence
Intervention: Other: No intervention
Sponsors: Federal University of São Paulo; Federal University of São Paulo; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.; Associação Fundo de Incentivo à Pesquisa
Not yet recruiting - verified March 2012 - Conditions: Depressive Disorder; Major Depressive Disorder; Dysthymic Disorder; Alcohol-Related Disorders; Alcoholism
Intervention: Behavioral: Cognitive Behavioral Analysis System of Psychotherapy
Sponsors: University of Virginia; University of Virginia
Recruiting - verified February 2012 - Condition: Opioid Dependence
Interventions: Drug: Aprepitant; Drug: Placebo pill
Sponsors: New York University; New York University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Nicotine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Cannabis-use Disorders
Intervention: Drug: Tiagabine
Sponsors: University of Kentucky; University of Kentucky
Recruiting - verified January 2012 - Condition: Nicotine Dependence
Intervention: Drug: Varenicline or placebo
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)
Recruiting - verified February 2012 - Condition: Nicotine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Conditions: Alcoholism,; Alcoholic Liver Disease
Interventions: Drug: Metadoxine; Drug: Placebo
Sponsors: Brown University; Brown University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting - verified January 2012 - Conditions: Chronic Pain; Opioid Abuse, Unspecified Use
Interventions: Behavioral: Mindfulness-Oriented Recovery Enhancement; Behavioral: Conventional Support Group (SG)
Sponsors: Florida State University; Florida State University; National Institute on Drug Abuse (NIDA); Fahs Beck Fund for Research and Experimentation
Recruiting - verified March 2012 - Condition: Chronic Pain
Intervention: Behavioral: Therapeutic Education System (TES) for chronic pain
Sponsors: National Development and Research Institutes, Inc.; National Development and Research Institutes, Inc.; National Institute on Drug Abuse (NIDA); Beth Israel Medical Center
Not yet recruiting - verified December 2011 - Condition: Addiction
Interventions: Drug: Atomoxetine; Drug: Sugar Pill
Sponsors: Yale University; Yale University
Recruiting - verified December 2011 - Condition: Cocaine Use Disorders
Interventions: Drug: High-dose donepezil; Drug: Low-dose donepezil; Drug: Selegiline; Drug: Placebo
Sponsors: Midwest Biomedical Research Foundation; Midwest Biomedical Research Foundation; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Condition: Addiction
Interventions: Drug: Galantamine; Drug: Placebo
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Nicotine Addiction
Interventions: Drug: Saline; Drug: Nicotine
Sponsors: Yale University; Yale University
Recruiting - verified December 2011 - Conditions: Alcohol Abuse; Alcohol Dependence; Drug Abuse; Drug Dependence
Intervention: Behavioral: Integrated Twelve-Step Facilitation
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified April 2012 - Conditions: Adolescents; Conduct Disorder; Vulnerability to Substance Addicition
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified May 2012 - Condition: Schizophrenia
Interventions: Drug: Nicotine polacrilex; Drug: Regular chewing gum; Dentyne Ice, Wrigely´s Mint Gum
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health
Recruiting - verified January 2012 - Condition: Healthy
Interventions: Drug: Placebo; Drug: Vorikonazole
Sponsors: Turku University Hospital; Turku University Hospital
Recruiting - verified November 2011 - Condition: Substance-Related Disorders
Interventions: Behavioral: Substance Abuse Education; Behavioral: Mind-body Bridging
Sponsors: University of Utah; University of Utah
Recruiting - verified April 2012 - Condition: Treatment-Resistant Depression Disease
Interventions: Other: Repetitive Transcranial Magnetic Stimulation; Other: Sham rTMS
Sponsors: Tehran University of Medical Sciences; Tehran University of Medical Sciences
Not yet recruiting - verified November 2011 - Condition: Smoking Cessation
Interventions: Drug: Placebo; Drug: varenicline tartrate; Drug: bupropion hydrochloride; Drug: Nicotine Replacement Therapy Patch
Sponsors: Pfizer; Pfizer; GlaxoSmithKline
Recruiting - verified May 2012 - Conditions: Stress Disorders, Post-Traumatic; Substance-Related Disorders
Interventions: Behavioral: Cognitive Behavioral Therapy for PTSD; Behavioral: Individual Addiction Counseling; Behavioral: Treatment as usual
Sponsors: Dartmouth-Hitchcock Medical Center; Dartmouth-Hitchcock Medical Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Condition: Smoking
Intervention: Behavioral: Behavior smoking cessation counseling with nicotine patch
Sponsors: Brown University; Brown University; National Cancer Institute (NCI)
Recruiting - verified October 2011 - Conditions: Stress Disorder, Post-Traumatic; Substance-Related Disorders
Interventions: Behavioral: Integrated Cognitive Behavioral Therapy; Behavioral: Treatment-as-usual
Sponsors: Dartmouth-Hitchcock Medical Center; Dartmouth-Hitchcock Medical Center; Brown University; Providence VA Medical Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Healthy Volunteer
Interventions: Drug: RO4917838; Drug: diazepam; Drug: Placebo
Sponsors: Hoffmann-La Roche; Hoffmann-La Roche
Recruiting - verified April 2012 - Conditions: Smoking; Addiction
Intervention: Drug: Nicabate 21mg Transdermal Nicotine Replacement Therapy (NRT)Patch
Sponsors: The Queen Elizabeth Hospital; The Queen Elizabeth Hospital; Basil Hetzel Institute for Translational Research; University of Adelaide; University of South Australia; Clinical Practice Unit; Therapeutics Research Centre
Recruiting - verified September 2011 - Conditions: Substance Abuse; Substance Dependence; Cognitive Impairment
Interventions: Behavioral: Cognitive Training + Work Therapy; Behavioral: Work Therapy
Sponsors: Yale University; Yale University
Recruiting - verified August 2011 - Conditions: Alcohol Dependence; Anxiety
Interventions: Drug: Doxazosin; Drug: Placebo
Sponsors: Brown University; Brown University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified September 2011 - Conditions: Addictions; Adolescents; Primary Health Care; Brief Intervention
Intervention: Behavioral: Brief Intervention
Sponsors: University Hospital, Clermont-Ferrand; University Hospital, Clermont-Ferrand
Not yet recruiting - verified September 2011 - Condition: Addiction
Intervention: Behavioral: STICA Intervention
Sponsors: Johannes Gutenberg University Mainz; Johannes Gutenberg University Mainz
Recruiting - verified March 2012 - Condition: Schizophrenia
Interventions: Drug: Lurasidone; Drug: Matching Placebo
Sponsors: Sunovion; Sunovion
Recruiting - verified April 2012 - Conditions: Obesity; Phentermine Withdrawal
Intervention: Drug: Abrupt cessation of phentermine pharmacotherapy
Sponsors: Center for Weight Management, California; Center for Weight Management, California; American Society of Bariatric Physicians
Recruiting - verified August 2011 - Condition: Smoking
Interventions: Drug: Nicotine replacement therapy; Other: No intervention
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Canadian Institutes of Health Research (CIHR)
Not yet recruiting - verified April 2012 - Conditions: Infection; Hypertension; Anesthesia; Pain; Reflux
Intervention:
Sponsors: Duke University; Duke University; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); The EMMES Corporation
Recruiting - verified April 2012 - Condition: Opioid Dependence
Intervention:
Sponsors: Alkermes; Alkermes
Recruiting - verified April 2012 - Conditions: Dosimetry; Pharmacokinetics
Intervention: Drug: [11C]LY2428703
Sponsors: National Institutes of Health Clinical Center (CC); National Institute of Mental Health (NIMH)
Recruiting - verified January 2012 - Conditions: HIV; Drug Addiction
Interventions: Behavioral: Psycho-education; Behavioral: Experimental
Sponsors: RTI International; RTI International; University of Cape Town
Recruiting - verified December 2011 - Conditions: Nicotine Dependence; Opiate Dependence
Interventions: Behavioral: Intensive, tailored intervention; Behavioral: NJ Quitline Referral
Sponsors: University of Medicine and Dentistry New Jersey; University of Medicine and Dentistry New Jersey; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Conditions: Human Immunodeficiency Virus; Acquired Immunodeficiency Syndrome; Opiate Addiction; Drug Dependence
Intervention: Drug: Buprenorphine/naloxone
Sponsors: Yale University; Yale University; George Mason University; Howard University
Recruiting - verified April 2012 - Conditions: Alcoholism; Substance-Related Disorders; Smoking; Chronic Disease; Malnutrition
Intervention: Behavioral: Health promotion activities
Sponsors: Skane University Hospital; Skane University Hospital; Swedish Council for Working Life and Social Research; The Swedish Council for Information on Alcohol and Other Drugs; Lund University; Copenhagen University Hospital, Denmark
Recruiting - verified October 2011 - Condition: Cocaine Dependence
Interventions: Drug: Buprenorphine + Naltrexone; Drug: Placebo + Naltrexone
Sponsors: University of California, Los Angeles; Walter Ling; National Institute on Drug Abuse (NIDA); The EMMES Corporation
Recruiting - verified February 2012 - Conditions: Impulsive Behavior; Substance Abuse; HIV Risk Behavior; Anxiety; Depression; Criminogenic Thinking
Interventions: Behavioral: REVAMP; Behavioral: TAU
Sponsors: George Mason University; George Mason University
Recruiting - verified June 2011 - Condition: Cocaine Dependence
Interventions: Drug: Oral tacrine; Drug: Oral placebo
Sponsors: Midwest Biomedical Research Foundation; Midwest Biomedical Research Foundation
Not yet recruiting - verified May 2012 - Conditions: Alcoholism; Genetics
Intervention: Drug: Ethanol
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified April 2012 - Conditions: Domestic Violence; Substance Abuse; Parenting
Interventions: Behavioral: Fathers for Change; Behavioral: Individual Drug Counseling
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Stress Disorders, Post-Traumatic; Substance-Related Disorders
Interventions: Behavioral: Concurrent Treatment of PTSD and Substance Dependence; Behavioral: Relapse Prevention Treatment
Sponsors: The City College of New York; The City College of New York; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Substance Related Disorders; Drug Addiction; Substance Abuse
Interventions: Behavioral: Cash CM; Behavioral: Voucher CM; Behavioral: Non-CM Control
Sponsors: Treatment Research Institute; Treatment Research Institute; National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Condition: Smoking Cessation
Interventions: Drug: D-cycloserine; Drug: Placebo
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified July 2011 - Condition: Alcoholism
Interventions: Behavioral: SMART Recovery face-to-face meetings; Behavioral: Overcoming Addictions web application
Sponsors: Behavior Therapy Associates, LLP; Behavior Therapy Associates, LLP; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified September 2011 - Conditions: Cocaine Abuse or Dependence; Cocaine Related Disorders
Intervention:
Sponsors: Wayne State University; Wayne State University
Recruiting - verified October 2011 - Conditions: HIV Risk Behaviors; Heroin Injection; Retention in Methadone Treatment
Interventions: Behavioral: Behavioral Drug and Risk Counseling (BDRC); Behavioral: methadone maintenance treatment
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2011 - Condition: Metastatic Breast Cancer
Intervention: Other: Biopsy
Sponsors: UNICANCER; UNICANCER; Ministry of Health, France; Institut Gustave Roussy
Recruiting - verified August 2011 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: Bupropion; Drug: Nicotine patches
Sponsors: Duke University; Duke University; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Conditions: Substance-Related Disorders; Drug Addiction; Substance Abuse
Interventions: Behavioral: Community Reinforcement and Family Training; Behavioral: Al-Anon Facilitation
Sponsors: Treatment Research Institute; Treatment Research Institute; Robert J. Meyers PhD & Associates
Recruiting - verified December 2011 - Conditions: Attention Deficit Hyperactivity Disorder; Attention Deficit Disorder
Intervention: Behavioral: MIP Protocol
Sponsors: The National Center on Addiction and Substance Abuse at Columbia University; The National Center on Addiction and Substance Abuse at Columbia University; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified February 2012 - Condition: Pain
Interventions: Behavioral: Psychoeducation for substance abuse; Behavioral: CBT for pain in Substance abuse
Sponsors: University of Michigan; University of Michigan; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified June 2011 - Conditions: Cigarette Smoking; Drug Use
Interventions: Behavioral: Standard Treatment; Behavioral: BAD-AS; Drug: Transdermal Nicotine Patch
Sponsors: University of Maryland; University of Maryland; American Cancer Society
Recruiting - verified July 2011 - Conditions: Chronic Pain; Opioid Dependence
Interventions: Drug: Varenicline; Drug: Placebo
Sponsors: Mayo Clinic; Mayo Clinic
Recruiting - verified May 2012 - Conditions: Major Depressive Disorder, Recurrent, Unspecified; Major Depressive Disorder, Single Episode, Unspecified
Intervention: Other: H-Coil Deep TMS in combination with SSRIs
Sponsors: Brainsway; Brainsway
Not yet recruiting - verified May 2011 - Condition: Opiate Dependence
Interventions: Behavioral: Behavioral Drug and HIV Risk Reduction Counseling; Behavioral: Educational Counseling; Behavioral: Treatment as Usual
Sponsors: Yale University; Yale University; Centers for Disease Control and Prevention, China
Recruiting - verified July 2011 - Condition: Methamphetamine Dependence
Intervention: Drug: Modafinil
Sponsors: California Pacific Medical Center Research Institute; California Pacific Medical Center Research Institute
Recruiting - verified January 2012 - Condition: Healthy Smokers
Intervention: Behavioral: Mindfulness behavioral intervention (MT),cognitive behavioral intervention (CBT)
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital
Recruiting - verified May 2011 - Conditions: Alcohol Consumption; Unsafe Sex
Interventions: Behavioral: Brief Motivational Intervention (BMI); Behavioral: Brief Advice
Sponsors: Brown University; Brown University; National Institute on Alcohol Abuse and Alcoholism (NIAAA); Memorial Hospital of Rhode Island; Kent Hospital
Recruiting - verified November 2011 - Conditions: Cocaine Addiction; Cocaine-related Disorder; Executive Dysfunction
Intervention: Device: transcranial Direct Current Stimulation
Sponsors: Federal University of Espirito Santo; Federal University of Espirito Santo; Harvard University; University of Göttingen
Recruiting - verified March 2011 - Conditions: Substance Abuse; Substance Dependence; Alcohol Abuse; Drug Use; Relapse
Interventions: Behavioral: Dual Processing; Behavioral: Relapse Prevention
Sponsors: Inova Health Care Services; Inova Health Care Services; Virginia Commonwealth University; Georgetown University
Recruiting - verified August 2011 - Condition: Drug Addiction
Intervention: Drug: Varenicline
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified December 2011 - Conditions: Chronic Pain; Opiate Dependence
Interventions: Behavioral: Cognitive-Behavioral Therapy for Pain and Opioid Dependence; Behavioral: Methadone Drug Counseling
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Conditions: HIV; Medication Adherence; Substance Dependence
Intervention: Behavioral: Spiritual Self-Schema Therapy
Sponsors: Hunter College; Hunter College; Fordham University
Recruiting - verified February 2011 - Conditions: Alcoholism; Cocaine Dependence
Interventions: Drug: Vigabatrin; Drug: Placebo
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified August 2011 - Conditions: Alcohol Dependence; Executive Dysfunction; Abnormal Craving for Drugs
Intervention: Device: transcranial Direct Current Stimulation
Sponsors: Federal University of Espirito Santo; Federal University of Espirito Santo; Harvard University; University of Göttingen
Recruiting - verified October 2010 - Condition: Smoking
Interventions: Other: Brief computerized feedback; Other: Resources only (control)
Sponsors: Virginia Commonwealth University; Virginia Commonwealth University
Recruiting - verified October 2011 - Condition: Nicotine Addiction
Interventions: Drug: Varenicline; Drug: Placebo; Drug: Transdermal Nicotine
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Recruiting - verified January 2012 - Conditions: Psychosis; Substance Abuse
Interventions: Behavioral: Skills trainig for patients with dual diagnosis; Behavioral: regular treatment
Sponsors: University of Cologne; University of Cologne
Recruiting - verified February 2011 - Condition: Nicotine Dependence
Interventions: Drug: Varenicline; Drug: Bupropion; Drug: Nicotine patches; Drug: Nicotine Inhaler
Sponsors: Duke University; Duke University; National Institute on Drug Abuse (NIDA); Philip Morris USA, Inc.
Recruiting - verified March 2012 - Condition: Human Immunodeficiency Virus
Interventions: Behavioral: RBT; Other: Case-Management
Sponsors: RTI International; RTI International; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Condition: Tobacco Use Disorder
Intervention:
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Pfizer
Recruiting - verified March 2012 - Conditions: Alcohol Dependence; Alcohol Abuse
Interventions: Drug: Naltrexone; Behavioral: Brenda Therapy Sessions
Sponsors: University of North Carolina, Chapel Hill; University of North Carolina, Chapel Hill; National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes of Health (NIH)
Recruiting - verified January 2012 - Conditions: Smoking Cessation; Alcohol Abuse
Interventions: Drug: varenicline; Drug: placebo
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Ontario Lung Association
Recruiting - verified April 2012 - Condition: Cocaine Dependence
Intervention: Drug: Buspirone
Sponsors: The University of Texas Health Science Center, Houston; The University of Texas Health Science Center, Houston
Recruiting - verified March 2012 - Condition: Bipolar
Interventions: Drug: Lurasidone; Drug: Placebo
Sponsors: Sunovion; Sunovion
Recruiting - verified April 2012 - Conditions: Cocaine Dependence; Crack Cocaine Dependence
Interventions: Drug: Biperiden; Drug: Placebo
Sponsors: Federal University of São Paulo; Federal University of São Paulo; Nacional Conseling of Scientific Development and Technology, Brazil; Association for Psychopharmacological Research, Brazil
Recruiting - verified March 2012 - Conditions: HIV; AIDS; Opioid Dependence; Drug Dependence
Intervention: Drug: Depot Naltrexone
Sponsors: Yale University; Yale University; Baystate Medical Center
Recruiting - verified August 2011 - Condition: Substance Use Disorders
Intervention: Behavioral: Computerized cognitively stimulating activities
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Tobacco Use Disorder; Smoking Relapse; Cognitive Training; Nicotine Addiction
Interventions: Behavioral: Cognitive Remediation Training (CRT); Behavioral: Standard Care (SC)
Sponsors: University of Pennsylvania; University of Pennsylvania
Recruiting - verified January 2012 - Conditions: PTSD; Substance Addiction
Interventions: Behavioral: Prolonged Exposure; Behavioral: Motivational Enhancement Therapy
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Condition: Nicotine Dependence
Interventions: Drug: Baclofen 30 mg/day; Drug: placebo pill; Drug: Baclofen 60 mg/day
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Canadian Tobacco Control Research Initiative
Recruiting - verified December 2011 - Conditions: Alcohol-Related Disorders; Alcohol Dependence; Alcoholism; Anxiety Disorder
Interventions: Drug: Pexacerfont; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified August 2011 - Condition: Cocaine Use
Intervention: Device: Repetitive Transcranial Magnetic Stimulation
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA); University of Maryland
Not yet recruiting - verified August 2011 - Condition: Healthy Young and Elderly Volunteers
Interventions: Drug: Intravenous Citalopram; Drug: Normal Saline
Sponsors: Rotman Research Institute at Baycrest; Rotman Research Institute at Baycrest; Centre for Addiction and Mental Health; University of Toronto
Recruiting - verified January 2012 - Condition: Drug Abuse
Interventions: Behavioral: screening; Behavioral: assessment; Behavioral: referral; Behavioral: Brief intervention; Behavioral: booster sessions
Sponsors: University of New Mexico; University of New Mexico; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Smoking Addiction
Interventions: Drug: Placebo; Drug: Varenicline
Sponsors: The Mind Research Network; The Mind Research Network; National Institute on Drug Abuse (NIDA)
Recruiting - verified November 2011 - Condition: Traumatic Brain Injury
Intervention: Other: Blood/saliva sampling
Sponsors: The University of Texas Health Science Center, Houston; The University of Texas Health Science Center, Houston
Recruiting - verified February 2012 - Conditions: Substance Use Disorders; Posttraumatic Stress Disorder
Interventions: Behavioral: Prolonged Exposure Therapy; Behavioral: Prolonged Exposure therapy + VR/ER
Sponsors: Duke University; Duke University; Department of Defense; Telemedicine and Advanced Technology Research Center
Recruiting - verified January 2012 - Condition: Alcohol Dependence
Interventions: Drug: GSK561679; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified November 2011 - Condition: Alcoholism
Interventions: Drug: Ghrelin; Drug: Ghrelin; Drug: Saline solution
Sponsors: Brown University; Brown University
Recruiting - verified August 2010 - Conditions: Substance Abuse; Substance Dependence
Intervention: Behavioral: Behavioral Intervention
Sponsors: Feinstein Institute for Medical Research; Feinstein Institute for Medical Research; National Institute of Mental Health (NIMH)
Not yet recruiting - verified June 2010 - Conditions: Opioid Related Disorders; Opioid Dependence; Opioid Addiction
Interventions: Drug: Buprenorphine/naloxone; Drug: Clonidine; Drug: Tramadol ER
Sponsors: National Institute on Drug Abuse (NIDA); National Institute on Drug Abuse (NIDA)
Recruiting - verified April 2012 - Conditions: Alcohol Dependence; Nicotine Dependence
Interventions: Drug: Topiramate with brief behavioral enhancement therapy; Drug: Placebo plus brief behavioral enhancement therapy
Sponsors: University of Virginia; University of Virginia; National Institute on Alcohol Abuse and Alcoholism (NIAAA); M.D. Anderson Cancer Center; University of California, San Diego
Recruiting - verified March 2012 - Condition: Smoking Cessation
Intervention: Other: Respiragene test
Sponsors: University of Surrey; University of Surrey; Lab 21, Cambridge; NHS Research and Development
Recruiting - verified March 2012 - Conditions: Drug Addiction; Nicotine Dependence
Intervention: Drug: Nicotrol
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Condition: Anorexia Nervosa
Interventions: Drug: Olanzapine; Drug: Placebo
Sponsors: New York State Psychiatric Institute; New York State Psychiatric Institute; National Institute of Mental Health (NIMH); Weill Medical College of Cornell University; University of Pittsburgh; Johns Hopkins University; University of Toronto
Recruiting - verified April 2012 - Condition: Cocaine Dependence
Interventions: Drug: Zonisamide; Drug: Placebo; Drug: Cocaine Hydrochloride; Behavioral: Neurocognitive and Performance Battery; Behavioral: Smoking Assessments
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Condition: Alcohol Dependence
Interventions: Drug: Quetiapine XR plus mirtazapine; Drug: Quetiapine fumarate extended release (Quetiapine XR)
Sponsors: Dartmouth-Hitchcock Medical Center; Dartmouth-Hitchcock Medical Center
Recruiting - verified February 2012 - Condition: Behavioral Couples Therapy
Intervention: Behavioral: Individual Substance Abuse Treatment
Sponsors: Old Dominion University; Old Dominion University
Recruiting - verified April 2012 - Condition: Regressors
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Substance Abuse Disorder
Interventions: Behavioral: Low intensity care; Behavioral: Voucher reinforcement
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Condition: Substance Abuse Disorder
Intervention: Behavioral: eGet
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Condition: Substance Use Disorders
Interventions: Behavioral: Voucher Reinforcement; Behavioral: Standard Control
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Drug Abuse (NIDA)
Recruiting - verified August 2011 - Conditions: Cannabis Abuse; Cannabis Dependence
Interventions: Drug: Topiramate; Drug: Placebo
Sponsors: Brown University; Brown University; National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Conditions: HIV; Substance Abuse; HIV Infections
Interventions: Drug: Oral Naltrexone (ON); Drug: Implantable Naltrexone (IN)
Sponsors: University of Pennsylvania; University of Pennsylvania; National Institute on Drug Abuse (NIDA)
Not yet recruiting - verified January 2012 - Condition: Drug Dependence
Intervention: Drug: 2-4 of the drugs listed below
Sponsors: University of Arkansas; University of Arkansas; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Schizophrenia; Schizoaffective Disorder
Intervention: Drug: Varenicline
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Pfizer
Recruiting - verified March 2012 - Condition: Tobacco Dependence
Intervention: Drug: nicotine patch
Sponsors: University of Massachusetts, Worcester; University of Massachusetts, Worcester
Recruiting - verified April 2012 - Conditions: Drug Abuse; Drug Dependence
Intervention:
Sponsors: Nantes University Hospital; Nantes University Hospital
Recruiting - verified January 2010 - Conditions: Alcohol Dependence; Problem Drinking; Hazardous Drinking; Human Immunodeficiency Virus; AIDS
Interventions: Drug: Vivitrol- Intramuscular naltrexone (depot-formulation); Drug: Placebo
Sponsors: Yale University; Yale University; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified August 2011 - Conditions: Drug Abuse; Nicotine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Condition: Evaluation
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Conditions: Alcohol Dependence; PTSD
Interventions: Drug: Propranolol; Drug: Placebo
Sponsors: Medical University of South Carolina; Medical University of South Carolina; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified November 2011 - Conditions: Drug Abuse; Cocaine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA); National Institute of Mental Health (NIMH)
Recruiting - verified July 2011 - Condition: Drug Abuse
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Tobacco Addiction
Intervention: Behavioral: Extended Duration Behavioral Smoking Cessation Counseling
Sponsors: Harvard University Faculty of Medicine; Harvard University Faculty of Medicine; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Condition: Nicotine Dependence
Intervention: Device: Transcranial Magnetic Stimulation
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA); University of Maryland
Recruiting - verified December 2011 - Conditions: Cocaine Dependence; Cocaine Addiction; Cocaine Abuse; Substance Abuse
Interventions: Drug: Placebo; Drug: Rivastigmine; Drug: Huperzine A; Drug: Rivastigmine; Drug: Huperzine A
Sponsors: Baylor College of Medicine; Baylor College of Medicine; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Opiate Addiction
Interventions: Drug: Buprenorphine/naloxone; Drug: Naltrexone
Sponsors: State University of New York at Buffalo; State University of New York at Buffalo
Recruiting - verified February 2011 - Condition: Attention Deficit Hyperactivity Disorder
Interventions: Dietary Supplement: Compound Natural Health Product; Dietary Supplement: Placebo
Sponsors: The Canadian College of Naturopathic Medicine; The Canadian College of Naturopathic Medicine; Health Canada; Centre for Addiction and Mental Health; SickKids Foundation
Not yet recruiting - verified October 2011 - Condition: Drug Dependence
Intervention: Drug: Oxytocin Nasal Spray
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Conditions: Substance-Related Disorders; Dual Diagnosis
Intervention:
Sponsors: Sorlandet Hospital HF; Sorlandet Hospital HF
Recruiting - verified July 2011 - Condition: Adolescent Substance Abuse
Intervention:
Sponsors: The National Center on Addiction and Substance Abuse at Columbia University; The National Center on Addiction and Substance Abuse at Columbia University
Recruiting - verified February 2012 - Conditions: Cocaine Abuse or Dependence; Cocaine Related Disorders
Intervention:
Sponsors: Wayne State University; Wayne State University; National Institute on Drug Abuse (NIDA)
Recruiting - verified October 2011 - Condition: Cocaine Dependence
Interventions: Drug: TA-CD Vaccination; Other: Placebo Injection
Sponsors: Baylor College of Medicine; Baylor College of Medicine; National Institute on Drug Abuse (NIDA); US Department of Veterans Affairs Cooperative Studies Program; VA Maryland Health Care System; Columbia University; VA New York Harbor Healthcare System; University of Pennsylvania; Johns Hopkins University; University of Cincinnati; Celtic Pharma Development Services
Recruiting - verified September 2011 - Conditions: Depressive Symptoms; Substance-related Disorders; Posttraumatic Stress Disorders
Interventions: Behavioral: ICBT: Integrated Cognitive Behavioral Therapy; Behavioral: CPT-M: Cognitive Processing Therapy-Modified
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified December 2011 - Conditions: Drug Abuse; Cocaine Dependence
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Bipolar I Disorder
Interventions: Drug: Escitalopram; Drug: Bupropion XL
Sponsors: University of British Columbia; University of British Columbia; Canadian Institutes of Health Research (CIHR); Glaxo Smith Kline Biovail; H. Lundbeck A/S
Recruiting - verified September 2011 - Condition: Alcohol Drinking
Interventions: Drug: D-cycloserine; Drug: Placebo
Sponsors: Central Institute of Mental Health, Mannheim; Central Institute of Mental Health, Mannheim; German Research Foundation
Recruiting - verified November 2011 - Condition: Alcohol Dependence
Interventions: Drug: Pregabalin; Drug: Duloxetine; Behavioral: Standardized behavioral therapy; Behavioral: Standardized behavioral therapy; Drug: Placebo; Behavioral: Standardized behavioral therapy
Sponsors: The Scripps Research Institute; The Scripps Research Institute; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified June 2011 - Condition: Pathological Gambling
Intervention: Drug: Tolcapone
Sponsors: University of Minnesota - Clinical and Translational Science Institute; University of Minnesota - Clinical and Translational Science Institute
Recruiting - verified March 2012 - Condition: Opiate Addiction
Interventions: Other: Brief Intervention with Buprenorphine initiation; Behavioral: Brief Intervention
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Condition: Tardive Dyskinesia
Interventions: Drug: Pyridoxal 5'-Phosphate; Drug: Placebo
Sponsors: Medicure; Medicure
Recruiting - verified September 2011 - Condition: Bone Scan
Intervention: Other: 18F-Sodium Fluoride (Na18F)
Sponsors: Alberta Health Services; Alberta Health Services
Recruiting - verified April 2012 - Conditions: HIV Infections; Drug Abuse
Interventions: Drug: Disulfiram; Drug: Disulfiram + Efavirenz; Drug: Disulfiram + Atazanavir; Drug: Disulfiram + Ritonavir
Sponsors: University of California, San Francisco; University of California, San Francisco; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Alzheimer's Disease; Agitation
Interventions: Drug: citalopram; Drug: placebo
Sponsors: Johns Hopkins University; Johns Hopkins University; National Institute on Aging (NIA); National Institute of Mental Health (NIMH)
Recruiting - verified May 2012 - Conditions: Alcohol Abuse; Alcoholism
Interventions: Drug: Ondansetron + BASICS Plus; Drug: Placebo + BASICS Plus
Sponsors: University of Virginia; Bankole Johnson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012 - Conditions: Alcohol Dependence; Depression
Interventions: Behavioral: Interpersonal Psychotherapy for Co-occurring Alcohol Dependence and Major Depression (IPT-ADMD); Behavioral: Treatment as Usual
Sponsors: University of Rochester; University of Rochester; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012 - Conditions: Domestic Violence; Substance Abuse
Interventions: Behavioral: substance abuse/domestic violence treatment; Behavioral: Cognitive behavioral therapy addressing substance abuse
Sponsors: VU University of Amsterdam; VU University of Amsterdam
Recruiting - verified January 2012 - Conditions: Bipolar; Depression
Intervention: Drug: lurasidone
Sponsors: Sunovion; Sunovion
Recruiting - verified April 2012 - Conditions: Domestic Violence; Substance Abuse
Interventions: Behavioral: substance abuse/domestic violence treatment; Behavioral: CBT addression paertner violence
Sponsors: VU University of Amsterdam; VU University of Amsterdam
Recruiting - verified January 2012 - Condition: Obsessive Compulsive Disorder
Interventions: Drug: clomipramine; Drug: escitalopram; Drug: duloxetine
Sponsors: Sunnybrook Health Sciences Centre; Sunnybrook Health Sciences Centre; Obsessive Compulsive Foundation; Centre for Addiction and Mental Health
Recruiting - verified July 2011 - Cognitive Behavioral Social Skills Training for Patients With Late-Life Schizophrenia: a Pilot StudyCondition: Schizophrenia
Interventions: Behavioral: Cognitive Behavioral Social Skills Training (CBSST) plus treatment as usual; Behavioral: Treatment as usual (TAU)
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health
Recruiting - verified November 2011 - Conditions: Schizophrenia; Schizoaffective Disorder; Schizophreniform Disorder
Intervention: Drug: risperidone
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health
Recruiting - verified April 2012 - Conditions: Cancer of the Upper Aero-digestive Tract; Alcoholism
Intervention: Procedure: Hospitalization for a week
Sponsors: Centre Hospitalier Universitaire de Nice; Department of Clinical Research and Innovation; National Cancer Institute, France
Recruiting - verified December 2011 - Condition: Substance Abuse
Interventions: Drug: Nicotine Replacement Treatment (NRT); Behavioral: Brief Advice
Sponsors: Brown University; Brown University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2009 - Conditions: Psychological Stress; Drug Abuse
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Conditions: Cocaine Dependence; Cocaine-Related Disorders; Opioid-Related Disorders
Interventions: Drug: Airipiprazole; Drug: Placebo
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Drug Abuse (NIDA)
Recruiting - verified July 2011 - Conditions: Smoking Cessation; Nicotine Dependence
Interventions: Drug: Nicotine Replacement Treatment (NRT); Drug: varenicline; Behavioral: Behavioral counseling for smoking cessation; Drug: Placebo patch; Drug: Placebo
Sponsors: Brown University; Brown University; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2009 - Condition: Substance Use Disorders
Interventions: Behavioral: A Woman's Path to Recovery (WPR); Behavioral: Twelve-Step Facilitation (TSF)
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Conditions: Alcohol Dependence; Dual Diagnosis; Drug Dependence
Intervention: Behavioral: In-Home-Messaging-Device (IHMDs)
Sponsors: Department of Veterans Affairs; Department of Veterans Affairs
Recruiting - verified March 2012 - Conditions: Schizophrenia; Schizoaffective Disorder; Schizophreniform Disorder; Delusional Disorder; Psychotic Disorder
Intervention: Drug: Risperidone/Olanzapine and PET scans
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health
Recruiting - verified April 2012 - Conditions: Alcohol Dependence; Anxiety Disorder
Intervention: Drug: disulfiram plus lorazepam
Sponsors: University of New Mexico; University of New Mexico; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified January 2012 - Conditions: Major Depressive Disorder; Dysthymic Disorder; Anxiety Disorders; Generalized Anxiety Disorder; Social Anxiety Disorder; Panic Disorder; Post-traumatic Stress Disorder
Interventions: Drug: Quetiapine; Drug: Placebo
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health
Recruiting - verified April 2012 - Condition: Cocaine Dependence
Interventions: Drug: Ondansetron; Drug: Placebo
Sponsors: University of Virginia; University of Virginia; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Usual Aftercare; Oxford House; Therapeutic Community
Interventions: Other: Residential; Other: Residential
Sponsors: DePaul University; DePaul University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Condition: Cocaine Related Disorders
Intervention:
Sponsors: National Institute on Drug Abuse (NIDA); National Institute on Drug Abuse (NIDA)
Recruiting - verified September 2011 - Condition: Cocaine Addiction
Interventions: Behavioral: I/GDC + VR/CER; Behavioral: I/GDC
Sponsors: Duke University; Duke University; National Institute on Drug Abuse (NIDA)
Recruiting - verified June 2011 - Conditions: Cocaine Dependent; Alcohol Dependent
Interventions: Drug: Guanfacine; Drug: Placebo
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified March 2012 - Condition: Cocaine Addictions
Interventions: Drug: sugar pill; Drug: carvedilol; Drug: Methadone
Sponsors: Yale University; Yale University; National Institute on Drug Abuse (NIDA)
Recruiting - verified December 2011 - Condition: Schizophrenia
Intervention: Dietary Supplement: Sarcosine
Sponsors: Massachusetts General Hospital; Massachusetts General Hospital; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Condition: Depression
Intervention: Drug: escitalopram
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Queen's University
Recruiting - verified January 2012 - Conditions: Alcohol Dependence; Cocaine Dependence
Interventions: Drug: Topiramate + Cognitive Behavioral Therapy; Drug: Placebo + Cognitive Behavioral Therapy
Sponsors: University of Virginia; Bankole Johnson; National Institute on Drug Abuse (NIDA)
Recruiting - verified February 2012 - Conditions: Mycoses; Candidiasis, Invasive; Candidemia
Interventions: Drug: Isavuconazole; Drug: Caspofungin; Drug: Voriconazole
Sponsors: Astellas Pharma Inc; Astellas Pharma Inc; Basilea Pharmaceutica
Recruiting - verified May 2012 - Condition: Tobacco Use Disorder
Interventions: Drug: Bupropion; Drug: Bupropion
Sponsors: Hadassah Medical Organization; Hadassah Medical Organization
Recruiting - verified March 2012 - Condition: Smoking
Interventions: Drug: Nicotine Replacement Therapy; Behavioral: behavioural intervention
Sponsors: Centre for Addiction and Mental Health; Centre for Addiction and Mental Health; Pfizer; Ontario Ministry of Health and Long Term Care
Recruiting - verified February 2012 - Condition: Lung Cancer
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Cancer Institute (NCI)
Recruiting - verified November 2011 - Conditions: Smoking; Tobacco Use Cessation
Interventions: Behavioral: MBAT Group Therapy; Drug: Nicotine; Behavioral: Group Therapy; Behavioral: Individual Therapy
Sponsors: M.D. Anderson Cancer Center; M.D. Anderson Cancer Center; National Institute on Drug Abuse (NIDA)
Recruiting - verified May 2012 - Conditions: Brain Injuries, Traumatic; Traumatic Brain Injury
Intervention: Other: Blood/saliva samples for protein/molecular analysis
Sponsors: The University of Texas Health Science Center, Houston; The University of Texas Health Science Center, Houston; TIRR/Mission Connect; The Center for Clinical and Translational Sciences (CCTS) Clinical Research Unit at The University of Texas Health Science Center at Houston
Recruiting - verified February 2012 - Conditions: Heart Valve Diseases; Parkinson's Disease
Intervention:
Sponsors: German Parkinson Study Group (GPS); German Parkinson Study Group (GPS); Competence Network on Parkinson's Disease
Recruiting - verified April 2011 - Conditions: Alcoholism; Alcohol Dependence; Alcohol Drinking Related Problems
Intervention:
Sponsors: National Institutes of Health Clinical Center (CC); National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified October 2011 - Condition: Alcoholism
Interventions: Drug: ondansetron + cognitive behavioral therapy; Drug: topiramate + cognitive behavioral therapy; Drug: Placebo + cognitive behavioral therapy; Drug: ondansetron + topiramate + cognitive behavioral therapy
Sponsors: University of Virginia; Bankole Johnson; National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting - verified February 2012
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